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UGID:130858     UniGene Hs.846     Homo sapiens (human)   CXCR2
Chemokine (C-X-C motif) receptor 2 (CXCR2)

Human protein-coding gene CXCR2. Represented by 184 ESTs from 28 cDNA libraries. EST representation biased toward blood; adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 130858 - Hs.846]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001096131.1 C-X-C chemokine receptor type 2 P. troglodytes 100.0 359
NP_001161770.1 CXCR2 gene product H. sapiens 100.0 359
NP_034039.1 Cxcr2 gene product M. musculus 74.7 358
NP_001082234.1 chemokine (C-X-C motif) receptor 1 X. laevis 63.2 350
XP_001337093.2 PREDICTED: c-X-C chemokine receptor type 1-like D. rerio 47.5 324
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003907985.1 PREDICTED: c-X-C chemokine receptor type 2 isoform 1 P. anubis 92.4 354
XP_001088762.2 PREDICTED: c-X-C chemokine receptor type 2, partial M. mulatta 91.9 368

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blood [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; mixed; heart; spleen; brain; adrenal gland; uncharacterized tissue; placenta; lung; pharynx; thymus; prostate; trachea; connective tissue; bone; intestine
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 SHGC-35278 [Map Viewer]
UniSTS entry: Chr 2 RH69171
UniSTS entry: Chr 2 STS-L19593
UniSTS entry: Chr 2 PMC135988P2
UniSTS entry: Chr 2 PMC155779P3
UniSTS entry: Chr 2 PMC310709P2
UniSTS entry: Chr 2 IL8R-1
UniSTS entry: Chr 2 PMC155779P1
UniSTS entry: Chr 2 PMC155779P2
UniSTS entry: Chr 2 RH78907
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M94582.1 Human interleuken 8 receptor B mRNA, complete cds P
NM_001557.3 Homo sapiens chemokine (C-X-C motif) receptor 2 (CXCR2), transcript variant 1, mRNA PA
L19593.1 Homo sapiens interleukin 8 receptor beta (IL8RB) mRNA, complete cds P
M73969.1 Human interleukin-8 receptor type B (IL8RB) mRNA, complete cds PA
AK290906.1 Homo sapiens cDNA FLJ78215 complete cds, highly similar to Homo sapiens interleukin 8 receptor beta (IL8RB) mRNA P
AK312664.1 Homo sapiens cDNA, FLJ93056, Homo sapiens interleukin 8 receptor, beta (IL8RB), mRNA P
U11878.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB10, partial cds
U11877.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB9, partial cds
U11876.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB7, partial cds
U11875.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB4, partial cds
U11874.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB3, partial cds
U11873.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB2, partial cds
U11872.1 Human interleukin-8 receptor type B (IL8RB) mRNA, splice variant IL8RB1, partial cds
NM_001168298.1 Homo sapiens chemokine (C-X-C motif) receptor 2 (CXCR2), transcript variant 2, mRNA PA
BC037961.1 Homo sapiens interleukin 8 receptor, beta, mRNA (cDNA clone MGC:46215 IMAGE:5752441), complete cds PA

EST sequences (10 of 184) [Show all sequences]

CB321789.1 Clone UI-CF-EN1-aej-f-18-0-UI lung 3' read PA
AW028346.1 Clone IMAGE:2536574 thymus 3' read
CD695992.1 pharynx P
CD612009.1 uncharacterized tissue
CD612010.1 uncharacterized tissue P
AW969370.1 uncharacterized tissue
CN832049.1 Clone IMAGE:7001966 mixed 5' read P
CN836893.1 Clone IMAGE:7001968 mixed 5' read P
CN837002.1 Clone IMAGE:7001967 mixed 5' read P
CN837164.1 Clone IMAGE:7001968 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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