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UGID:169052     UniGene Hs.248141     Homo sapiens (human)   KCNJ11
Potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11)

Human protein-coding gene KCNJ11. Represented by 32 ESTs from 22 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 169052 - Hs.248141]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000516.3 KCNJ11 gene product H. sapiens 100.0 389
XP_521849.2 PREDICTED: ATP-sensitive inward rectifier potassium channel 11 isoform 2 P. troglodytes 99.7 389
NP_034732.1 Kcnj11 gene product M. musculus 97.7 389
NP_001034916.1 kcnj11 gene product D. rerio 81.1 350
NP_001185812.1 potassium inwardly-rectifying channel, subfamily J, member 8 X. laevis 77.2 377
NP_732871.1 inwardly rectifying potassium channel 2, isoform B D. melanogaster 49.0 353
NP_001256976.1 Protein IRK-2, isoform b C. elegans 45.8 271
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001089155.1 PREDICTED: ATP-sensitive inward rectifier potassium channel 11 M. mulatta 99.5 389
XP_003910215.1 PREDICTED: ATP-sensitive inward rectifier potassium channel 11 isoform 1 P. anubis 99.5 389

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; muscle; intestine; pancreas; thyroid; brain; kidney; mammary gland; mixed; prostate; liver; ovary; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.1
UniSTS entry: Chr 11 RH41979
UniSTS entry: Chr 11 KCNJ11_V176
UniSTS entry: Chr 11 RH80766
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 1 L18426
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC064497.1 Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 11, mRNA (cDNA clone MGC:71115 IMAGE:6279724), complete cds PA
BC112358.1 Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 11, mRNA (cDNA clone MGC:133230 IMAGE:40032947), complete cds P
NM_000525.3 Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11), transcript variant 1, mRNA P
AK314943.1 Homo sapiens cDNA, FLJ95855, highly similar to Homo sapiens potassium inwardly-rectifying channel, subfamily J,member 11 (KCNJ11), mRNA P
AK301550.1 Homo sapiens cDNA FLJ51349 complete cds, highly similar to ATP-sensitive inward rectifier potassium channel 11 P
NM_001166290.1 Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11), transcript variant 2, mRNA P
BC040617.1 Homo sapiens, Similar to potassium inwardly-rectifying channel, subfamily J, member 11, clone IMAGE:5723755, mRNA, partial cds PA

EST sequences (32)

CB112941.1 Clone L6ChoCK0-10-D05 liver 5' read P
AI309080.1 Clone IMAGE:2058463 mammary gland 3' read A
AI313045.1 Clone IMAGE:2050551 mammary gland 3' read A
AI377272.1 Clone IMAGE:2091533 mixed 3' read
AI792302.1 Clone IMAGE:1156538 kidney 5' read P
BX281091.1 Clone IMAGp998H1812322_;_IMAGE:5574209 intestine P
BE019467.1 Clone IMAGE:3010656 muscle 5' read
BE159475.1 thyroid P
BE253084.1 Clone IMAGE:3357479 eye 5' read P
BP245852.1 Clone HKR04330 kidney 5' read P
BE294700.1 Clone IMAGE:3529373 muscle 5' read
BP396905.1 Clone hbt12204 pancreas 3' read A
DN993190.1 Clone TC123976 brain 5' read
DA074949.1 Clone BRACE2026608 brain 5' read P
DA533187.1 Clone FEBRA2027049 brain 5' read P
DA495241.1 Clone FCBBF3007773 brain 5' read P
BF842095.1 thyroid P
EC526008.1 prostate
EC529621.1 prostate
BG394461.1 Clone IMAGE:4579460 eye 5' read P
DC392804.1 Clone TBAES2001752 mammary gland 5' read P
DC305775.1 Clone BRACE2041639 brain 5' read
BM480315.1 Clone IMAGE:5574209 intestine 5' read P
BM546966.1 Clone IMAGE:5723755 ovary 5' read P
BM676395.1 Clone UI-E-EJ0-ahp-i-19-0-UI eye 3' read A
BM713280.1 Clone UI-E-EJ0-ahp-i-19-0-UI eye 5' read
BQ917358.1 Clone IMAGE:6200055 nerve 5' read P
BU738791.1 Clone UI-E-EJ0-ahp-i-19-0-UI eye 3' read A
CA777857.1 Clone IMAGE:6217342 pancreas 3' read A
CA778121.1 Clone IMAGE:6217342 pancreas 5' read
F21303.1 Clone 049-X4-20 muscle
AA679741.1 Clone IMAGE:1156538 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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