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UGID:130865     UniGene Hs.861     Homo sapiens (human)   MAPK3
Mitogen-activated protein kinase 3 (MAPK3)

Human protein-coding gene MAPK3. Represented by 524 ESTs from 238 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 130865 - Hs.861]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003916792.1 PREDICTED: mitogen-activated protein kinase 3 isoform 1 P. anubis 100.0 378
NP_002737.2 MAPK3 gene product H. sapiens 100.0 378
NP_036082.1 Mapk3 gene product M. musculus 99.7 377
NP_059043.1 Mapk3 gene product R. norvegicus 99.7 377
XP_001915560.1 PREDICTED: mitogen-activated protein kinase 3 E. caballus 99.7 365
NP_958915.1 mapk3 gene product D. rerio 94.9 390
NP_001083548.1 mitogen-activated protein kinase 1 X. laevis 93.3 360
NP_001104349.1 rolled, isoform E D. melanogaster 91.2 375
NP_001022583.1 Protein MPK-1, isoform a C. elegans 86.5 340
XP_959713.2 mitogen-activated kinase-2 N. crassa 65.7 340
NP_192046.1 mitogen-activated protein kinase 4 A. thaliana 58.8 371
NP_009537.1 Fus3p S. cerevisiae 58.6 350
XP_001690850.1 mitogen-activated protein kinase 6 C. reinhardtii 58.3 367
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_510921.3 PREDICTED: mitogen-activated protein kinase 3 P. troglodytes 99.5 378
NP_001238964.1 mitogen-activated protein kinase 3 C. lupus familiaris 99.2 377

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; uncharacterized tissue; mixed; lung; intestine; placenta; uterus; ovary; lymph; skin; pancreas; embryonic tissue; kidney; testis; bone; mammary gland; nerve; larynx; epididymis; blood; stomach; prostate; muscle; cervix; connective tissue; ascites; heart; adrenal gland; liver; ganglia; vascular; thyroid; amniotic fluid; bladder; mouth; adipose tissue; lymph node; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 16 RH77963
UniSTS entry: Chr 16 SHGC-61070
UniSTS entry: Chr 16 G15873
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

M84490.1 Human extracellular signal-regulated kinase 1 mRNA, 3' end PA
BX537897.1 Homo sapiens mRNA; cDNA DKFZp686O0215 (from clone DKFZp686O0215) PA
NM_002746.2 Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1, mRNA PA
NM_001040056.1 Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 2, mRNA PA
BC000205.1 Homo sapiens mitogen-activated protein kinase 3, mRNA (cDNA clone IMAGE:3350666), partial cds PA
Z11696.1 H.sapiens 44kDa protein kinase related to rat ERK1 P
BC013992.1 Homo sapiens mitogen-activated protein kinase 3, mRNA (cDNA clone MGC:20180 IMAGE:3634492), complete cds PA
DQ399291.1 Homo sapiens extracellular signal-regulated kinase-1 splice variant mRNA, complete cds, alternatively spliced P
NM_001109891.1 Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 3, mRNA PA
AK307995.1 Homo sapiens cDNA, FLJ97943 P
AY033608.1 Homo sapiens extracellular signal-related kinase 1c mRNA, complete cds P
AY033607.1 Homo sapiens extracellular signal-related kinase 1b mRNA, complete cds P
AK091009.1 Homo sapiens cDNA FLJ33690 fis, clone BRAWH2002967, highly similar to Mitogen-activated protein kinase 3 (EC 2.7.11.24) P
X60188.1 Human ERK1 mRNA for protein serine/threonine kinase PA

EST sequences (10 of 524) [Show all sequences]

AA954390.1 Clone IMAGE:1564918 mixed 3' read
AA988225.1 Clone IMAGE:1604686 lung 3' read
AA904487.1 Clone IMAGE:1507220 mixed 3' read
AA921996.1 Clone IMAGE:1543576 mixed 3' read
AA948434.1 Clone IMAGE:1560329 intestine 3' read
AI092217.1 Clone IMAGE:1691150 heart 3' read
AI124000.1 Clone IMAGE:1694908 uterus 3' read
BX108707.1 Clone IMAGp998C05280_;_IMAGE:49161 brain A
AI185928.1 Clone IMAGE:1742418 lung 3' read
AI192103.1 Clone IMAGE:1685961 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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