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UGID:132230     UniGene Hs.7946     Homo sapiens (human)   MTUS1
Microtubule associated tumor suppressor 1 (MTUS1)

Human protein-coding gene MTUS1. Represented by 704 ESTs from 250 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 132230 - Hs.7946]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001001924.1 MTUS1 gene product H. sapiens 100.0 1269
XP_003311667.1 PREDICTED: microtubule-associated tumor suppressor 1-like isoform 1 P. troglodytes 99.6 516
NP_001005863.1 Mtus1 gene product M. musculus 76.9 1209
NP_001082742.1 microtubule-associated tumor suppressor 1 homolog X. laevis 64.9 566
NP_001071076.1 mtus1a gene product D. rerio 60.5 439
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_003902517.1 PREDICTED: microtubule-associated tumor suppressor 1 homolog isoform 1 P. anubis 96.0 1270
XP_002805318.1 PREDICTED: microtubule-associated tumor suppressor 1 homolog M. mulatta 95.5 1259

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; uncharacterized tissue; mammary gland; lung; skin; spleen; pineal gland; esophagus; bladder; larynx; kidney; trachea; mouth; prostate; intestine; testis; cervix; pancreas; eye; pharynx; heart; mixed; parathyroid; muscle; uterus; stomach; embryonic tissue; thyroid; adipose tissue; thymus; liver; connective tissue; ascites; ganglia; blood; umbilical cord; adrenal gland; vascular; ovary; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p22
UniSTS entry: Chr 8 D8S1412E
UniSTS entry: Chr 8 RH12837 [Map Viewer]
UniSTS entry: Chr 8 SHGC-52401
UniSTS entry: Chr 8 SHGC-57581
UniSTS entry: Chr 8 SHGC-53007
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (30)

AY363099.1 Homo sapiens normal early placenta (NEP) mRNA, partial cds P
AK125188.1 Homo sapiens cDNA FLJ43198 fis, clone FEBRA2007544, highly similar to Homo sapiens mitochondrial tumor suppressor 1 (MTUS1), transcript variant 4, mRNA P
AB033114.1 Homo sapiens mRNA for KIAA1288 protein, partial cds P
AK000172.1 Homo sapiens cDNA FLJ20165 fis, clone COL09466 PA
NM_001001931.2 Homo sapiens microtubule associated tumor suppressor 1 (MTUS1), transcript variant 4, mRNA PA
NM_001001925.2 Homo sapiens microtubule associated tumor suppressor 1 (MTUS1), transcript variant 2, mRNA PA
NM_001001924.2 Homo sapiens microtubule associated tumor suppressor 1 (MTUS1), transcript variant 1, mRNA PA
BC098381.1 Homo sapiens cDNA clone IMAGE:4819473, containing frame-shift errors PA
AK024357.1 Homo sapiens cDNA FLJ14295 fis, clone PLACE1008426, weakly similar to RESTIN P
AK026661.1 Homo sapiens cDNA: FLJ23008 fis, clone LNG00455 A
BC117564.1 Homo sapiens cDNA clone IMAGE:4402466 PA
BC142971.1 Homo sapiens mitochondrial tumor suppressor 1, mRNA (cDNA clone IMAGE:8860393), complete cds PA
BC017740.1 Homo sapiens mitochondrial tumor suppressor 1, mRNA (cDNA clone IMAGE:4186190), with apparent retained intron PA
AF293357.1 Homo sapiens AT2 receptor-interacting protein 1 mRNA, complete cds P
NM_020749.4 Homo sapiens microtubule associated tumor suppressor 1 (MTUS1), nuclear gene encoding mitochondrial protein, transcript variant 5, mRNA PA
AF121259.1 Homo sapiens transcription factor MTSG1 mRNA, complete cds PA
AF394227.1 Homo sapiens erythroid differentiation-related mRNA, 3' UTR
AK289750.1 Homo sapiens cDNA FLJ78313 complete cds, highly similar to Homo sapiens mitochondrial tumor suppressor 1 (MTUS1), transcript variant 5, mRNA P
AK310871.1 Homo sapiens cDNA, FLJ17913 P
AK314692.1 Homo sapiens cDNA, FLJ95546, highly similar to Homo sapiens mitochondrial tumor suppressor gene 1 (MTSG1), mRNA P
BC033842.1 Homo sapiens mitochondrial tumor suppressor 1, mRNA (cDNA clone IMAGE:3921139), complete cds PA
AK304105.1 Homo sapiens cDNA FLJ53273 complete cds, highly similar to Homo sapiens mitochondrial tumor suppressor 1 (MTUS1), transcript variant 2, mRNA P
AK294860.1 Homo sapiens cDNA FLJ59507 complete cds, highly similar to Homo sapiens mitochondrial tumor suppressor 1 (MTUS1), transcript variant 4, mRNA P
BC007328.2 Homo sapiens mitochondrial tumor suppressor 1, mRNA (cDNA clone IMAGE:3835953), partial cds PA
AF086371.1 Homo sapiens full length insert cDNA clone ZD67D11 PA
BC171765.1 Homo sapiens cDNA clone IMAGE:9054419, containing frame-shift errors P
FJ458441.1 Homo sapiens mitochondrial tumor suppressor 1 variant 1 (MTUS1) mRNA, 5' UTR; nuclear gene for mitochondrial product
FJ458440.1 Homo sapiens mitochondrial tumor suppressor 1 variant 1 (MTUS1) mRNA, 5' UTR; nuclear gene for mitochondrial product
BC136320.1 Homo sapiens mitochondrial tumor suppressor 1, mRNA (cDNA clone MGC:167930 IMAGE:9020307), complete cds P
NM_001166393.1 Homo sapiens microtubule associated tumor suppressor 1 (MTUS1), transcript variant 6, mRNA PA

EST sequences (10 of 704) [Show all sequences]

AA974079.1 Clone IMAGE:1586224 uncharacterized tissue 3' read A
AA984267.1 Clone IMAGE:1629706 brain 3' read P
AI017448.1 Clone IMAGE:1635715 kidney 3' read A
AI028661.1 Clone IMAGE:1644410 testis 3' read
AI031772.1 Clone IMAGE:1649929 parathyroid 3' read A
AI038482.1 Clone IMAGE:1647849 parathyroid 3' read A
AI038841.1 Clone IMAGE:1659583 embryonic tissue 3' read A
AA928641.1 Clone IMAGE:1553030 uncharacterized tissue 3' read
AI125878.1 Clone IMAGE:1737338 testis 3' read A
CB051840.1 Clone IMAGE:3289922 uncharacterized tissue 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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