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UGID:140235     UniGene Hs.78601     Homo sapiens (human)   UROD
Uroporphyrinogen decarboxylase (UROD)

Human protein-coding gene UROD. Represented by 848 ESTs from 297 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 140235 - Hs.78601]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_513127.1 PREDICTED: uroporphyrinogen decarboxylase isoform 9 P. troglodytes 100.0 366
NP_000365.3 UROD gene product H. sapiens 100.0 366
NP_033504.2 Urod gene product M. musculus 96.7 366
NP_001084556.1 uroporphyrinogen decarboxylase X. laevis 78.0 363
NP_571422.1 urod gene product D. rerio 77.3 364
NP_610501.1 updo, isoform A D. melanogaster 61.4 352
NP_010332.3 uroporphyrinogen decarboxylase HEM12 S. cerevisiae 57.3 356
XP_964266.2 uroporphyrinogen decarboxylase N. crassa 56.6 364
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_003891828.1 PREDICTED: uroporphyrinogen decarboxylase P. anubis 99.5 366
XP_002808261.1 PREDICTED: LOW QUALITY PROTEIN: uroporphyrinogen decarboxylase-like M. mulatta 99.2 366

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; kidney; prostate; skin; liver; muscle; testis; placenta; uterus; embryonic tissue; uncharacterized tissue; intestine; heart; bone; bone marrow; lymph; blood; tonsil; salivary gland; spleen; thyroid; eye; pharynx; pancreas; parathyroid; pituitary gland; esophagus; bladder; mammary gland; ovary; connective tissue; adrenal gland; thymus; vascular; ascites; umbilical cord; ganglia; nerve; cervix; lymph node; stomach; mouth; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p34
UniSTS entry: Chr 1 RH78894 [Map Viewer]
UniSTS entry: Chr 1 MARC_6909-6910:996689833:1
UniSTS entry: Chr 1 SHGC-74688 [Map Viewer]
UniSTS entry: Chr 1 WI-18590 [Map Viewer]
UniSTS entry: Chr 1 MARC_14579-14580:1009487818:7
UniSTS entry: MARC_2803-2804:991933440:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (37)

AF104421.1 Homo sapiens isolate normal patient 1 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104422.1 Homo sapiens isolate normal patient 2 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104423.1 Homo sapiens isolate normal patient 3 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104424.1 Homo sapiens isolate normal patient 4 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104425.1 Homo sapiens isolate normal patient 5 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104426.1 Homo sapiens isolate normal patient 6 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104427.1 Homo sapiens isolate normal patient 7 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104428.1 Homo sapiens isolate normal patient 8 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104429.1 Homo sapiens isolate normal patient 9 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104430.1 Homo sapiens isolate normal patient 10 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104431.1 Homo sapiens isolate sporadic PCT patient 1 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104432.1 Homo sapiens isolate sporadic PCT patient 2 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104433.1 Homo sapiens isolate sporadic PCT patient 3 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104434.1 Homo sapiens isolate sporadic PCT patient 4 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104435.1 Homo sapiens isolate sporadic PCT patient 5 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104436.1 Homo sapiens isolate sporadic PCT patient 6 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104437.1 Homo sapiens isolate sporadic PCT patient 7 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104438.1 Homo sapiens isolate sporadic PCT patient 8 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104439.1 Homo sapiens isolate sporadic PCT patient 9 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
AF104440.1 Homo sapiens isolate sporadic PCT patient 10 uroporphyrinogen decarboxylase (UROD) mRNA, complete cds P
BT006737.1 Homo sapiens uroporphyrinogen decarboxylase mRNA, complete cds P
BX647308.1 Homo sapiens mRNA; cDNA DKFZp686O11196 (from clone DKFZp686O11196) PA
NM_000374.4 Homo sapiens uroporphyrinogen decarboxylase (UROD), transcript variant 1, mRNA P
CR456976.1 Homo sapiens full open reading frame cDNA clone RZPDo834C065D for gene UROD, uroporphyrinogen decarboxylase; complete cds, incl. stopcodon P
CR542057.1 Homo sapiens full open reading frame cDNA clone RZPDo834A1036D for gene UROD, uroporphyrinogen decarboxylase; complete cds, without stopcodon P
BC001778.1 Homo sapiens uroporphyrinogen decarboxylase, mRNA (cDNA clone MGC:1856 IMAGE:3542421), complete cds PA
AK225053.1 Homo sapiens mRNA for uroporphyrinogen decarboxylase variant, clone: adSH01242 PA
M14016.1 Human uroporphyrinogen decarboxylase mRNA, complete cds P
AK291877.1 Homo sapiens cDNA FLJ76900 complete cds, highly similar to Homo sapiens uroporphyrinogen decarboxylase (UROD), mRNA PA
AK308996.1 Homo sapiens cDNA, FLJ99037 P
AK310208.1 Homo sapiens cDNA, FLJ17250 P
AK315878.1 Homo sapiens cDNA, FLJ79527 complete cds, moderately similar to Uroporphyrinogen decarboxylase (EC 4.1.1.37) P
AK309724.1 Homo sapiens cDNA, FLJ99765 P
AK309446.1 Homo sapiens cDNA, FLJ99487 P
AK293702.1 Homo sapiens cDNA FLJ50456 complete cds, highly similar to Uroporphyrinogen decarboxylase (EC 4.1.1.37) P
AK295284.1 Homo sapiens cDNA FLJ59203 complete cds, moderately similar to Uroporphyrinogen decarboxylase (EC 4.1.1.37) P
NR_036510.1 Homo sapiens uroporphyrinogen decarboxylase (UROD), transcript variant 2, non-coding RNA P

EST sequences (10 of 848) [Show all sequences]

AA962840.1 Clone IMAGE:1573768 kidney 3' read A
AA972495.1 Clone IMAGE:1575736 intestine 3' read P
AA995944.1 Clone IMAGE:1635830 kidney 3' read PA
R17306.1 Clone IMAGE:32062 brain 5' read
AI003541.1 Clone IMAGE:1699152 kidney 3' read PA
AI015233.1 Clone IMAGE:1624102 embryonic tissue 3' read A
AI015538.1 Clone IMAGE:1636073 kidney 3' read PA
AA929038.1 Clone IMAGE:1565225 mixed 3' read A
AI031682.1 Clone IMAGE:1650116 parathyroid 3' read PA
AI039578.1 Clone IMAGE:1664630 skin 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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