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UGID:237381     UniGene Hs.442344     Homo sapiens (human)   IRS2
Insulin receptor substrate 2 (IRS2)

Human protein-coding gene IRS2. Represented by 292 ESTs from 149 cDNA libraries. Corresponds to reference sequence NM_003749.2. [UniGene 237381 - Hs.442344]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003740.2 IRS2 gene product H. sapiens 100.0 1337
NP_001074681.1 insulin receptor substrate 2 M. musculus 88.7 1320
XP_700746.4 PREDICTED: insulin receptor substrate 2 D. rerio 54.4 1016
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_002800884.1 PREDICTED: insulin receptor substrate 2-like, partial M. mulatta 98.0 1212
XP_529580.4 PREDICTED: insulin receptor substrate 2, partial P. troglodytes 97.6 1112

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; pancreas; eye; ovary; placenta; kidney; ear; muscle; adrenal gland; ganglia; amniotic fluid; connective tissue; pituitary gland; uterus; mixed; liver; lung; intestine; blood; mammary gland; uncharacterized tissue; testis; lymph node; prostate; stomach; embryonic tissue; salivary gland; spleen; bone; bone marrow; heart; bladder; adipose tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 13
Map position: 13q34
UniSTS entry: Chr 13 SHGC-36212
UniSTS entry: Chr 13 A006G14 [Map Viewer]
UniSTS entry: Chr 13 WI-11813 [Map Viewer]
UniSTS entry: Chr 13 G32344
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC042858.1 Homo sapiens insulin receptor substrate 2, mRNA (cDNA clone IMAGE:5303945) A
NM_003749.2 Homo sapiens insulin receptor substrate 2 (IRS2), mRNA PA
BC063516.1 Homo sapiens cDNA clone IMAGE:4213553, partial cds A
BC066356.1 Homo sapiens cDNA clone IMAGE:5288004 A
AF073310.1 Homo sapiens insulin receptor substrate-2 (IRS2) mRNA, complete cds P
BC110638.1 Homo sapiens cDNA clone IMAGE:6157910 A
BC026044.1 Homo sapiens cDNA clone IMAGE:3928792 A
BC012414.1 Homo sapiens insulin receptor substrate 2, mRNA (cDNA clone IMAGE:3860131), partial cds A
AF161416.1 Homo sapiens HSPC298 mRNA, partial cds A

EST sequences (292)

AA905635.1 Clone IMAGE:1506048 mixed 3' read
AI066632.1 Clone IMAGE:1681836 skin 3' read A
AI089538.1 Clone IMAGE:1686040 brain 3' read A
AI122625.1 Clone IMAGE:1694600 heart 3' read A
R23899.1 Clone IMAGE:131060 placenta 5' read
R23900.1 Clone IMAGE:131060 placenta 3' read A
CB053432.1 Clone IMAGE:3290879 uncharacterized tissue 3' read A
CB053433.1 Clone IMAGE:3290879 uncharacterized tissue 5' read
AI148082.1 Clone IMAGE:1698614 uterus 3' read A
BX106460.1 Clone IMAGp998L211198_;_IMAGE:502436 uterus
AI168652.1 Clone IMAGE:1678047 mixed 3' read A
AI268887.1 Clone IMAGE:1911093 lung 3' read A
CB132629.1 Clone L14ChoiCK0-2-E06 liver 5' read
CB134165.1 Clone L14ChoiCK0-16-D09 liver 5' read A
CB136256.1 Clone L14ChoiCK0-21-C04 liver 5' read
AI299639.1 Clone IMAGE:1896156 lung 3' read A
AI318072.1 Clone IMAGE:1912139 intestine 3' read A
AI359041.1 Clone IMAGE:2012535 brain 3' read A
AI432146.1 Clone IMAGE:2114779 mixed 3' read A
