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UGID:258736     UniGene Mm.8534     Mus musculus (mouse)   Egfr
Epidermal growth factor receptor (Egfr)

Mouse protein-coding gene Egfr. Represented by 124 ESTs from 64 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 258736 - Mm.8534]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_997538.1 Egfr gene product M. musculus 100.0 1209
NP_005219.2 EGFR gene product H. sapiens 93.5 1209
NP_919405.1 egfra gene product D. rerio 72.8 1178
NP_001089061.1 v-erb-a erythroblastic leukemia viral oncogene homolog 4 precursor X. laevis 60.9 1246
NP_476758.1 epidermal growth factor receptor, isoform A D. melanogaster 48.2 1178
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
NP_113695.1 Egfr gene product R. norvegicus 97.4 1208
XP_001497780.2 PREDICTED: epidermal growth factor receptor E. caballus 94.2 1180

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; uncharacterized tissue; embryonic tissue; brain; bone marrow; ovary; skin; spleen; testis; mammary gland; vagina; mixed; pancreas; kidney; tongue; thymus; eye; extraembryonic tissue; lung; connective tissue; intestine; fertilized ovum; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11 A1-A4|11 9.41 cM
UniSTS entry: Chr 11 X78987
UniSTS entry: Egfr
UniSTS entry: Egfr
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AK087861.1 Mus musculus 2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330032E20 product:epidermal growth factor receptor, full insert sequence P
X59698.1 M.musculus mRNA for EGF-receptor P
Z12608.1 M.musculus mRNA encoding epidermal growth factor receptor P
NM_207655.2 Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA PA
AK163338.1 Mus musculus 2 cells egg cDNA, RIKEN full-length enriched library, clone:B020015L02 product:epidermal growth factor receptor, full insert sequence P
AK134262.1 Mus musculus 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930413O06 product:epidermal growth factor receptor, full insert sequence P
U03425.1 Mus musculus B6/C3 EGF receptor mRNA, complete cds P
L06864.1 Mus musculus epidermal growth factor receptor (EGFR) mRNA, partial cds P
X78987.1 M.musculus (BALB/c) Epidermal Growth Factor Receptor mRNA P
NM_007912.4 Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA P
AF124513.1 Mus musculus epidermal growth factor receptor (Egfr) mRNA, alternatively spliced, complete cds PA
AF275367.1 Mus musculus epidermal growth factor receptor (Egfr) mRNA, complete cds PA
AK014017.1 Mus musculus 13 days embryo head cDNA, RIKEN full-length enriched library, clone:3110007E23 product:EPIDERMAL GROWTH FACTOR RECEPTOR (FRAGMENT) homolog [Mus musculus], full insert sequence
AK004944.1 Mus musculus adult male liver cDNA, RIKEN full-length enriched library, clone:1300008I23 product:epidermal growth factor receptor, full insert sequence P
AK004911.1 Mus musculus adult male liver cDNA, RIKEN full-length enriched library, clone:1300005M11 product:epidermal growth factor receptor, full insert sequence P
AK004883.1 Mus musculus adult male liver cDNA, RIKEN full-length enriched library, clone:1300003K07 product:epidermal growth factor receptor, full insert sequence P
AF277898.1 Mus musculus truncated epidermal growth factor receptor (Egfr) mRNA, partial cds; alternatively spliced P
BC023729.1 Mus musculus epidermal growth factor receptor, mRNA (cDNA clone MGC:36101 IMAGE:5351807), complete cds PA

EST sequences (10 of 124) [Show all sequences]

BY087263.1 Clone K630065B11 testis 5' read
BY322278.1 Clone L030013F08 connective tissue 5' read
BY361990.1 Clone 9930018D06 vagina 3' read P
BY361994.1 Clone 9930031N03 vagina 3' read P
BY452795.1 Clone K630065B11 testis 3' read A
BY673623.1 Clone K820032E02 embryonic tissue 3' read
BY705088.1 Clone 1300003K07 liver 5' read P
BY705116.1 Clone 1300005M11 liver 5' read P
BY705153.1 Clone 1300008I23 liver 5' read P
BY725722.1 Clone B020015L02 embryonic tissue 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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