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UGID:147672     UniGene Hs.127310     Homo sapiens (human)   UHMK1
U2AF homology motif (UHM) kinase 1 (UHMK1)

Human protein-coding gene UHMK1. Represented by 509 ESTs from 184 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 147672 - Hs.127310]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001118183.1 PREDICTED: serine/threonine-protein kinase Kist isoform 2 M. mulatta 100.0 418
XP_001174268.1 PREDICTED: serine/threonine-protein kinase Kist isoform 1 P. troglodytes 100.0 418
NP_787062.1 UHMK1 gene product H. sapiens 100.0 418
XP_536143.3 PREDICTED: serine/threonine-protein kinase Kist isoform 2 C. lupus familiaris 100.0 418
XP_001491679.2 PREDICTED: serine/threonine-protein kinase Kist isoform 1 E. caballus 100.0 418
NP_001192514.1 serine/threonine-protein kinase Kist B. taurus 100.0 418
XP_002715130.1 PREDICTED: kinase interacting stathmin O. cuniculus 99.8 418
XP_003893037.1 PREDICTED: serine/threonine-protein kinase Kist-like P. anubis 99.7 299
NP_034763.3 Uhmk1 gene product M. musculus 99.5 418
NP_058989.1 Uhmk1 gene product R. norvegicus 99.5 418
NP_001070127.1 uhmk1 gene product D. rerio 80.6 396
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_004002759.1 PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase Kist O. aries 99.3 412
XP_001924285.2 PREDICTED: serine/threonine-protein kinase Kist-like S. scrofa 99.2 258

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; stomach; uterus; liver; thymus; thyroid; mouth; trachea; skin; testis; lung; lymph node; kidney; vascular; connective tissue; placenta; eye; embryonic tissue; mixed; pancreas; mammary gland; adrenal gland; uncharacterized tissue; muscle; prostate; intestine; bone marrow; blood; heart; bladder; cervix; ovary; bone; parathyroid; ascites; spleen; nerve; larynx; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q23.3
UniSTS entry: Chr 1 D2S2902
UniSTS entry: Chr 1 RH98846
UniSTS entry: Chr 2 A006A40
UniSTS entry: Chr 2 G20662
UniSTS entry: Chr 1 RH68936
UniSTS entry: Chr 1 RH64673 [Map Viewer]
UniSTS entry: Chr 1 KIS_3707
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AJ536197.1 Homo sapiens mRNA for KIS protein P
BC043436.2 Homo sapiens cDNA clone IMAGE:5296692 A
NM_175866.4 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), transcript variant 1, mRNA P
AL137257.1 Homo sapiens mRNA; cDNA DKFZp434C1613 (from clone DKFZp434C1613) A
AK026668.1 Homo sapiens cDNA: FLJ23015 fis, clone LNG00818 A
BC001977.1 Homo sapiens, Similar to likely ortholog of yeast ARV1, clone IMAGE:3460560, mRNA A
BC014917.1 Homo sapiens U2AF homology motif (UHM) kinase 1, mRNA (cDNA clone IMAGE:3920939), partial cds PA
AK058195.1 Homo sapiens cDNA FLJ25466 fis, clone TST09304, highly similar to Kinase interacting with leukemia-associated gene (stathmin) P
AK292369.1 Homo sapiens cDNA FLJ75471 complete cds, highly similar to Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA P
BC026046.1 Homo sapiens U2AF homology motif (UHM) kinase 1, mRNA (cDNA clone MGC:39391 IMAGE:4649261), complete cds PA
NM_144624.2 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), transcript variant 3, mRNA P
NM_001184763.1 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), transcript variant 2, mRNA P

EST sequences (10 of 509) [Show all sequences]

AA968478.1 Clone IMAGE:1580207 mixed 3' read
AA947773.1 Clone IMAGE:1584951 lung 3' read
AI096425.1 Clone IMAGE:1685989 brain 3' read A
AI086255.1 Clone IMAGE:1659508 embryonic tissue 3' read A
R23013.1 Clone IMAGE:130954 placenta 5' read
CB044657.1 Clone IMAGE:3218096 intestine 5' read
CB044656.1 Clone IMAGE:3218096 intestine 3' read A
AI146675.1 Clone IMAGE:1697934 uterus 3' read A
CB050847.1 Clone IMAGE:3272181 prostate 3' read A
BX118103.1 Clone IMAGp998B151942_;_IMAGE:787886 embryonic tissue A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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