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UGID:879379     UniGene Mm.277779     Mus musculus (mouse)   Parp1
Poly (ADP-ribose) polymerase family, member 1 (Parp1)

Mouse protein-coding gene Parp1. Represented by 1122 ESTs from 250 cDNA libraries. Corresponds to reference sequence NM_007415.2. [UniGene 879379 - Mm.277779]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031441.2 Parp1 gene product M. musculus 100.0 1013
NP_001609.2 PARP1 gene product H. sapiens 96.0 1013
NP_001081571.1 poly [ADP-ribose] polymerase 1 X. laevis 81.4 1006
NP_001038407.1 poly [ADP-ribose] polymerase 1 D. rerio 78.1 1012
NP_001104452.1 Poly-(ADP-ribose) polymerase, isoform B D. melanogaster 52.2 990
NP_850165.1 Poly [ADP-ribose] polymerase 1 A. thaliana 49.2 979
XP_960982.2 hypothetical protein NCU08852 N. crassa 48.8 465
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
NP_037195.1 Parp1 gene product R. norvegicus 98.7 1013
XP_001090984.1 PREDICTED: poly [ADP-ribose] polymerase 1 isoform 4 M. mulatta 96.1 1013

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; mixed; bone marrow; eye; skin; mammary gland; kidney; testis; extraembryonic tissue; lung; heart; thymus; uncharacterized tissue; pancreas; bone; liver; ovary; spleen; vagina; spinal cord; joint; bladder; blood; pituitary gland; adrenal gland; intestine; dorsal root ganglion; oviduct; salivary gland; inner ear; sympathetic ganglion; connective tissue; lymph node; fertilized ovum; stomach; molar; nasopharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1 H5|1 84.44 cM
UniSTS entry: Chr 1 RH126937
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK088679.1 Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430023G15 product:POLY [ADP-RIBOSE] POLYMERASE-1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-RIBOSYLTRANSFERASE-1) (POLY[ADP-RIBOSE] SYNTHETASE-1) homolog ... P
AK030889.1 Mus musculus adult male thymus cDNA, RIKEN full-length enriched library, clone:5830444G22 product:SIMILAR TO ADP-RIBOSYLTRANSFERASE (NAD+, POLY (ADP-RIBOSE) POLYMERASE) [Mus musculus], full insert sequence P
AK028042.1 Mus musculus adult male lung cDNA, RIKEN full-length enriched library, clone:1200004M19 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK210311.1 Mus musculus cDNA, clone:Y2G0117P19, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027777, based on BLAT search P
AK204155.1 Mus musculus cDNA, clone:Y1G0147H13, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027777, based on BLAT search P
AK202655.1 Mus musculus cDNA, clone:Y1G0142E24, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027777, based on BLAT search
AK189836.1 Mus musculus cDNA, clone:Y0G0150O06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027777, based on BLAT search
AK177119.1 Mus musculus cDNA, clone:Y0G0101K16, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027777, based on BLAT search
AK152360.1 Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830066O09 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK167699.1 Mus musculus 14 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I530028O16 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK159433.1 Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420019P03 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK135977.1 Mus musculus in vitro fertilized eggs cDNA, RIKEN full-length enriched library, clone:7420443K22 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK146677.1 Mus musculus 17 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I920040M20 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK169326.1 Mus musculus 17 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I920184D05 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK166104.1 Mus musculus lung RCB-0558 LLC cDNA, RIKEN full-length enriched library, clone:G730039G24 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
AK165158.1 Mus musculus 8 cells embryo 8 cells cDNA, RIKEN full-length enriched library, clone:E860006E14 product:ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1, full insert sequence P
NM_007415.2 Mus musculus poly (ADP-ribose) polymerase family, member 1 (Parp1), mRNA PA
AF126717.1 Mus musculus msPARP mRNA, complete cds P
BC012041.1 Mus musculus poly (ADP-ribose) polymerase family, member 1, mRNA (cDNA clone MGC:6498 IMAGE:2648390), complete cds PA

EST sequences (10 of 1122) [Show all sequences]

CA580220.1 Clone NIA:K0748E06_IMAGE:30078197 bone marrow 5' read P
CA749279.1 Clone IMAGE:6831448 brain 5' read P
BY002143.1 Clone 6620406A09 ovary 5' read P
BY004962.1 Clone E860105A01 embryonic tissue 5' read P
BY010469.1 Clone G730020D24 lung 5' read
BY011541.1 Clone G730027J10 lung 5' read P
BY012229.1 Clone G730031I18 lung 5' read P
BY012577.1 Clone G730033N08 lung 5' read P
BY012581.1 Clone G730033N14 lung 5' read P
BY012601.1 Clone G730033P19 lung 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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