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UGID:1098952     UniGene Mm.299916     Mus musculus (mouse)   Pcsk4
Proprotein convertase subtilisin/kexin type 4 (Pcsk4)

Mouse protein-coding gene Pcsk4. Represented by 24 ESTs from 21 cDNA libraries. Corresponds to reference sequence NM_008793.2. [UniGene 1098952 - Mm.299916]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_032819.1 Pcsk4 gene product M. musculus 100.0 654
NP_060043.2 proprotein convertase subtilisin/kexin type 4 precursor H. sapiens 80.4 675
NP_001089023.1 proprotein convertase subtilisin/kexin type 4 X. laevis 63.7 644
NP_001038571.1 furin A precursor D. rerio 56.2 673
NP_492974.2 Protein KPC-1, isoform a C. elegans 50.6 593
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
NP_598243.1 Pcsk4 gene product R. norvegicus 94.0 653
XP_585571.3 PREDICTED: proprotein convertase subtilisin/kexin type 4, partial B. taurus 86.8 568

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; spleen; kidney; mammary gland; inner ear; brain; testis; mixed; lung; pituitary gland; liver; spinal cord; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10 C1|10 39.72 cM
UniSTS entry: Chr 10 L21221
UniSTS entry: Pcsk4
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

NM_008793.2 Mus musculus proprotein convertase subtilisin/kexin type 4 (Pcsk4), mRNA P
D01093.1 Mus musculus mRNA for PC4, complete cds P

EST sequences (10 of 24) [Show all sequences]

BY100288.1 Clone K630131E14 mixed 5' read P
BY231211.1 Clone F930018I23 inner ear 5' read
BY716542.1 Clone 4933421J06 testis 5' read P
CF169617.1 Clone NIA:B0816A10_IMAGE:30468969 kidney 5' read P
BX636559.1 Clone LIONp462F0369 uncharacterized tissue 3' read A
CJ068296.1 Clone F430203L01 spleen 5' read
AI120910.1 Clone IMAGE:1383450 mammary gland 5' read
AV005120.1 Clone 0710008O07 brain
AI834937.1 Clone UI-M-AN1-afe-h-12-0-UI brain 3' read A
AW120673.1 Clone UI-M-BH2.3-anz-h-11-0-UI mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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