NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:260688     UniGene Mm.21158     Mus musculus (mouse)   Mtor
Mechanistic target of rapamycin (serine/threonine kinase) (Mtor)

Mouse protein-coding gene Mtor. Represented by 447 ESTs from 110 cDNA libraries. Corresponds to reference sequence NM_020009.2. [UniGene 260688 - Mm.21158]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_064393.2 Mtor gene product M. musculus 100.0 2548
NP_063971.1 Mtor gene product R. norvegicus 99.8 2548
NP_004949.1 MTOR gene product H. sapiens 99.6 2548
XP_002694089.1 PREDICTED: serine/threonine-protein kinase mTOR B. taurus 99.5 2550
XP_001492401.1 PREDICTED: serine/threonine-protein kinase mTOR E. caballus 99.5 2549
NP_001138927.1 MTOR gene product O. aries 99.5 2549
NP_001070679.2 mtor gene product D. rerio 93.6 2513
NP_524891.1 target of rapamycin, isoform A D. melanogaster 64.2 2468
XP_960570.1 phosphatidylinositol 3-kinase tor2 N. crassa 51.3 2462
NP_175425.2 FKBP12-rapamycin complex-associated protein A. thaliana 50.4 2452
NP_012600.1 Tor1p S. cerevisiae 48.3 2397
XP_001697578.1 target of rapamycin, growth-regulatory PI3K-like protein kinase C. reinhardtii 48.3 1652
NP_491552.2 Protein LET-363, isoform b C. elegans 45.0 2643
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_535407.3 PREDICTED: serine/threonine-protein kinase mTOR isoform 1 C. lupus familiaris 99.5 2545
XP_003127632.3 PREDICTED: serine/threonine-protein kinase mTOR S. scrofa 99.4 2547

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; embryonic tissue; extraembryonic tissue; mammary gland; eye; kidney; testis; inner ear; pancreas; thymus; spleen; uncharacterized tissue; ovary; connective tissue; blood; tongue; pineal gland; heart; uterus; lung; thyroid; salivary gland; intestine; molar; skin; liver; sympathetic ganglion
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4 E1|4 78.76 cM
UniSTS entry: Chr 4 RH134710
UniSTS entry: Chr 4 AI327068
UniSTS entry: Chr 4 MARC_7131-7132:996687522:1
UniSTS entry: Chr 4 MARC_17911-17912:1025019877:1
UniSTS entry: Chr 4 PMC299869P1
UniSTS entry: Mtor
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC043920.1 Mus musculus FK506 binding protein 12-rapamycin associated protein 1, mRNA (cDNA clone IMAGE:5064192), complete cds PA
AK012031.1 Mus musculus 10 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2610315D21 product:FK506 binding protein 12-rapamycin associated protein 1, full insert sequence P
BC021454.1 Mus musculus FK506 binding protein 12-rapamycin associated protein 1, mRNA (cDNA clone IMAGE:5043381), with apparent retained intron PA
AK143381.1 Mus musculus 2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330020J06 product:FK506 binding protein 12-rapamycin associated protein 1, full insert sequence P
AK172584.1 Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830216D04 product:FK506 binding protein 12-rapamycin associated protein 1, full insert sequence P
AK158715.1 Mus musculus visual cortex cDNA, RIKEN full-length enriched library, clone:K230305B11 product:Warning: possibly chimeric clone, full insert sequence PA
BC112904.1 Mus musculus FK506 binding protein 12-rapamycin associated protein 1, mRNA (cDNA clone MGC:118056 IMAGE:6465126), complete cds PA
AF152838.1 Mus musculus FKBP-rapamycin-associated protein FRAP mRNA, complete cds PA
NM_020009.2 Mus musculus mechanistic target of rapamycin (serine/threonine kinase) (Mtor), mRNA PA

EST sequences (10 of 447) [Show all sequences]

BY099069.1 Clone K630125N03 testis 5' read
BY113065.1 Clone L430013D05 embryonic tissue 5' read P
BY113195.1 Clone L430014I01 embryonic tissue 5' read P
BY204855.1 Clone F730215I22 skin 5' read P
BY235762.1 Clone F930043I10 inner ear 5' read P
BY246440.1 Clone K230305B11 brain 5' read P
BY323432.1 Clone L030019F05 connective tissue 5' read P
BY326682.1 Clone L030037H02 connective tissue 5' read P
BY366784.1 Clone E970019F02 embryonic tissue 3' read
BY569844.1 Clone F830216D04 spleen 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help