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UGID:335777     UniGene Mm.249131     Mus musculus (mouse)   Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (Pfkfb1)

Mouse protein-coding gene Pfkfb1. Represented by 42 ESTs from 27 cDNA libraries. Corresponds to reference sequence NM_008824.2. [UniGene 335777 - Mm.249131]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_032850.1 Pfkfb1 gene product M. musculus 100.0 447
NP_001258733.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2 H. sapiens 94.4 448
NP_001088535.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 X. laevis 84.0 469
XP_002666487.2 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-like D. rerio 82.1 463
NP_728249.1 6-phosphofructo-2-kinase, isoform A D. melanogaster 66.9 432
NP_491529.2 Protein Y110A7A.6, isoform a C. elegans 59.0 441
XP_958926.1 fructose-2,6-bisphosphatase N. crassa 52.9 418
NP_012380.1 Fbp26p S. cerevisiae 52.0 421
NP_172191.1 fructose-2,6-bisphosphatase A. thaliana 49.6 387
XP_001698836.1 hypothetical protein CHLREDRAFT_121054 C. reinhardtii 47.6 392
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
NP_001257992.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2 R. norvegicus 99.2 468
XP_004022101.1 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 O. aries 96.4 470

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; liver; ovary; testis; mammary gland; connective tissue; mixed; brain; bone marrow; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: X|X F2
UniSTS entry: RH130115
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AY974594.1 Mus musculus 6-phosphofructo-2-kinase/fructose-26-biphosphatase 1-like (Pfkfb1) mRNA, partial sequence P
AK132629.1 Mus musculus 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4833435C23 product:6-phosphofructo-2-kinase/ fructose-2,6-biphosphatase 1, full insert sequence P
NM_008824.2 Mus musculus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (Pfkfb1), mRNA P
BC132563.1 Mus musculus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, mRNA (cDNA clone MGC:164194 IMAGE:40130840), complete cds P
BC132561.1 Mus musculus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, mRNA (cDNA clone MGC:164192 IMAGE:40130838), complete cds P
X98848.1 M.musculus mRNA for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, clone 500bC6 P

EST sequences (10 of 42) [Show all sequences]

BY310986.1 Clone I320017I19 uncharacterized tissue 5' read
BY320622.1 Clone L030002F08 connective tissue 5' read
BY320998.1 Clone L030004K19 connective tissue 5' read
BY327962.1 Clone L030044N20 connective tissue 5' read
BY701482.1 Clone L030002F08 connective tissue 3' read
BY701847.1 Clone L030004K19 connective tissue 3' read P
CA980058.1 Clone IMAGE:30145274 embryonic tissue 5' read P
CB525865.1 Clone IMAGE:6848307 brain 5' read P
BX522768.1 Clone IMAGp998J233826_;_IMAGE:1511542 mammary gland PA
CF907440.1 Clone NIA:A0510E10_IMAGE:30743769 bone marrow 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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