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UGID:161544     UniGene Hs.196384     Homo sapiens (human)   PTGS2
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2)

Human protein-coding gene PTGS2. Represented by 165 ESTs from 80 cDNA libraries. Corresponds to reference sequence NM_000963.2. [UniGene 161544 - Hs.196384]

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; vascular; prostate; placenta; uterus; uncharacterized tissue; pharynx; brain; lung; cervix; mixed; kidney; pancreas; stomach; mammary gland; skin; connective tissue; bone; embryonic tissue; eye; spleen; esophagus; trachea; larynx; muscle; bone marrow; nerve; intestine; liver; thyroid; umbilical cord
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q25.2-q25.3
UniSTS entry: Chr 1 SHGC-76038 [Map Viewer]
UniSTS entry: Chr 1 G65470
UniSTS entry: Chr 1 GDB:455285
UniSTS entry: Chr 1 PTGS2-235F
UniSTS entry: Chr 1 G65466
UniSTS entry: Chr 1 G65467
UniSTS entry: Chr 1 G65468
UniSTS entry: Chr 1 G65469
UniSTS entry: Chr 1 G65465
UniSTS entry: Chr 1 G63790
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000963.2 Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), mRNA PA
AY462100.1 Homo sapiens cyclooxygenase 2 (COX2) mRNA, complete cds P
AJ634912.1 Homo sapiens mRNA for putative cyclooxygenase-2 (COX-2 gene), splice variant COX-2a P
M90100.1 Homo sapiens cyclooxygenase-2 (Cox-2) mRNA, complete cds PA
BC013734.1 Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), mRNA (cDNA clone MGC:9576 IMAGE:3880850), complete cds PA
AK292167.1 Homo sapiens cDNA FLJ75306 complete cds, highly similar to Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), mRNA P
HM473188.1 Homo sapiens prostaglandin-endoperoxidase synthase 2 (PTGS2) mRNA, partial cds
AY151286.1 Homo sapiens cyclooxygenase 2b mRNA, complete cds; alternatively spliced PA
L15326.1 Human endoperoxide synthase type II mRNA, complete cds P

EST sequences (165)

AI022012.1 Clone IMAGE:1651583 skin 3' read P
AI123006.1 Clone IMAGE:1509904 mixed 3' read A
BX115842.1 Clone IMAGp998E03223_;_IMAGE:147050 placenta A
CB146285.1 Clone L16HLK3-20-H12 liver 5' read P
CB143773.1 Clone L16HLK3-17-H10 liver 5' read P
AI401793.1 Clone IMAGE:2119661 prostate 3' read
AI610346.1 Clone IMAGE:2188171 stomach 3' read
AI610431.1 Clone IMAGE:2188151 stomach 3' read A
AI669722.1 Clone IMAGE:2314993 prostate 3' read A
CB243167.1 Clone UI-CF-FN0-agc-c-16-0-UI lung 3' read A
AI783660.1 Clone IMAGE:2252336 prostate 3' read
AI826642.1 Clone IMAGE:2417413 prostate 3' read
AI935944.1 Clone IMAGE:2460200 prostate 3' read
CB960307.1 Clone IMAGE:30343238 placenta 5' read P
CD104624.1 Clone IMAGE:30369464 mixed 5' read
BX363285.2 Clone CS0DK011YO09 cervix 5' read P
BX374215.2 Clone CS0DK011YO09 cervix 3' read A
BX370552.1 Clone CS0DK011YO09 cervix 5' read P
AI950710.1 Clone IMAGE:2547435 lung 3' read A
AI970555.1 Clone IMAGE:2481292 lung 3' read A
AI971172.1 Clone IMAGE:2488782 prostate 3' read A
CD365731.1 Clone UI-H-FT2-bjk-f-03-0-UI lung 3' read A
CD520958.1 Clone IMAGE:30412987 blood 5' read A
AW051749.1 Clone IMAGE:2545024 kidney 3' read