AI458273.1 Clone IMAGE:2145285 mixed 3' read A
AI459239.1 Clone IMAGE:2150702 lung 3' read
R52164.1 Clone IMAGE:154329 mammary gland 3' read
AI492087.1 Clone IMAGE:2108551 uncharacterized tissue 3' read P
AI733263.1 Clone IMAGE:1573170 kidney 3' read P
AI742346.1 Clone IMAGE:2368565 mixed 3' read A
AI745233.1 Clone IMAGE:2364712 mixed 3' read A
R59139.1 Clone IMAGE:41449 brain 5' read
R59140.1 Clone IMAGE:41449 brain 3' read A
AI793287.1 Clone IMAGE:1573170 kidney 5' read P
CB265352.1 adipose tissue 5' read
BX281779.1 Clone IMAGp998F0310146_;_IMAGE:4416002 intestine P
AL044403.1 Clone DKFZp434D072 testis 5' read A
AL044406.1 Clone DKFZp434D092 testis 5' read
AI860710.1 Clone IMAGE:2422972 lung 3' read P
AI862808.1 Clone IMAGE:2410721 lymph node 3' read A
AI919045.1 Clone IMAGE:2257039 stomach 3' read
CB993277.1 Clone IMAGE:30337018 placenta 5' read
AI867402.1 Clone IMAGE:2391431 intestine 3' read P
BX389587.2 Clone CS0DI033YG17 placenta 5' read
BX389588.2 Clone CS0DI033YG17 placenta 5' read
AI971980.1 Clone IMAGE:2531101 ovary 3' read
CD368071.1 Clone UI-H-FT1-bkc-g-11-0-UI lung 3' read PA
AW006549.1 Clone IMAGE:2488687 prostate 3' read A
AW009103.1 Clone IMAGE:2503955 intestine 3' read A
CD558354.1 Clone IMAGE:30396566 brain 5' read
CD678274.1 Clone hp05a10 eye 5' read
CD723366.1 Clone oj21c09 eye 5' read
AW087666.1 Clone IMAGE:2581404 mixed 3' read A
AW134817.1 Clone IMAGE:2712944 mixed 3' read P
AW181956.1 Clone IMAGE:2662460 mixed 3' read A
AW236355.1 Clone IMAGE:2700124 blood 3' read A
CF596551.1 Clone IMAGE:30704629 ovary 5' read
AW294962.1 Clone IMAGE:2727822 uncharacterized tissue 3' read P
AW364197.1 kidney
AW377499.1 intestine
R67459.1 Clone IMAGE:141018 placenta 5' read
AW468527.1 Clone IMAGE:2921406 blood 3' read
AW628910.1 Clone IMAGE:2975198 mixed 3' read A
AW664682.1 Clone IMAGE:2979014 mixed 3' read
AW841902.1 intestine
AW852046.1 intestine
AW900042.1 brain
AW956043.1 uncharacterized tissue
AW961171.1 uncharacterized tissue
CN429563.1 embryonic tissue 5' read
BE042396.1 Clone IMAGE:3037926 intestine 3' read A
AJ706690.1 Clone CMPD00093 heart A
CR736339.1 Clone IMAGp998D24603_;_IMAGE:273767 skin 5' read
CR740380.1 Clone IMAGp998I034682_;_IMAGE:1909706 lung 5' read
H26082.1 Clone IMAGE:162284 mammary gland 5' read
H28086.1 Clone IMAGE:162284 mammary gland 3' read
BE564611.1 Clone IMAGE:3684831 bladder 5' read
CX166209.1 Clone IMAGE:7470083 embryonic tissue 5' read
CX872569.1 Clone IMAGE:7487330 embryonic tissue 5' read
BP392074.1 Clone h-t-263-43 pancreas 3' read A
BE745495.1 Clone IMAGE:3928792 ovary 5' read
BE763866.1 brain
AV686027.1 Clone GKCGYD09 liver 5' read
T19120.1 Clone e01021 testis 5' read
AV688056.1 Clone GKCDMG01 liver 5' read
BE865881.1 Clone IMAGE:3961148 bladder 5' read
BE856074.1 Clone IMAGE:3303953 prostate 3' read A
BE858642.1 Clone IMAGE:3305089 brain 3' read A
BE958381.1 Clone IMAGE:3930065 brain 5' read
BF000135.1 Clone IMAGE:3316324 intestine 3' read P
BF000444.1 Clone IMAGE:3317359 intestine 3' read A
