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UGID:2061176     UniGene Hs.592165     Homo sapiens (human)   DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L)

Human protein-coding gene DNMT3L. Represented by 46 ESTs from 13 cDNA libraries. EST representation biased toward placenta; germ cell tumor. Corresponds to 2 reference sequences (different isoforms). [UniGene 2061176 - Hs.592165]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_037501.2 DNMT3L gene product H. sapiens 100.0 386
NP_001075164.1 Dnmt3l gene product M. musculus 70.7 372
NP_001018150.1 dnmt3ab gene product D. rerio 52.0 175
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_525483.2 PREDICTED: DNA (cytosine-5-)-methyltransferase 3-like P. troglodytes 99.5 386
XP_001118368.2 PREDICTED: DNA (cytosine-5-)-methyltransferase 3-like M. mulatta 95.3 386

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: placenta [show more like this]
germ cell tumor [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; uncharacterized tissue; testis; embryonic tissue; epididymis; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_175867.2 Homo sapiens DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L), transcript variant 2, mRNA PA
NM_013369.3 Homo sapiens DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L), transcript variant 1, mRNA PA
AF194032.1 Homo sapiens cytosine-5-methyltransferase 3-like protein (DNMT3L) mRNA, complete cds P
BC002560.2 Homo sapiens DNA (cytosine-5-)-methyltransferase 3-like, mRNA (cDNA clone MGC:1090 IMAGE:3138514), complete cds PA

EST sequences (10 of 46) [Show all sequences]

AI032151.1 Clone IMAGE:1611298 uncharacterized tissue 3' read
AI335740.1 Clone IMAGE:1948588 uncharacterized tissue 3' read P
AW014181.1 Clone IMAGE:2709627 uncharacterized tissue 3' read PA
AW393785.1 testis P
AW393793.1 testis P
CV028834.1 mixed 5' read P
BE278445.1 Clone IMAGE:3140282 placenta 5' read P
BE278718.1 Clone IMAGE:3505469 placenta 5' read P
BE280360.1 Clone IMAGE:3505157 placenta 5' read P
BE280451.1 Clone IMAGE:3505312 placenta 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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