NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:336580     UniGene Mm.249934     Mus musculus (mouse)   Stat3
Signal transducer and activator of transcription 3 (Stat3)

Mouse protein-coding gene Stat3. Represented by 685 ESTs from 186 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 336580 - Mm.249934]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_998824.1 Stat3 gene product M. musculus 100.0 769
NP_036879.1 Stat3 gene product R. norvegicus 100.0 769
XP_001109505.2 PREDICTED: signal transducer and activator of transcription 3 isoform 1 M. mulatta 100.0 769
XP_003913116.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 P. anubis 100.0 769
NP_644805.1 STAT3 gene product H. sapiens 100.0 769
NP_001038045.1 STAT3 gene product S. scrofa 100.0 769
NP_001012689.2 STAT3 gene product B. taurus 100.0 769
XP_002719441.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 O. cuniculus 100.0 769
XP_003362604.1 PREDICTED: signal transducer and activator of transcription 3 isoform 2 E. caballus 100.0 768
XP_004012974.1 PREDICTED: signal transducer and activator of transcription 3 O. aries 100.0 721
XP_001363772.1 PREDICTED: signal transducer and activator of transcription 3 isoform 1 M. domestica 99.9 769
XP_548090.2 PREDICTED: signal transducer and activator of transcription 3 isoform 1 C. lupus familiaris 99.9 768
NP_001090202.1 signal transducer and activator of transcription 3.1 X. laevis 98.7 768
NP_571554.1 stat3 gene product D. rerio 93.7 805
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
XP_003213184.1 PREDICTED: signal transducer and activator of transcription 3-like M. gallopavo 99.3 770
XP_003222526.1 PREDICTED: signal transducer and activator of transcription 3-like A. carolinensis 99.1 770

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mammary gland; embryonic tissue; spleen; lung; mixed; uncharacterized tissue; pancreas; skin; brain; extraembryonic tissue; joint; heart; eye; intestine; liver; bone; bone marrow; ovary; thymus; blood; kidney; lymph node; thyroid; fertilized ovum; prostate; testis; inner ear; connective tissue; bladder; dorsal root ganglion; spinal cord; other; muscle; salivary gland; epididymis; nasopharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11 D|11 63.82 cM
UniSTS entry: Chr 11 AW109958 [Map Viewer]
UniSTS entry: Stat3
UniSTS entry: Chr 9 D10Mit157.2 [Map Viewer]
UniSTS entry: Chr 11 PMC303338P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

AK079406.1 Mus musculus adult male bone cDNA, RIKEN full-length enriched library, clone:9830127M23 product:signal transducer and activator of transcription 3, full insert sequence
AY299490.1 Mus musculus strain NOD/LtJ signal transducer and activator of transcription 3 (Stat3) mRNA, complete cds P
AY299489.1 Mus musculus strain C57BL/6J signal transducer and activator of transcription 3 (Stat3) mRNA, complete cds P
NM_213660.2 Mus musculus signal transducer and activator of transcription 3 (Stat3), transcript variant 2, mRNA P
NM_213659.2 Mus musculus signal transducer and activator of transcription 3 (Stat3), transcript variant 1, mRNA P
AK196867.1 Mus musculus cDNA, clone:Y1G0123E05, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000004142, based on BLAT search P
AK193746.1 Mus musculus cDNA, clone:Y1G0113D20, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000004142, based on BLAT search P
AK192951.1 Mus musculus cDNA, clone:Y1G0110H19, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000004142, based on BLAT search
AK192932.1 Mus musculus cDNA, clone:Y1G0110G16, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000004142, based on BLAT search P
AK184281.1 Mus musculus cDNA, clone:Y0G0129F22, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000004142, based on BLAT search
AK153005.1 Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830112K17 product:signal transducer and activator of transcription 3, full insert sequence P
AK145486.1 Mus musculus blastocyst blastocyst cDNA, RIKEN full-length enriched library, clone:I1C0004F14 product:signal transducer and activator of transcription 3, full insert sequence P
AK161906.1 Mus musculus adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330559I15 product:signal transducer and activator of transcription 3, full insert sequence
AK171827.1 Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830013C20 product:signal transducer and activator of transcription 3, full insert sequence
AK153472.1 Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830164K23 product:signal transducer and activator of transcription 3, full insert sequence P
AK153170.1 Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830125P20 product:signal transducer and activator of transcription 3, full insert sequence
U06922.1 Mus musculus signal transducer and activator of transcription (Stat3) mRNA, complete cds PA
L29278.1 Mus musculus acute phase response factor (APRF) gene, complete cds P
U08378.1 Mus musculus acute phase response factor (APRF) mRNA, complete cds P
U30709.1 Mus musculus Stat3B mRNA, complete cds PA
AK004083.1 Mus musculus 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110034C02 product:signal transducer and activator of transcription 3, full insert sequence
BC003806.1 Mus musculus signal transducer and activator of transcription 3, mRNA (cDNA clone MGC:6089 IMAGE:3593588), complete cds PA
BC019168.1 Mus musculus signal transducer and activator of transcription 3, mRNA (cDNA clone MGC:29120 IMAGE:4923137), complete cds PA
NM_011486.4 Mus musculus signal transducer and activator of transcription 3 (Stat3), transcript variant 3, mRNA P
BC037688.1 Mus musculus signal transducer and activator of transcription 3, mRNA (cDNA clone IMAGE:3665873), complete cds PA

EST sequences (10 of 685) [Show all sequences]

CA564914.1 Clone NIA:K0331F08_IMAGE:30057283 bone 5' read P
CA566161.1 Clone NIA:K0346H08_IMAGE:30058747 bone 5' read P
CA566258.1 Clone NIA:K0349C02_IMAGE:30058969 bone 5' read P
CA570252.1 Clone NIA:K0504A08_IMAGE:30064231 bone marrow 5' read P
CA749654.1 Clone IMAGE:6831978 brain 5' read P
BY007047.1 Clone G430011C24 mixed 5' read P
BY008495.1 Clone G630018J24 other 5' read
BY013150.1 Clone G730037A09 lung 5' read P
BY021132.1 Clone G830046A16 mammary gland 5' read
BY024375.1 Clone G930022M16 mammary gland 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help