AW073894.1 Clone IMAGE:2575329 mixed 3' read A
AW150290.1 Clone IMAGE:2629750 uterus 3' read A
AW059881.1 blood
AW276095.1 Clone IMAGE:2753598 lung 3' read A
AW467769.1 Clone IMAGE:2919898 blood 3' read A
CD609928.1 uncharacterized tissue P
CD609929.1 uncharacterized tissue P
CD609930.1 uncharacterized tissue P
CD609931.1 uncharacterized tissue P
AW629747.1 Clone IMAGE:2968129 mixed 5' read
AW818573.1 stomach P
CK823042.1 Clone IMAGE:6135592 pancreas 3' read A
CK823043.1 Clone IMAGE:6135592 pancreas 5' read
R80217.1 Clone IMAGE:147050 placenta 3' read A
R80322.1 Clone IMAGE:147050 placenta 5' read
AW955541.1 uncharacterized tissue
CN337322.1 embryonic tissue 5' read P
CN337323.1 embryonic tissue 5' read P
AJ705220.1 Clone BLPD00142 bone marrow
CV023684.1 mixed 5' read P
BP204393.1 Clone CAS02181 vascular 5' read
BP205024.1 Clone CAS03928 vascular 5' read
BP205156.1 Clone CAS04419 vascular 5' read
BP205519.1 Clone CAS05175 vascular 5' read P
BP205563.1 Clone CAS05317 vascular 5' read
BP206145.1 Clone CAS07353 vascular 5' read
BP206185.1 Clone CAS07468 vascular 5' read
BP207345.1 Clone CAS10766 vascular 5' read
BP207892.1 Clone CAS12222 vascular 5' read
BP202958.1 Clone CAE01173 vascular 5' read P
BP335244.1 Clone SMR00473 vascular 5' read P
BP335415.1 Clone SMR01266 vascular 5' read P
BP335898.1 Clone SMR04184 vascular 5' read P
BP336843.1 Clone SMR06744 vascular 5' read P
BP337788.1 Clone SMR09283 vascular 5' read P
BP337860.1 Clone SMR09475 vascular 5' read P
BE673090.1 Clone IMAGE:3248637 prostate 3' read P
BE717711.1 pharynx P
BE785396.1 Clone IMAGE:3880850 lung 5' read P
DN995052.1 Clone TC119565 brain 5' read P
D58162.1 Clone GEN-352C12 vascular 5' read
D58371.1 Clone GEN-367G10 vascular 5' read
D61723.1 Clone GEN-203D05 vascular 5' read
BE937429.1 stomach P
AV756509.1 Clone BMFAUA12 bone marrow 5' read
T29235.1 bone 5' read P
BF211384.1 Clone IMAGE:4047008 bone marrow 5' read A
BF326657.1 mammary gland
BF351506.1 thyroid
DA170263.1 Clone BRAMY2032263 brain 5' read P
DA277667.1 Clone BRCOC2005004 brain 5' read P
BF687530.1 Clone IMAGE:4065728 brain 5' read
DA182079.1 Clone BRAMY2047223 brain 5' read P
DA543033.1 Clone HCASM2000349 vascular 5' read
DA670448.1 Clone NETRP2000534 blood 5' read
DA670627.1 Clone NETRP2000741 blood 5' read P
DA670802.1 Clone NETRP2000939 blood 5' read P
DA670870.1 Clone NETRP2001017 blood 5' read
DA671474.1 Clone NETRP2001742 blood 5' read
DA671756.1 Clone NETRP2002087 blood 5' read P
DA671987.1 Clone NETRP2002369 blood 5' read
DA672536.1 Clone NETRP2003008 blood 5' read
DA672543.1 Clone NETRP2003016 blood 5' read
DA672566.1 Clone NETRP2003040 blood 5' read P
DA672971.1 Clone NETRP2003506 blood 5' read P
DA549596.1 Clone HCASM2008141 vascular 5' read P
DA673400.1 Clone NETRP2003995 blood 5' read P
DA673460.1 Clone NETRP2004062 blood 5' read P
DA673694.1 Clone NETRP2004337 blood 5' read
DA673907.1 Clone NETRP2004588 blood 5' read
DA673991.1 Clone NETRP2004683 blood 5' read
DA674388.1 Clone NETRP2005141 blood 5' read
DA674666.1 Clone NETRP2005465 blood 5' read P
DA373879.1 Clone BRTHA2004646 brain 5' read
DA674771.1 Clone NETRP2005591 blood 5' read P
