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UGID:2068050     UniGene Hs.599039     Homo sapiens (human)   MCAM
Melanoma cell adhesion molecule (MCAM)

Human protein-coding gene MCAM. Represented by 1222 ESTs from 277 cDNA libraries. Corresponds to reference sequence NM_006500.2. [UniGene 2068050 - Hs.599039]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006491.2 MCAM gene product H. sapiens 100.0 645
XP_001149681.2 PREDICTED: cell surface glycoprotein MUC18 P. troglodytes 99.5 645
NP_075548.2 Mcam gene product M. musculus 81.2 647
Other hits (2 of 8) [Show all]SpeciesId(%)Len(aa)
XP_003910875.1 PREDICTED: cell surface glycoprotein MUC18 P. anubis 98.3 645
XP_001917629.1 PREDICTED: LOW QUALITY PROTEIN: cell surface glycoprotein MUC18 E. caballus 89.9 625

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; vascular; placenta; uterus; lung; thymus; skin; mouth; kidney; testis; intestine; spleen; heart; trachea; ear; esophagus; bladder; stomach; embryonic tissue; uncharacterized tissue; mammary gland; prostate; umbilical cord; cervix; adipose tissue; adrenal gland; eye; connective tissue; pancreas; liver; ovary; mixed; pituitary gland; pharynx; bone marrow; thyroid; ganglia; muscle; parathyroid; bone; larynx; nerve; blood; amniotic fluid; lymph node
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.3
UniSTS entry: Chr 11 A002O48
UniSTS entry: MARC_15973-15974:1016732079:3
UniSTS entry: G15978
UniSTS entry: Chr 11 SGC35254 [Map Viewer]
UniSTS entry: STS-M29277
UniSTS entry: Chr 1 D11S3114
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF089868.1 Homo sapiens cell surface glycoprotein P1H12 precursor, mRNA, complete cds PA
BC056418.1 Homo sapiens melanoma cell adhesion molecule, mRNA (cDNA clone MGC:65073 IMAGE:6195486), complete cds PA
AK128335.1 Homo sapiens cDNA FLJ46477 fis, clone THYMU3025118, highly similar to Cell surface glycoprotein MUC18 precursor P
AK126303.1 Homo sapiens cDNA FLJ44324 fis, clone TRACH3002168, highly similar to Cell surface glycoprotein MUC18 precursor P
NM_006500.2 Homo sapiens melanoma cell adhesion molecule (MCAM), mRNA P
AJ297452.1 Homo sapiens partial mRNA for melanoma adhesion molecule (MCAM gene), short cytoplasmic tail isoform
AB209925.1 Homo sapiens mRNA for Melanoma cell adhesion molecule variant protein P
AK291571.1 Homo sapiens cDNA FLJ78619 complete cds, highly similar to Homo sapiens melanoma cell adhesion molecule (MCAM), mRNA P
AK312430.1 Homo sapiens cDNA, FLJ92775, highly similar to Homo sapiens melanoma cell adhesion molecule (MCAM), mRNA P
M29277.1 Human isolate JuSo MUC18 glycoprotein mRNA (3' variant), complete cds P
M28882.1 Human MUC18 glycoprotein mRNA, complete cds PA

EST sequences (10 of 1222) [Show all sequences]

AA987619.1 Clone IMAGE:1603398 lung 3' read
AA993017.1 Clone IMAGE:1622756 embryonic tissue 3' read A
AI031688.1 Clone IMAGE:1650107 parathyroid 3' read A
AI039157.1 Clone IMAGE:1657938 embryonic tissue 3' read A
AI041818.1 Clone IMAGE:1667704 parathyroid 3' read A
AI061054.1 Clone IMAGE:1699438 kidney 3' read
AI075739.1 Clone IMAGE:1676878 embryonic tissue 3' read A
R21191.1 Clone IMAGE:130299 placenta 5' read
AI088654.1 Clone IMAGE:1696216 uterus 3' read A
AI093248.1 Clone IMAGE:1695271 uterus 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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