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UGID:257603     UniGene Mm.4418     Mus musculus (mouse)   Cacna1s
Calcium channel, voltage-dependent, L type, alpha 1S subunit (Cacna1s)

Mouse protein-coding gene Cacna1s. Represented by 26 ESTs from 17 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 257603 - Mm.4418]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001074492.1 Cacna1s gene product M. musculus 100.0 1851
NP_000060.2 CACNA1S gene product H. sapiens 93.6 1872
NP_999891.1 cacna1sb gene product D. rerio 70.5 1812
NP_723953.1 Ca[2+]-channel protein alpha[[1]] subunit D, isoform D D. melanogaster 61.9 1573
NP_741442.1 Protein EGL-19, isoform a C. elegans 61.7 1614
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
NP_446325.1 Cacna1s gene product R. norvegicus 97.5 1849
XP_848685.3 PREDICTED: voltage-dependent L-type calcium channel subunit alpha-1S isoform 2 C. lupus familiaris 94.5 1872

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; muscle; mixed; heart; embryonic tissue; lung; salivary gland; uncharacterized tissue; mammary gland; brain; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1 F|1 59.55 cM
UniSTS entry: Chr 1 AW493108
UniSTS entry: Cacna1s
UniSTS entry: Cacna1s
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

M57976.1 Mouse skeletal muscle L-type calcium channel (CaCh1b) mRNA, partial cds P
M57968.1 Mouse skeletal muscle L-type calcium channel mRNA, partial cds P
BC094499.1 Mus musculus calcium channel, voltage-dependent, L type, alpha 1S subunit, mRNA (cDNA clone IMAGE:4925543) PA
AK142239.1 Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330018B03 product:calcium channel, voltage-dependent, L type, alpha 1S subunit, full insert sequence P
AK143541.1 Mus musculus 12 days embryo whole body cDNA, RIKEN full-length enriched library, clone:E970023J21 product:calcium channel, voltage-dependent, L type, alpha 1S subunit, full insert sequence P
NM_001081023.1 Mus musculus calcium channel, voltage-dependent, L type, alpha 1S subunit (Cacna1s), transcript variant 2, mRNA P
BC134369.1 Mus musculus calcium channel, voltage-dependent, L type, alpha 1S subunit, mRNA (cDNA clone IMAGE:40054822), complete cds P
L06234.1 Mus musculus dihydropyridine sensitive skeletal muscle calcium channel mRNA, complete cds P
NM_014193.2 Mus musculus calcium channel, voltage-dependent, L type, alpha 1S subunit (Cacna1s), transcript variant 1, mRNA P

EST sequences (10 of 26) [Show all sequences]

BY366917.1 Clone E970023J21 embryonic tissue 3' read
BX637817.1 Clone LIONp462G0245 uncharacterized tissue 3' read A
CR757020.1 Clone P0AC001ZG02 muscle P
CR757812.1 Clone P0AC001ZG02 muscle P
CJ065185.1 Clone D330018B03 heart 5' read P
EL607635.1 Clone nbk31f09 eye
AA048600.1 Clone IMAGE:477822 embryonic tissue 5' read
AA855202.1 Clone IMAGE:1260171 heart 5' read
AI463987.1 Clone IMAGE:1260171 heart 5' read
AW493108.1 Clone UI-M-BH3-atz-e-03-0-UI mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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