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UGID:2723832     UniGene Hs.654514     Homo sapiens (human)   PTPRC
Protein tyrosine phosphatase, receptor type, C (PTPRC)

Human protein-coding gene PTPRC. Represented by 585 ESTs from 152 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 2723832 - Hs.654514]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002829.3 PTPRC gene product H. sapiens 100.0 1305
XP_001141776.2 PREDICTED: receptor-type tyrosine-protein phosphatase C isoform 6 P. troglodytes 99.6 1305
NP_001104786.2 Ptprc gene product M. musculus 81.7 1292
XP_687562.4 PREDICTED: receptor-type tyrosine-protein phosphatase C D. rerio 65.9 601
NP_001089394.1 protein tyrosine phosphatase, receptor type, E precursor X. laevis 48.2 280
NP_001021944.1 Protein PTP-3, isoform c C. elegans 48.2 195
NP_788502.1 protein tyrosine phosphatase 69D, isoform B D. melanogaster 47.2 286
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_003893396.1 PREDICTED: LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C P. anubis 93.7 1306
XP_003130644.3 PREDICTED: receptor-type tyrosine-protein phosphatase C S. scrofa 92.1 685

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; blood; lymph node; thymus; uncharacterized tissue; spleen; pharynx; kidney; brain; lung; mixed; vascular; ovary; intestine; tonsil; liver; muscle; stomach; uterus; pancreas; embryonic tissue; bone marrow; larynx; trachea; mammary gland; placenta; prostate; lymph; testis; skin; eye; bone; adrenal gland; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q31-q32
UniSTS entry: Chr 1 RH70956
UniSTS entry: Chr 1 RH68702
UniSTS entry: Chr 1 PTPRC_1163
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (24)

AK130573.1 Homo sapiens cDNA FLJ27063 fis, clone SPL01079
NM_002838.4 Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, mRNA PA
AY567999.1 Homo sapiens CD45 transcript variant (PTPRC) mRNA, partial cds, alternatively spliced P
AY429566.1 Homo sapiens PTPRCv_2 mRNA sequence; alternatively spliced
AY429565.1 Homo sapiens PTPRCv_1 mRNA sequence; alternatively spliced P
BC121086.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:40119796), complete cds
BC121087.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:40119797), complete cds
BC127657.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:40119800), complete cds
BC127656.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:40119799), complete cds
Y00062.1 Human mRNA for T200 leukocyte common antigen (CD45, LC-A) P
Y00638.1 Human mRNA for leukocyte common antigen (T200) P
BC148257.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:40119801), complete cds
AK292131.1 Homo sapiens cDNA FLJ76921 complete cds, highly similar to Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 2, mRNA P
AK310898.1 Homo sapiens cDNA, FLJ17940
AK308217.1 Homo sapiens cDNA, FLJ98165 P
AK307635.1 Homo sapiens cDNA, FLJ97583 P
NM_080921.3 Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 2, mRNA PA
AK299986.1 Homo sapiens cDNA FLJ53186 partial cds, highly similar to Leukocyte common antigen precursor (EC 3.1.3.48) P
AK303539.1 Homo sapiens cDNA FLJ61519 complete cds, highly similar to Leukocyte common antigen precursor (EC 3.1.3.48) P
BC031525.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:4385226), with apparent retained intron A
BC017863.1 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:4695712), complete cds A
BC014239.2 Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA (cDNA clone IMAGE:4565766), partial cds PA
NR_052021.1 Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 4, non-coding RNA A
NM_001267798.1 Homo sapiens protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 5, mRNA A

EST sequences (10 of 585) [Show all sequences]

AA974472.1 Clone IMAGE:1372118 lymph node 3' read P
AA904360.1 Clone IMAGE:1523530 mixed 3' read A
AA922184.1 Clone IMAGE:1544044 mixed 3' read
AI081674.1 Clone IMAGE:1632521 mammary gland 3' read
AI127665.1 Clone IMAGE:1710315 uterus 3' read A
CB044472.1 Clone IMAGE:3217729 intestine 5' read
AI151445.1 Clone IMAGE:1721333 uterus 3' read A
AI185650.1 Clone IMAGE:1743840 lung 3' read P
AI249443.1 Clone IMAGE:2000195 lymph node 3' read
CB157202.1 Clone L17N670205n1-7-E12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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