National Center for Biotechnology InformationFall 1999

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New Entrez Genomes Views:
A Fresh Look at Human Chromosomes

A set of new Entrez Genomes display formats provides an improved vantage point on the human chromosomal sequences in GenBank, facilitating convenient access to finished contig data and more supplementary information than ever before. Figure 1 shows a partial Entrez Genomes view of human chromosome 22, illustrating many of the features highlighted here.

Figure 1

Figure 1

Click on figure to view enlarged version
Entrez Genomes View of Human Chromosome 22.
[Reprinted by permission from Nature 402(6761):489-95, copyright 1999 Macmillan Magazines Ltd.]

For each chromosome, the new Entrez Genomes views now provide:

A graphic depicting sequencing progress with finished regions shown in red: Clicking on a finished region leads to the corresponding contig data.

Sequencing progress statistics: These include euchromatic size, amount of finished sequence given in kilobases or as a percentage of the chromosome, and the number of contigs available for the chromosome.

Links to contig lists sorted by size and position.

Links to various STS maps.

Links to the coordinating chromosome sequencing center: Other sequencing centers that are working on the chromosome are listed as well.

Links to the Mitelman summary of chromosome aberrations associated with cancers.

A selection of disease genes that map to the chromosome: Links are also given to the Genes and Disease Web site, OMIM, and OMIM Morbid Map.

Links to references giving information on the chromosomal sequence: For example, the Entrez Genomes view for chromosome 22 gives a link to the full text of the paper by Dunham et al. (Nature (1999) 402, 489-95) that reports the completion of chromosome 22 sequencing.

To see the human chromosome views, go to, DW

NCBI News | Winter 2000