BF032958.1 Clone IMAGE:3859709 ovary 5' read
BF034127.1 Clone IMAGE:3860131 ovary 5' read
BF035983.1 Clone IMAGE:3861590 ovary 5' read
AV739180.1 Clone CBFAZH03 blood 5' read A
BF090435.1 brain
D53276.1 Clone GEN-104D08 brain 3' read A
AV751352.1 Clone NPDBDH02 pituitary gland 5' read
AV751435.1 Clone NPDAGG04 pituitary gland 5' read
AV751587.1 Clone NPDAXC10 pituitary gland 5' read
AV752945.1 Clone NPDBCC08 pituitary gland 5' read
CR986120.1 Clone RZPDp9017P1430 uncharacterized tissue 5' read P
CR988107.1 Clone RZPDp9017N0420 uncharacterized tissue 5' read P
BF110143.1 Clone IMAGE:3566780 lung 3' read
BF131816.1 Clone IMAGE:4052264 kidney 5' read
BY799880.2 Clone HE4939.seq eye 5' read
BF184690.1 Clone IMAGE:4065022 bone marrow 5' read
BF213168.1 Clone IMAGE:4069927 bone marrow 5' read
BF342814.1 Clone IMAGE:4150631 brain 5' read
BF368331.1 placenta
DV460625.1 Clone n4607 ear 5' read
DA174843.1 Clone BRAMY2038048 brain 5' read P
BF695107.1 Clone IMAGE:4247563 muscle 5' read
BF700086.1 Clone IMAGE:4284401 brain 5' read
BF726126.1 Clone by01e03 eye 3' read A
BF726127.1 Clone by01e03 eye 5' read
DA417779.1 Clone BRTHA3027394 brain 5' read
DA410549.1 Clone BRTHA3017358 brain 5' read
BF056606.1 Clone IMAGE:3475911 ovary 3' read P
DA677162.1 Clone NETRP2008377 blood 5' read P
BF526555.1 Clone IMAGE:4213553 brain 5' read
BF576417.1 Clone IMAGE:4288783 muscle 5' read
BF590749.1 Clone IMAGE:3318549 intestine 3' read
BF594231.1 Clone IMAGE:3564226 brain 3' read A
BF793007.1 Clone IMAGE:4346221 adrenal gland 5' read
BF735433.1 amniotic fluid
H83536.1 Clone IMAGE:249315 skin 5' read
BF740269.1 Clone IMAGE:3174306 brain 3' read P
DW427490.1 liver
DW431602.1 liver
DW447830.1 liver
DW450096.1 liver
H96209.1 Clone IMAGE:251346 skin 3' read A
H96746.1 Clone IMAGE:251346 skin 5' read
BF970084.1 Clone IMAGE:4360477 adrenal gland 5' read A
BF971001.1 Clone IMAGE:4358595 adrenal gland 5' read
BF939211.1 Clone IMAGE:3410297 prostate 3' read A
BF940347.1 Clone IMAGE:3433489 ovary 3' read P
BF940792.1 Clone IMAGE:3280801 ganglia 3' read
BF941437.1 Clone IMAGE:3440046 brain 3' read A
N20330.1 Clone IMAGE:264616 skin 3' read A
BG164976.1 Clone IMAGE:4453998 kidney 5' read
DB483509.1 Clone H023097K07 brain 5' read
DB483789.1 Clone H023098L20 brain 5' read
DB548646.1 Clone H023084G23 brain 3' read A
DB552430.1 Clone H023097K07 brain 3' read A
DB552751.1 Clone H023098L20 brain 3' read A
BG253164.1 Clone IMAGE:4472475 liver 5' read
DB479914.1 Clone H023084G23 brain 5' read P
N27604.1 Clone IMAGE:264616 skin 5' read
AL547807.3 Clone CS0DI033YG17 placenta 5' read
N29596.1 Clone IMAGE:270689 skin 3' read A
AL572619.3 Clone CS0DI033YG17 placenta 3' read
N33413.1 Clone IMAGE:273863 skin 3' read A
N35394.1 Clone IMAGE:272089 skin 3' read A
N42921.1 Clone IMAGE:270689 skin 5' read
BG491137.1 Clone IMAGE:4638261 lung 5' read
N44877.1 Clone IMAGE:273767 skin 5' read
BG562924.1 Clone IMAGE:4709538 liver 5' read
N50191.1 Clone IMAGE:281248 brain 5' read
BG618719.1 Clone IMAGE:4766562 liver 5' read
