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UGID:140314     UniGene Hs.79064     Homo sapiens (human)   DHPS
Deoxyhypusine synthase (DHPS)

Human protein-coding gene DHPS. Represented by 579 ESTs from 229 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 140314 - Hs.79064]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001169027.1 PREDICTED: deoxyhypusine synthase isoform 7 P. troglodytes 100.0 368
NP_001921.1 DHPS gene product H. sapiens 100.0 368
NP_001034603.1 Dhps gene product M. musculus 95.9 368
XP_002661151.2 PREDICTED: deoxyhypusine synthase-like D. rerio 85.2 358
NP_001084929.1 deoxyhypusine synthase X. laevis 81.9 342
NP_648188.2 CG8005, isoform A D. melanogaster 72.2 356
XP_001689942.1 deoxypusine synthase 1 C. reinhardtii 71.4 360
NP_196211.1 deoxyhypusine synthase A. thaliana 70.0 356
XP_963241.1 deoxyhypusine synthase N. crassa 69.1 350
NP_011935.1 Dys1p S. cerevisiae 68.9 363
NP_496557.1 Protein DHPS-1 C. elegans 68.4 366
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_001108116.1 PREDICTED: deoxyhypusine synthase isoform 4 M. mulatta 98.6 368
XP_003915030.1 PREDICTED: deoxyhypusine synthase isoform 1 P. anubis 98.4 368

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; eye; uncharacterized tissue; vascular; mouth; uterus; ovary; blood; thymus; testis; bone marrow; stomach; prostate; mixed; embryonic tissue; bladder; placenta; intestine; muscle; pancreas; spleen; kidney; skin; heart; ear; ascites; connective tissue; cervix; lymph; liver; bone; adrenal gland; mammary gland; nerve; tonsil; pituitary gland; thyroid; pharynx; ganglia; adipose tissue; lymph node; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.2
UniSTS entry: Chr 19 D19S623E
UniSTS entry: Chr 19 D19S677E
UniSTS entry: Chr 19 WI-19573 [Map Viewer]
UniSTS entry: Chr 1 D1S3693
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_001930.3 Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 1, mRNA PA
NM_013406.2 Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 2, mRNA PA
L39068.1 Human deoxyhypusine synthase mRNA, complete cds P
AY336090.1 Homo sapiens migration-inducing gene 13 mRNA, complete cds P
U40579.1 Human deoxyhypusine synthase mRNA, complete cds PA
BC000333.2 Homo sapiens deoxyhypusine synthase, mRNA (cDNA clone MGC:8526 IMAGE:2822554), complete cds PA
BC128553.1 Homo sapiens cDNA clone IMAGE:40122362
BC014016.2 Homo sapiens deoxyhypusine synthase, mRNA (cDNA clone MGC:20308 IMAGE:4129051), complete cds PA
AK291553.1 Homo sapiens cDNA FLJ75710 complete cds, highly similar to Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 1, mRNA P
U26266.1 Human deoxyhypusine synthase mRNA, complete cds P
AK300498.1 Homo sapiens cDNA FLJ59986 complete cds, moderately similar to Deoxyhypusine synthase (EC 2.5.1.46) P
AK304780.1 Homo sapiens cDNA FLJ53702 complete cds, highly similar to Deoxyhypusine synthase (EC 2.5.1.46) P
U79262.1 Human deoxyhypusine synthase mRNA, complete cds PA
NM_001206974.1 Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 4, mRNA PA
NR_038192.1 Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 5, non-coding RNA PA
U32178.1 Human deoxyhypusine synthase 2 mRNA, complete cds P

EST sequences (10 of 579) [Show all sequences]

AA972040.1 Clone IMAGE:1583936 mixed 3' read P
AI014330.1 Clone IMAGE:1539073 brain 3' read
R21131.1 Clone IMAGE:36409 brain 5' read
AI123978.1 Clone IMAGE:1694886 uterus 3' read
CB047312.1 Clone IMAGE:3253137 kidney 5' read A
CB050790.1 Clone IMAGE:3271981 prostate 3' read A
BX089336.1 Clone IMAGp998J06140_;_IMAGE:26908 brain PA
AI263977.1 Clone IMAGE:1874924 intestine 3' read P
CB112342.1 Clone L6ChoCK0-5-B12 liver 5' read P
CB154574.1 Clone B2N807043-28-E10 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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