NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:1351030     UniGene Hs.534293     Homo sapiens (human)   SERPINA3
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3)

Human protein-coding gene SERPINA3. Represented by 1753 ESTs from 277 cDNA libraries. Corresponds to reference sequence NM_001085.4. [UniGene 1351030 - Hs.534293]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001076.2 SERPINA3 gene product H. sapiens 100.0 422
NP_033278.2 Serpina3n gene product M. musculus 68.8 415
NP_001081358.1 alpha-1-antiproteinase precursor X. laevis 52.5 368
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_510145.2 PREDICTED: alpha-1-antichymotrypsin isoform 5 P. troglodytes 98.9 447
XP_001096947.2 PREDICTED: alpha-1-antichymotrypsin isoform 1 M. mulatta 92.4 447

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; pancreas; brain; mammary gland; eye; uncharacterized tissue; uterus; connective tissue; prostate; placenta; mixed; lung; skin; bladder; stomach; kidney; blood; testis; cervix; trachea; larynx; intestine; muscle; nerve; heart; pharynx; ascites; ovary; bone; pituitary gland; salivary gland; adrenal gland; esophagus; adipose tissue; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.1
UniSTS entry: Chr 14 RH1625 [Map Viewer]
UniSTS entry: Chr 14 RH91507
UniSTS entry: Chr 14 RH78280
UniSTS entry: Chr 14 SHGC-32982 [Map Viewer]
UniSTS entry: Chr 14 D14S845 [Map Viewer]
UniSTS entry: Chr 14 G31126
UniSTS entry: Chr 14 PMC27764P1
UniSTS entry: Chr 14 G31108
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF089747.1 Homo sapiens alpha-1-antichymotrypsin precursor, mRNA, partial cds P
NM_001085.4 Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3), mRNA PA
K01500.1 Human alpha-1-antichymotrypsin (AACT) mRNA, complete cds P
J05176.1 Human alpha-1-antichymotrypsin mRNA, 3' end P
AB209060.1 Homo sapiens mRNA for serine (or cysteine) proteinase inhibitor, clade A, member 3 precursor variant protein P
AY513276.1 Homo sapiens growth-inhibiting protein 25 (GIG25) mRNA, complete cds P
AY513275.1 Homo sapiens growth-inhibiting protein 24 (GIG24) mRNA, complete cds P
BC003559.1 Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, mRNA (cDNA clone MGC:1813 IMAGE:3547133), complete cds PA
BC010530.1 Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, mRNA (cDNA clone MGC:18102 IMAGE:4152174), complete cds PA
BC013189.1 Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, mRNA (cDNA clone IMAGE:3925035), partial cds PA
AK308565.1 Homo sapiens cDNA, FLJ98606
AK093049.1 Homo sapiens cDNA FLJ35730 fis, clone TESTI2003131, highly similar to ALPHA-1-ANTICHYMOTRYPSIN PRECURSOR P
BC034554.1 Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, mRNA (cDNA clone MGC:18107 IMAGE:4152390), complete cds PA

EST sequences (10 of 1753) [Show all sequences]

R14899.1 Clone IMAGE:30005 brain 5' read P
R17936.1 Clone IMAGE:125025 mixed 3' read
AI014485.1 Clone IMAGE:1607280 mammary gland 3' read A
AI016835.1 Clone IMAGE:1639105 testis 3' read A
AI056743.1 Clone IMAGE:1673886 mixed 3' read A
AI081774.1 Clone IMAGE:1661991 mixed 3' read
AI128061.1 Clone IMAGE:1712742 uterus 3' read PA
AI146388.1 Clone IMAGE:1685866 brain 3' read PA
AI151233.1 Clone IMAGE:1715801 placenta 3' read A
AI189564.1 Clone IMAGE:1725015 placenta 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help