BG184933.1 connective tissue
BG191734.1 connective tissue
BG687405.1 Clone IMAGE:4762574 salivary gland 5' read
BG929289.1 connective tissue
BG897501.1 connective tissue
BG899629.1 connective tissue A
BI037276.1 brain
BG714310.1 Clone IMAGE:4792922 brain 5' read P
BJ994674.1 Clone hmft-0821 liver 5' read A
BJ994675.1 Clone hmft-0821 liver 3' read
BI599121.1 Clone IMAGE:5288600 brain 5' read P
BI600750.1 Clone IMAGE:5288004 brain 5' read
BI554113.1 Clone IMAGE:5309672 brain 5' read
BI554248.1 Clone IMAGE:5309791 brain 5' read
BI769524.1 Clone IMAGE:5208402 mixed 5' read
BI857062.1 Clone IMAGE:5392449 mammary gland 5' read
BI850290.1 Clone IMAGE:4284401 brain 5' read
BI914396.1 Clone IMAGE:5245202 brain 5' read
BI918256.1 Clone IMAGE:5247055 brain 5' read
BM272224.1 pancreas 3' read A
BM272433.1 pancreas 5' read
BM544128.1 Clone IMAGE:5587612 ovary 5' read P
BM553103.1 Clone IMAGE:5742827 brain 5' read P
BM663798.1 Clone UI-E-CL1-afe-c-07-0-UI eye 3' read A
BM671193.1 Clone UI-E-CQ1-agc-e-20-0-UI brain 3' read A
BM671554.1 Clone UI-E-CK1-afj-p-10-0-UI eye 3' read A
BM692576.1 Clone UI-E-CL1-afe-c-07-0-UI eye 5' read
BM700859.1 Clone UI-E-CL1-aek-c-07-0-UI eye 5' read
BM704353.1 Clone UI-E-CK1-afj-p-10-0-UI eye 5' read
BM710040.1 Clone UI-E-CQ1-agc-e-20-0-UI brain 5' read
R29507.1 Clone F1-1021D liver 5' read A
BM801836.1 Clone IMAGE:5581784 eye 5' read
BM805984.1 Clone IMAGE:5731715 brain 5' read
BM888232.1 eye 5' read P
W74105.1 Clone IMAGE:339582 pancreas 5' read
BM969807.1 Clone UI-CF-DU1-abc-l-10-0-UI lung 3' read A
BM983398.1 Clone UI-CF-DU1-aaw-c-20-0-UI lung 3' read A
BQ007494.1 Clone UI-1-BC1-aiw-e-10-0-UI placenta 3' read A
BQ009533.1 Clone IMAGE:5834361 connective tissue 3' read A
BQ014447.1 Clone IMAGE:5833382 connective tissue 3' read A
BQ026675.1 Clone UI-1-BB0-abu-c-08-0-UI placenta 3' read A
BQ214914.1 Clone IMAGE:6049968 skin 5' read
BQ223210.1 Clone IMAGE:6055652 skin 5' read
BQ231877.1 Clone IMAGE:6063134 skin 5' read
BQ270575.1 Clone IMAGE:5780030 pancreas 3' read A
BQ270815.1 Clone IMAGE:5780030 pancreas 5' read
BQ422221.1 Clone IMAGE:6014829 uncharacterized tissue 5' read P
BQ416709.1 Clone IMAGE:5783559 pancreas 3' read A
BQ417015.1 Clone IMAGE:5783559 pancreas 5' read
BQ435294.1 Clone IMAGE:6168343 skin 5' read
BQ440575.1 Clone IMAGE:6157910 skin 5' read
BQ581636.1 Clone IMAGE:6029578 pancreas 3' read
BQ581964.1 Clone IMAGE:6029578 pancreas 5' read
BQ614435.1 Clone IMAGE:6028402 pancreas 5' read
AA031286.1 Clone IMAGE:470383 uterus 3' read A
AA031400.1 Clone IMAGE:470383 uterus 5' read
BQ637098.1 Clone he05f11 eye 5' read A
AA035289.1 Clone IMAGE:471507 uterus 3' read
AA035325.1 Clone IMAGE:471514 uterus 5' read
AA039318.1 Clone IMAGE:485185 uterus 3' read A
AA039419.1 Clone IMAGE:485185 uterus 5' read
BQ711346.1 Clone IMAGE:6278116 spleen 5' read P
AA042821.1 Clone IMAGE:486793 uterus 3' read A
AA042961.1 Clone IMAGE:486793 uterus 5' read
BG056620.1 Clone IMAGE:4169430 brain 3' read
BG060128.1 Clone IMAGE:4147221 brain 3' read P
