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UGID:257323     UniGene Mm.3830     Mus musculus (mouse)   Fpgs
Folylpolyglutamyl synthetase (Fpgs)

Mouse protein-coding gene Fpgs. Represented by 321 ESTs from 118 cDNA libraries. Corresponds to reference sequence NM_010236.2. [UniGene 257323 - Mm.3830]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_034366.2 Fpgs gene product M. musculus 100.0 586
NP_004948.4 folylpolyglutamate synthase, mitochondrial isoform a precursor H. sapiens 87.2 586
NP_998602.1 fpgs gene product D. rerio 69.2 564
NP_014884.1 tetrahydrofolate synthase S. cerevisiae 50.0 444
NP_001031840.1 DHFS-FPGS homolog B A. thaliana 48.6 506
XP_964808.2 hypothetical protein NCU00892 N. crassa 48.5 396
NP_572814.1 CG2543 D. melanogaster 46.8 468
NP_001022548.1 Protein F25B5.6, isoform c C. elegans 46.4 476
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
NP_001139597.2 folylpolyglutamate synthase precursor R. norvegicus 93.9 586
XP_003911961.1 PREDICTED: folylpolyglutamate synthase, mitochondrial isoform 1 P. anubis 86.4 586

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; mammary gland; thyroid; ovary; kidney; liver; lung; thymus; brain; mixed; bone marrow; extraembryonic tissue; skin; inner ear; spleen; pituitary gland; testis; muscle; eye; joint; fertilized ovum; uncharacterized tissue; pancreas; epididymis; bladder; dorsal root ganglion; heart; oviduct; salivary gland; nasopharynx; uterus; intestine
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2 B|2 22.09 cM
UniSTS entry: Chr 2 Fpgs
UniSTS entry: Chr 2 RH124683
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AK041952.1 Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630048J24 product:folylpolyglutamyl synthetase, full insert sequence P
NM_010236.2 Mus musculus folylpolyglutamyl synthetase (Fpgs), nuclear gene encoding mitochondrial protein, mRNA PA
AK193619.1 Mus musculus cDNA, clone:Y1G0112N20, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000028148, based on BLAT search P
AK184103.1 Mus musculus cDNA, clone:Y0G0128K09, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000028148, based on BLAT search P
AK181115.1 Mus musculus cDNA, clone:Y0G0116P21, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000028148, based on BLAT search P
AK157040.1 Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830114J03 product:folylpolyglutamyl synthetase, full insert sequence P
U32197.1 Mus musculus folylpolyglutamate synthetase mRNA, nuclear gene encoding cytosolic and mitochondrial protein, complete cds P
U33557.1 Mus musculus folylpolyglutamate synthetase precursor (Fpgs) mRNA, complete cds PA
BC005484.1 Mus musculus folylpolyglutamyl synthetase, mRNA (cDNA clone MGC:7296 IMAGE:3485401), complete cds PA

EST sequences (10 of 321) [Show all sequences]

BY009746.1 Clone G730015D03 lung 5' read P
BY010877.1 Clone G730022N07 lung 5' read P
BY011202.1 Clone G730024G19 lung 5' read P
BY012342.1 Clone G730032I04 lung 5' read P
BY012533.1 Clone G730033J01 lung 5' read P
BY014515.1 Clone G730046N09 lung 5' read P
BY014806.1 Clone G730048A16 lung 5' read P
BY015444.1 Clone G730050N16 lung 5' read P
BY018432.1 Clone G830028F12 mammary gland 5' read P
BY018591.1 Clone G830029B13 mammary gland 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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