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UGID:130839     UniGene Hs.789     Homo sapiens (human)   CXCL1
Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1)

Human protein-coding gene CXCL1. Represented by 138 ESTs from 72 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 130839 - Hs.789]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001156094.1 PREDICTED: uncharacterized protein LOC740567 isoform 2 P. troglodytes 100.0 106
NP_001502.1 CXCL1 gene product H. sapiens 100.0 106
Other hits (2 of 7) [Show all]SpeciesId(%)Len(aa)
NP_001028050.1 CXCL1 gene product M. mulatta 90.7 106
XP_003898819.1 PREDICTED: growth-regulated alpha protein P. anubis 90.7 106

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; mammary gland; skin; intestine; vascular; liver; mixed; bladder; eye; heart; prostate; cervix; trachea; ascites; stomach; placenta; connective tissue; uncharacterized tissue; blood; ovary; pancreas; lymph node; uterus; thyroid; brain; esophagus; kidney; mouth
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21
UniSTS entry: Chr 4 SHGC-67281 [Map Viewer]
UniSTS entry: Chr 4 RH17698
UniSTS entry: Chr 4 D4S2819 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

J03561.1 Human gro (growth regulated) gene P
BT006880.1 Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) mRNA, complete cds P
NM_001511.3 Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1), transcript variant 1, mRNA PA
X12510.1 Human mRNA for melanoma growth stimulatory activity (MGSA) P
BC011976.1 Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), mRNA (cDNA clone MGC:9049 IMAGE:3856841), complete cds PA
NR_046035.1 Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1), transcript variant 2, non-coding RNA PA

EST sequences (10 of 138) [Show all sequences]

AI148274.1 Clone IMAGE:1680576 skin 3' read A
BX114964.1 Clone IMAGp998B07732_;_IMAGE:323238 skin A
AI254241.1 Clone IMAGE:1962555 intestine 3' read A
CB112830.1 Clone L6ChoCK0-9-A06 liver 5' read P
CB136983.1 Clone L6ChoCK0-23-G08 liver 5' read
CB134631.1 Clone L14ChoiCK0-15-B04 liver 5' read A
CB135490.1 Clone L14ChoiCK0-29-F12 liver 5' read A
CB149087.1 Clone L15CKK1-39-H09 liver 5' read P
CB152543.1 Clone L15CKK1s1-1-E10 liver 5' read
AI302652.1 Clone IMAGE:1901455 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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