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UGID:382855     UniGene Rn.11082     Rattus norvegicus (Norway rat)   Th
Tyrosine hydroxylase (Th)

Norway rat protein-coding gene Th. Represented by 47 ESTs from 10 cDNA libraries. EST representation biased toward adrenal gland. Corresponds to reference sequence NM_012740.3. [UniGene 382855 - Rn.11082]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036872.1 Th gene product R. norvegicus 100.0 497
NP_033403.1 Th gene product M. musculus 97.8 497
NP_000351.2 TH gene product H. sapiens 91.9 496
NP_001091392.1 tyrosine hydroxylase X. laevis 80.0 488
NP_571224.1 th gene product D. rerio 78.7 488
NP_476897.1 pale, isoform A D. melanogaster 63.5 457
NP_001254184.1 Protein PAH-1, isoform b C. elegans 60.1 421
XP_001690034.1 aromatic amino acid hydroxylase-related protein C. reinhardtii 49.7 308
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
NP_001002966.1 TH gene product C. lupus familiaris 92.7 494
XP_002799487.1 PREDICTED: tyrosine 3-monooxygenase-like, partial M. mulatta 92.3 453

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adrenal gland [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: adrenal gland; mixed; brain; uncharacterized tissue; prostate
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q41
UniSTS entry: PMC18740P1
UniSTS entry: M69200
UniSTS entry: Th
UniSTS entry: Tmem50b
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

M10244.1 Rat tyrosine hydroxylase mRNA, complete cds PA
NM_012740.3 Rattus norvegicus tyrosine hydroxylase (Th), mRNA PA

EST sequences (10 of 47) [Show all sequences]

H34982.1 Clone RPCCG77 adrenal gland P
H35036.1 Clone RPNBS43 adrenal gland P
AA684589.1 Clone RPCAD21 adrenal gland 5' read P
AA684782.1 Clone RPCAI70 adrenal gland 5' read
AA684934.1 Clone RPCAT11 adrenal gland 5' read P
AA685017.1 Clone RPCAW28 adrenal gland 5' read P
AA685049.1 Clone RPCAX48 adrenal gland 5' read P
AA685388.1 Clone RPCBK20 adrenal gland 5' read P
AA685597.1 Clone RPCBZ12 adrenal gland 5' read P
AA685648.1 Clone RPCCC38 adrenal gland 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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