DA675888.1 Clone NETRP2006887 blood 5' read P
DA675940.1 Clone NETRP2006945 blood 5' read
DA675968.1 Clone NETRP2006980 blood 5' read P
AW613332.1 Clone IMAGE:2968129 mixed 3' read A
BE439627.1 eye A
DA486815.1 Clone FCBBF2004469 brain 5' read P
DA381783.1 Clone BRTHA2015474 brain 5' read
DA676086.1 Clone NETRP2007115 blood 5' read
DA676702.1 Clone NETRP2007825 blood 5' read P
DA676889.1 Clone NETRP2008047 blood 5' read P
DA677048.1 Clone NETRP2008241 blood 5' read P
DA678032.1 Clone NETRP2009369 blood 5' read P
DA882455.1 Clone PUAEN2001997 vascular 5' read P
DA994617.1 Clone SYNOV4007483 connective tissue 5' read P
DA956826.1 Clone SPLEN2035919 spleen 5' read
DA887945.1 Clone PUAEN2008563 vascular 5' read
DB019295.1 Clone TESOP2009329 esophagus 5' read P
BF753230.1 mammary gland
DB223983.1 Clone TRACH3015459 trachea 5' read P
BF825245.1 larynx
BF939218.1 Clone IMAGE:3410349 prostate 3' read A
BG152882.1 Clone IMAGE:3433101 prostate 3' read A
BG055155.1 Clone IMAGE:3432296 prostate 3' read P
DB548794.1 Clone H023084P10 brain 3' read A
DB480063.1 Clone H023084P10 brain 5' read P
AL583668.3 Clone CS0DK012YH07 cervix 5' read P
BG236304.1 Clone IMAGE:4142036 blood 3' read A
BI048877.1 uterus
BI335813.1 skin
BM126546.1 Clone IMAGE:5675667 pancreas 5' read
BM128780.1 Clone IMAGE:5676706 pancreas 3' read P
BM129013.1 Clone IMAGE:5676706 pancreas 5' read P
ES315871.1 skin
BM978796.1 Clone UI-CF-DU1-adp-e-23-0-UI lung 3' read A
AL691944.1 Clone DKFZp313C2036 uncharacterized tissue 5' read
AL691954.1 Clone DKFZp313D2036 uncharacterized tissue 5' read
AL710680.1 Clone DKFZp686E1972 muscle 5' read P
AL710813.1 Clone DKFZp686J1373 muscle 5' read P
AL710848.1 Clone DKFZp686N0473 muscle 5' read P
AL712736.1 Clone DKFZp686K1290 muscle 5' read P
BM988211.1 Clone IMAGE:5861835 uncharacterized tissue 3' read A
BQ002136.1 Clone IMAGE:5843740 connective tissue 3' read A
BQ005329.1 Clone IMAGE:5848531 connective tissue 3' read A
BQ025834.1 Clone UI-1-BB1p-aye-h-07-0-UI placenta 3' read A
BQ100700.1 Clone IMAGE:6135592 pancreas 3' read A
BQ100978.1 Clone IMAGE:6135592 pancreas 5' read
BQ574350.1 Clone UI-H-EZ1-baz-d-02-0-UI bone 3' read A
BQ722004.1 Clone IMAGE:6190589 nerve 5' read P
BU493602.1 intestine
C02258.1 uncharacterized tissue
FN076139.1 Clone 053608_1785_1693
FN095178.1 Clone 104896_1456_2975
CA308732.1 Clone UI-H-FT1-bia-j-17-0-UI lung 3' read PA
CA309056.1 Clone UI-H-FT1-bie-i-15-0-UI lung 3' read A
CA436148.1 Clone UI-H-DT0-atz-m-16-0-UI connective tissue 3' read A
CA445948.1 Clone UI-H-EI0-axa-n-21-0-UI connective tissue 3' read A
AA296431.1 umbilical cord 5' read P
AA298098.1 bone 5' read
AA371396.1 prostate 5' read
AA565385.1 Clone IMAGE:1013775 intestine 3' read
AA593850.1 Clone IMAGE:1084346 intestine 3' read A
AA644211.1 Clone IMAGE:845477 lung 3' read A
AA649944.1 Clone IMAGE:1187505 prostate 3' read
AA661753.1 Clone IMAGE:1219223 prostate 3' read A
AA825346.1 Clone IMAGE:1416299 lung 3' read
AA918509.1 Clone IMAGE:1535641 kidney 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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