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UGID:140022     UniGene Hs.76753     Homo sapiens (human)   ENG
Endoglin (ENG)

Human protein-coding gene ENG. Represented by 2228 ESTs from 325 cDNA libraries. EST representation biased toward neonate. Corresponds to 2 reference sequences (different isoforms). [UniGene 140022 - Hs.76753]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001108225.1 ENG gene product H. sapiens 100.0 657
NP_001139820.1 Eng gene product M. musculus 78.2 651
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_001143396.3 PREDICTED: endoglin P. troglodytes 98.0 606
XP_002803157.1 PREDICTED: 6-phosphofructokinase, liver type-like M. mulatta 97.3 74

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; placenta; lung; vascular; spleen; connective tissue; kidney; thymus; skin; uncharacterized tissue; uterus; intestine; heart; mixed; mouth; prostate; pancreas; mammary gland; eye; thyroid; adrenal gland; liver; nerve; blood; ovary; embryonic tissue; trachea; stomach; bone marrow; salivary gland; bone; lymph node; umbilical cord; muscle; pituitary gland; larynx; esophagus; cervix; parathyroid; adipose tissue; ganglia; epididymis
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q34.11
UniSTS entry: Chr 9 RH68386 [Map Viewer]
UniSTS entry: Chr 9 STS-J05481
UniSTS entry: Chr 9 RH80829
UniSTS entry: Chr 9 STS-AA035463
UniSTS entry: Chr 9 RH79931
UniSTS entry: Chr 9 GDB:553329
UniSTS entry: Chr 9 GDB:553296
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT006872.1 Homo sapiens endoglin (Osler-Rendu-Weber syndrome 1) mRNA, complete cds P
NM_000118.2 Homo sapiens endoglin (ENG), transcript variant 2, mRNA PA
AK223044.1 Homo sapiens mRNA for ENG protein (Endoglin) (Osler-Rendu-Weber syndrome 1) variant, clone: JTH14476 PA
AK222669.1 Homo sapiens mRNA, endoglin precursor variant, clone: CBR00310 PA
BC014271.2 Homo sapiens endoglin, mRNA (cDNA clone MGC:10516 IMAGE:3843174), complete cds PA
AK290389.1 Homo sapiens cDNA FLJ75401 complete cds, highly similar to Homo sapiens endoglin (Osler-Rendu-Weber syndrome 1), mRNA P
NM_001114753.1 Homo sapiens endoglin (ENG), transcript variant 1, mRNA PA
X72012.1 H.sapiens end mRNA for endoglin PA
AK300156.1 Homo sapiens cDNA FLJ57432 complete cds, highly similar to Endoglin precursor P
AK302455.1 Homo sapiens cDNA FLJ57670 complete cds, highly similar to Endoglin precursor P
BC020391.1 Homo sapiens endoglin, mRNA (cDNA clone IMAGE:3446536) P
AK301171.1 Homo sapiens cDNA FLJ58696 complete cds, highly similar to Endoglin precursor P
J05481.1 Human endoglin mRNA, 3' end PA

EST sequences (10 of 2228) [Show all sequences]

AA954162.1 Clone IMAGE:1591326 kidney 3' read A
AA970185.1 Clone IMAGE:1581269 mixed 3' read P
AA973331.1 Clone IMAGE:1584254 mixed 3' read P
AA976943.1 Clone IMAGE:1587896 uncharacterized tissue 3' read A
AA977727.1 Clone IMAGE:1589523 kidney 3' read P
AA987682.1 Clone IMAGE:1593394 kidney 3' read A
AA987819.1 Clone IMAGE:1588867 kidney 3' read P
AA993589.1 Clone IMAGE:1619667 testis 3' read A
AA906156.1 Clone IMAGE:1504863 mixed 3' read
AA922846.1 Clone IMAGE:1457363 intestine 3' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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