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UGID:333334     UniGene Mm.246688     Mus musculus (mouse)   Ezh2
Enhancer of zeste homolog 2 (Drosophila) (Ezh2)

Mouse protein-coding gene Ezh2. Represented by 355 ESTs from 138 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 333334 - Mm.246688]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031997.2 Ezh2 gene product M. musculus 100.0 745
NP_001128451.1 Ezh2 gene product R. norvegicus 100.0 745
NP_001190176.1 EZH2 gene product H. sapiens 99.2 745
NP_001083886.1 histone-lysine N-methyltransferase EZH2 X. laevis 96.4 747
NP_001070747.1 ezh2 gene product D. rerio 91.8 759
NP_001137932.1 enhancer of zeste, isoform B D. melanogaster 71.2 757
NP_496992.3 Protein MES-2 C. elegans 53.4 204
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
XP_003432121.1 PREDICTED: histone-lysine N-methyltransferase EZH2 C. lupus familiaris 99.5 745
XP_001504679.1 PREDICTED: histone-lysine N-methyltransferase EZH2 isoform 1 E. caballus 99.5 745

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; ovary; thymus; fertilized ovum; mammary gland; eye; bone marrow; brain; mixed; extraembryonic tissue; pituitary gland; heart; uncharacterized tissue; skin; spleen; testis; blood; intestine; kidney; adipose tissue; lung; lymph node; stomach; bone; liver; pancreas; connective tissue; nasopharynx; inner ear; joint; prostate; molar
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6 B|6 22.92 cM
UniSTS entry: Chr 6 Ezh2
UniSTS entry: Chr 6 U52951
UniSTS entry: Chr 6 AW554728
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AK089716.1 Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830010H11 product:unclassifiable, full insert sequence
AK086532.1 Mus musculus 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930035K12 product:unclassifiable, full insert sequence
BC079538.1 Mus musculus enhancer of zeste homolog 2 (Drosophila), mRNA (cDNA clone MGC:90723 IMAGE:6817366), complete cds PA
AK198464.1 Mus musculus cDNA, clone:Y1G0128E04, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000031698, based on BLAT search P
AK220174.1 Mus musculus mRNA for mKIAA4065 protein P
AK157853.1 Mus musculus erythroblast cDNA, RIKEN full-length enriched library, clone:K0C0026B09 product:enhancer of zeste homolog 2 (Drosophila), full insert sequence P
AK153835.1 Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920016A05 product:enhancer of zeste homolog 2 (Drosophila), full insert sequence P
NM_001146689.1 Mus musculus enhancer of zeste homolog 2 (Drosophila) (Ezh2), transcript variant 2, mRNA PA
U52951.1 Mus musculus putative transcriptional regulator mEnx-1 mRNA, complete cds PA
NM_007971.2 Mus musculus enhancer of zeste homolog 2 (Drosophila) (Ezh2), transcript variant 1, mRNA PA
BC003772.1 Mus musculus enhancer of zeste homolog 2 (Drosophila), mRNA (cDNA clone MGC:5969 IMAGE:3492110), complete cds PA
BC016391.1 Mus musculus enhancer of zeste homolog 2 (Drosophila), mRNA (cDNA clone MGC:5970 IMAGE:3586689), complete cds PA

EST sequences (10 of 355) [Show all sequences]

CA564947.1 Clone NIA:K0332A09_IMAGE:30057320 bone 5' read P
CA578870.2 Clone NIA:K0729E11_IMAGE:30076378 bone marrow 5' read P
BY005171.1 Clone F420001H15 spleen 5' read
BY030281.1 Clone I0C0008H03 embryonic tissue 5' read P
BY035017.1 Clone I530016M08 extraembryonic tissue 5' read P
BY035560.1 Clone I530019L21 extraembryonic tissue 5' read P
BY084343.1 Clone K630047N21 mixed 5' read
BY093522.1 Clone K630096H13 mixed 5' read
BY080632.1 Clone K630026F21 thymus 5' read P
BY097830.1 Clone K630118K04 mixed 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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