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UGID:142035     UniGene Hs.97542     Homo sapiens (human)   PLCZ1
Phospholipase C, zeta 1 (PLCZ1)

Human protein-coding gene PLCZ1. Represented by 58 ESTs from 11 cDNA libraries. EST representation biased toward testis. Corresponds to 2 reference sequences (different isoforms). [UniGene 142035 - Hs.97542]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_149114.2 PLCZ1 gene product H. sapiens 100.0 607
XP_001160159.1 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform 3 P. troglodytes 99.7 607
NP_473407.2 Plcz1 gene product M. musculus 77.7 641
NP_001090146.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 X. laevis 50.6 605
XP_694028.3 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4, partial D. rerio 50.3 485
NP_741067.1 Protein PLL-1, isoform b C. elegans 49.5 194
XP_960744.2 hypothetical protein NCU01266 N. crassa 46.4 166
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
XP_001095846.2 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 isoform 1 M. mulatta 96.4 607
XP_003906128.1 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 P. anubis 96.4 607

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: testis [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; uncharacterized tissue; mixed; brain
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12.3
UniSTS entry: Chr 12 AB070109
UniSTS entry: Chr 12 RH92603
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC125067.1 Homo sapiens phospholipase C, zeta 1, mRNA (cDNA clone MGC:149685 IMAGE:40117397), complete cds P
AY035866.1 Homo sapiens testis-development related NYD-SP27 mRNA, complete cds PA
NM_033123.3 Homo sapiens phospholipase C, zeta 1 (PLCZ1), transcript variant 1, mRNA PA
AK292279.1 Homo sapiens cDNA FLJ78623 complete cds, highly similar to Homo sapiens phospholipase C, zeta 1 (PLCZ1), mRNA PA
AK314516.1 Homo sapiens cDNA, FLJ95335 P
AK097555.1 Homo sapiens cDNA FLJ40236 fis, clone TESTI2023214, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC P
NR_073075.1 Homo sapiens phospholipase C, zeta 1 (PLCZ1), transcript variant 2, non-coding RNA PA
AF532185.1 Homo sapiens PLC-zeta (PLCZ1) mRNA, complete cds P

EST sequences (10 of 58) [Show all sequences]

AA993718.1 Clone IMAGE:1619981 testis 3' read A
BX110570.1 Clone IMAGp998O141787_;_IMAGE:728677 testis P
AI217888.1 Clone IMAGE:1755869 testis 3' read
AF012362.1 Clone TDP3.12b testis
AA824315.1 Clone 1391812 testis 3' read A
AI935040.1 Clone IMAGE:2328433 mixed 3' read PA
CD634752.1 uncharacterized tissue P
CD634753.1 uncharacterized tissue P
CD634754.1 uncharacterized tissue P
CD634755.1 uncharacterized tissue

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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