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UGID:140633     UniGene Hs.82327     Homo sapiens (human)   GSS
Glutathione synthetase (GSS)

Human protein-coding gene GSS. Represented by 855 ESTs from 323 cDNA libraries. Corresponds to reference sequence NM_000178.2. [UniGene 140633 - Hs.82327]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003953759.1 PREDICTED: glutathione synthetase P. troglodytes 100.0 473
NP_000169.1 GSS gene product H. sapiens 100.0 473
NP_032206.1 glutathione synthetase M. musculus 92.4 473
NP_001081013.1 glutathione synthetase X. laevis 70.9 473
NP_001006104.1 gss gene product D. rerio 68.0 474
XP_001691543.1 glutathione synthetase C. reinhardtii 52.4 251
NP_568495.2 glutathione synthetase A. thaliana 49.3 297
NP_788926.2 glutathione synthetase, isoform H D. melanogaster 48.7 339
NP_496011.1 Protein GSS-1 C. elegans 46.1 221
NP_014593.1 glutathione synthase S. cerevisiae 45.4 269
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
XP_003904866.1 PREDICTED: glutathione synthetase isoform 1 P. anubis 99.4 473
XP_001101751.1 PREDICTED: glutathione synthetase M. mulatta 98.7 473

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; lung; mouth; uterus; testis; mixed; pancreas; liver; prostate; skin; uncharacterized tissue; eye; bone marrow; placenta; kidney; bone; ascites; mammary gland; muscle; vascular; cervix; heart; embryonic tissue; connective tissue; epididymis; blood; ovary; thymus; stomach; spleen; umbilical cord; esophagus; adrenal gland; thyroid; lymph; bladder; pituitary gland; adipose tissue; nerve; pineal gland; parathyroid; salivary gland; lymph node
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q11.2
UniSTS entry: Chr 20 A006I18
UniSTS entry: Chr 20 MARC_11817-11818:1029268323:1
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000178.2 Homo sapiens glutathione synthetase (GSS), mRNA PA
BC007927.1 Homo sapiens glutathione synthetase, mRNA (cDNA clone MGC:14098 IMAGE:3946317), complete cds PA
U34683.1 Human glutathione synthetase mRNA, complete cds P
AK311567.1 Homo sapiens cDNA, FLJ18609 P
AK311421.1 Homo sapiens cDNA, FLJ18463 P
AK312492.1 Homo sapiens cDNA, FLJ92853, highly similar to Homo sapiens glutathione synthetase (GSS), mRNA P
AB459500.1 Homo sapiens GSS mRNA for glutathione synthetase, complete cds P
AK298292.1 Homo sapiens cDNA FLJ50601 complete cds, highly similar to Glutathione synthetase (EC P
AK293144.1 Homo sapiens cDNA FLJ51785 complete cds, highly similar to Glutathione synthetase (EC P

EST sequences (10 of 855) [Show all sequences]

AA910685.1 Clone IMAGE:1520656 kidney 3' read A
AI034479.1 Clone IMAGE:1656574 mixed 3' read A
AA946754.1 Clone IMAGE:1589757 kidney 3' read A
AI074150.1 Clone IMAGE:1637182 kidney 3' read A
AI140890.1 Clone IMAGE:1690706 mixed 3' read A
BX117867.1 Clone IMAGp998A01144_;_IMAGE:28239 brain A
AI193653.1 Clone IMAGE:1744478 lung 3' read A
AI268683.1 Clone IMAGE:1911675 lung 3' read A
CB106782.1 Clone L3SNU475-10-G03 liver 5' read P
CB107033.1 Clone L3SNU475-12-C08 liver 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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