BG114958.1 Clone IMAGE:4416002 intestine 5' read P
BG119432.1 Clone IMAGE:4444181 liver 5' read
BQ950709.1 Clone IMAGE:6420793 lung 5' read P
BU172202.1 Clone IMAGE:6166894 skin 5' read
BU149738.1 Clone IMAGE:6184684 ganglia 5' read
BQ549162.1 Clone IMAGE:6027741 pancreas 5' read
BQ549644.1 Clone IMAGE:6027741 pancreas 3' read A
BU533051.1 Clone IMAGE:6559148 mixed 5' read A
BU537340.1 Clone IMAGE:6566864 mixed 5' read
BU536016.1 Clone IMAGE:6563847 mixed 5' read
GD136985.1 3' read A
GD158523.1 3' read
T59143.1 Clone IMAGE:74620 spleen 3' read A
T59181.1 Clone IMAGE:74620 spleen 5' read
AA101766.1 Clone IMAGE:490673 uterus 5' read
AA129863.1 Clone IMAGE:490734 uterus 3' read A
T63123.1 Clone IMAGE:79172 lung 5' read
FN164401.1 Clone 274485_1225_1299
FN156570.1 Clone 257034_3010_0489
FN084924.1 Clone 076298_0091_1818
AA134861.1 Clone IMAGE:502436 uterus 5' read
AA134862.1 Clone IMAGE:502436 uterus 3' read A
AA150843.1 Clone IMAGE:505041 uterus 3' read A
AA151015.1 Clone IMAGE:505041 uterus 5' read
BU674146.1 Clone UI-CF-DU0-aaa-n-15-0-UI lung 3' read A
BU740264.1 Clone UI-E-EO0-ahy-n-17-0-UI eye 3' read A
BU782547.1 Clone IMAGE:6123742 pancreas 3' read A
BU782701.1 Clone IMAGE:6123619 pancreas 3' read A
BU783525.1 Clone IMAGE:6123742 pancreas 5' read
BU930574.1 Clone IMAGE:6668631 prostate 5' read
BU931884.1 Clone IMAGE:6672158 ovary 5' read P
BU941471.1 Clone IMAGE:6713679 mixed 5' read
BU945300.1 Clone IMAGE:6735968 mixed 5' read
BU955635.1 Clone IMAGE:6727863 mixed 5' read
HY020382.1 Clone H04D068P13 testis P
HY025388.1 Clone H04D086M07 testis
HY035903.1 Clone H04D124E12 testis P
HY192725.1 Clone H04D029K21 testis
HY209141.1 Clone H04D086M07 testis
CA416129.1 Clone UI-H-FE0-bbs-l-07-0-UI bone 3' read A
CA435900.1 Clone UI-H-DT0-atx-o-23-0-UI connective tissue 3' read A
AA298469.1 prostate 5' read
AA298520.1 prostate 5' read
AA313314.1 intestine 5' read
AA347674.1 heart 3' read
AA350005.1 brain 3' read A
AA369268.1 placenta 5' read
AA375248.1 lung 5' read
CA952668.1 Clone IMAGE:6226262 pancreas 5' read
AA481289.1 Clone IMAGE:746311 lymph node 5' read
AA483359.1 Clone IMAGE:909963 bone A
AA483480.1 Clone IMAGE:910038 bone
AA512855.1 Clone IMAGE:911082 bone A
AA505676.1 Clone IMAGE:966136 mammary gland 3' read
AA553757.1 Clone IMAGE:1014951 intestine 3' read A
AA557837.1 Clone IMAGE:1045371 prostate
AA617908.1 Clone IMAGE:1143036 lung 3' read
AA642627.1 Clone IMAGE:1157820 prostate 3' read
AA707485.1 Clone 1291991 testis 3' read A
AA732771.1 Clone 1344134 testis 3' read
AA718930.1 Clone 1292462 testis 3' read A
AA782271.1 Clone IMAGE:855206 lung 3' read
AA828943.1 Clone IMAGE:1374346 ovary A
AA829040.1 Clone IMAGE:1374418 ovary A
AA829083.1 Clone IMAGE:1374466 ovary A
AA829188.1 Clone IMAGE:1374394 ovary A
AA829569.1 Clone IMAGE:1384303 ovary A
AA872787.1 Clone IMAGE:1472877 kidney 3' read A
AA876661.1 Clone IMAGE:1290814 bone A
AA953212.1 Clone IMAGE:1573170 kidney 3' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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