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UGID:382283     UniGene Rn.10247     Rattus norvegicus (Norway rat)   Stat3
Signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3)

Norway rat protein-coding gene Stat3. Represented by 125 ESTs from 63 cDNA libraries. Corresponds to reference sequence NM_012747.2. [UniGene 382283 - Rn.10247]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_998824.1 Stat3 gene product M. musculus 100.0 769
NP_036879.1 Stat3 gene product R. norvegicus 100.0 769
XP_004012974.1 PREDICTED: signal transducer and activator of transcription 3 O. aries 100.0 721
XP_001109505.2 PREDICTED: signal transducer and activator of transcription 3 isoform 1 M. mulatta 99.9 769
XP_003913116.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 P. anubis 99.9 769
XP_001165417.2 PREDICTED: signal transducer and activator of transcription 3 isoform 2 P. troglodytes 99.9 769
NP_644805.1 STAT3 gene product H. sapiens 99.9 769
NP_001038045.1 STAT3 gene product S. scrofa 99.9 769
XP_002719441.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 O. cuniculus 99.9 769
XP_003362604.1 PREDICTED: signal transducer and activator of transcription 3 isoform 2 E. caballus 99.9 768
NP_001012689.2 STAT3 gene product B. taurus 99.7 769
XP_001363772.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 M. domestica 99.6 769
XP_548090.2 PREDICTED: signal transducer and activator of transcription 3 isoform 1 C. lupus familiaris 99.6 768
NP_001090202.1 signal transducer and activator of transcription 3.1 X. laevis 98.2 768
NP_571554.1 stat3 gene product D. rerio 92.9 803
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_003213184.1 PREDICTED: signal transducer and activator of transcription 3-like M. gallopavo 98.8 770
XP_003222526.1 PREDICTED: signal transducer and activator of transcription 3-like A. carolinensis 98.6 770

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; vibrissa; cervix; connective tissue; ovary; embryonic tissue; brain; pituitary gland; eye; adipose tissue; lung; kidney; uncharacterized tissue; liver; mixed; heart; prostate; spleen; muscle; inner ear; thymus; pancreas; colon; nerve; small intestine; dorsal root ganglion; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q32.1
UniSTS entry: RH143302
UniSTS entry: RH94819
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

X91810.1 R.norvegicus mRNA for Stat3 protein P
NM_012747.2 Rattus norvegicus signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3), mRNA PA
BC087025.1 Rattus norvegicus signal transducer and activator of transcription 3, mRNA (cDNA clone MGC:93551 IMAGE:7110655), complete cds PA
FQ225489.1 Rattus norvegicus TL0AEA4YO13 mRNA sequence P
FQ223504.1 Rattus norvegicus TL0ADA10YH23 mRNA sequence P
GU477503.1 Rattus norvegicus strain W signal transducer and activator of transcription 3 (Stat3) mRNA, 3' UTR A
GU477504.1 Rattus norvegicus strain W signal transducer and activator of transcription 3 (Stat3) mRNA, 3' UTR A

EST sequences (10 of 125) [Show all sequences]

H32832.1 adrenal gland 5' read
AA957927.1 Clone UI-R-E1-fv-d-04-0-UI 3' read A
AA963923.1 Clone UI-R-E1-ga-c-05-0-UI 3' read A
AI008865.1 Clone REMBE54 embryonic tissue 3' read
AI012356.1 Clone RPLAW15 placenta 3' read
AI014104.1 Clone RSPBF05 spleen 3' read
AI014152.1 Clone RSPBF69 spleen 3' read
AI045179.1 Clone UI-R-C1-kk-g-12-0-UI mixed 3' read A
AI059916.1 Clone UI-R-C1-kr-c-02-0-UI mixed 3' read A
AI111418.1 Clone UI-R-Y0-mk-h-05-0-UI eye 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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