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UGID:142456     UniGene Hs.98712     Homo sapiens (human)   TXNDC2
Thioredoxin domain containing 2 (spermatozoa) (TXNDC2)

Human protein-coding gene TXNDC2. Represented by 92 ESTs from 9 cDNA libraries. EST representation biased toward testis; normal; adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 142456 - Hs.98712]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001091999.1 TXNDC2 gene product H. sapiens 100.0 552
NP_705739.2 Txndc2 gene product M. musculus 48.6 532
Other hits (2 of 8) [Show all]SpeciesId(%)Len(aa)
XP_001135716.1 PREDICTED: thioredoxin domain-containing protein 2 isoform 2 P. troglodytes 93.3 491
XP_003914199.1 PREDICTED: thioredoxin domain-containing protein 2 isoform 1 P. anubis 86.8 417

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: testis [show more like this]
normal [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; placenta
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
UniSTS entry: RH92269
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC050132.1 Homo sapiens thioredoxin domain containing 2 (spermatozoa), mRNA (cDNA clone MGC:35026 IMAGE:5164861), complete cds PA
NM_032243.5 Homo sapiens thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 1, mRNA PA
EF560747.1 Homo sapiens clone IMAGp998K0211411 TXNDC2 protein (TXNDC2) mRNA, complete cds PA
NM_001098529.1 Homo sapiens thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 2, mRNA PA
AF080095.1 Homo sapiens sperm-specific thioredoxin (Sptrx) mRNA, complete cds P
AK097656.1 Homo sapiens cDNA FLJ40337 fis, clone TESTI2032044, moderately similar to THIOREDOXIN P
AK303045.1 Homo sapiens cDNA FLJ61503 complete cds, moderately similar to Thioredoxin domain-containing protein 2 P

EST sequences (10 of 92) [Show all sequences]

AI125222.1 Clone IMAGE:1736490 testis 3' read PA
BX281456.1 Clone IMAGp998G194412_;_IMAGE:1736490 testis P
CD557557.1 Clone IMAGE:30390325 testis 5' read P
DB040404.1 Clone TESTI2027208 testis 5' read P
DB040434.1 Clone TESTI2027248 testis 5' read P
DB028036.1 Clone TESTI2010775 testis 5' read P
DB028163.1 Clone TESTI2010960 testis 5' read P
DB028603.1 Clone TESTI2011541 testis 5' read P
DB041524.1 Clone TESTI2028621 testis 5' read P
DB041750.1 Clone TESTI2028907 testis 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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