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UGID:139892     UniGene Hs.75694     Homo sapiens (human)   MPI
Mannose phosphate isomerase (MPI)

Human protein-coding gene MPI. Represented by 722 ESTs from 286 cDNA libraries. Corresponds to reference sequence NM_002435.1. [UniGene 139892 - Hs.75694]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002426.1 MPI gene product H. sapiens 100.0 422
NP_001092020.1 MPI gene product P. troglodytes 99.8 422
NP_080113.1 Mpi gene product M. musculus 90.3 422
NP_001028282.1 mpi gene product D. rerio 72.0 421
XP_957390.1 mannose-6-phosphate isomerase N. crassa 51.5 326
NP_010918.1 mannose-6-phosphate isomerase PMI40 S. cerevisiae 51.0 316
NP_176878.1 mannose-6-phosphate isomerase A. thaliana 49.1 322
NP_499174.3 Protein ZK632.4 C. elegans 47.8 293
XP_001695020.1 mannose-6-phosphate isomerase C. reinhardtii 46.1 232
NP_649940.1 CG8417 D. melanogaster 45.5 198
Other hits (2 of 54) [Show all]SpeciesId(%)Len(aa)
XP_003901264.1 PREDICTED: mannose-6-phosphate isomerase P. anubis 98.6 424
XP_001098369.1 PREDICTED: mannose-6-phosphate isomerase-like isoform 1 M. mulatta 98.4 245

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; intestine; placenta; lung; liver; lymph; mouth; salivary gland; umbilical cord; connective tissue; nerve; adrenal gland; spleen; thymus; mixed; mammary gland; kidney; stomach; heart; prostate; lymph node; uterus; pharynx; cervix; muscle; blood; skin; eye; embryonic tissue; ovary; adipose tissue; esophagus; pituitary gland; bladder; trachea; thyroid; bone; ascites; pancreas; vascular; pineal gland; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q22-qter
UniSTS entry: Chr 15 STS-X76057
UniSTS entry: Chr 15 WI-19219 [Map Viewer]
UniSTS entry: Chr 15 D15S1167 [Map Viewer]
UniSTS entry: Chr 15 WI-21454 [Map Viewer]
UniSTS entry: Chr 15 RH15703
UniSTS entry: Chr 15 WI-15741 [Map Viewer]
UniSTS entry: Chr 15 MPI__6336
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BC046357.1 Homo sapiens mannose phosphate isomerase, mRNA (cDNA clone MGC:49923 IMAGE:5745956), complete cds PA
BX648475.1 Homo sapiens mRNA; cDNA DKFZp686P11156 (from clone DKFZp686P11156) PA
NM_002435.1 Homo sapiens mannose phosphate isomerase (MPI), mRNA P
AK225149.1 Homo sapiens mRNA for mannose-6- phosphate isomerase variant, clone: CBL06427 PA
BC017351.2 Homo sapiens mannose phosphate isomerase, mRNA (cDNA clone MGC:29577 IMAGE:5013257), complete cds PA
AK292374.1 Homo sapiens cDNA FLJ76937 complete cds, highly similar to Homo sapiens mannose phosphate isomerase (MPI), mRNA P
AF504648.1 Homo sapiens tissue-type brain mannose phosphate isomerase isoform mRNA, complete cds PA
AK096520.1 Homo sapiens cDNA FLJ39201 fis, clone OCBBF2005349, weakly similar to MANNOSE-6-PHOSPHATE ISOMERASE (EC 5.3.1.8) P
AK301370.1 Homo sapiens cDNA FLJ59446 complete cds, highly similar to Mannose-6-phosphate isomerase (EC 5.3.1.8) P
AK294030.1 Homo sapiens cDNA FLJ56688 complete cds, highly similar to Mannose-6-phosphate isomerase (EC 5.3.1.8) P
AK302354.1 Homo sapiens cDNA FLJ54812 complete cds, moderately similar to Mannose-6-phosphate isomerase (EC 5.3.1.8) P
X76057.1 H.sapiens PMI1 mRNA for phosphomannose isomerase P

EST sequences (10 of 722) [Show all sequences]

AA954638.1 Clone IMAGE:1554890 kidney 3' read A
AA971273.1 Clone IMAGE:1574912 kidney 3' read A
AA973383.1 Clone IMAGE:1568970 lung 3' read
AA983694.1 Clone IMAGE:1557594 lung 3' read A
AA948176.1 Clone IMAGE:1588144 uncharacterized tissue 3' read A
AI092362.1 Clone IMAGE:1692969 heart 3' read
AI125402.1 Clone IMAGE:1737018 testis 3' read A
AI150887.1 Clone IMAGE:1703364 brain 3' read A
AI086383.1 Clone IMAGE:1678190 mixed 3' read A
BX102531.1 Clone IMAGp998P20623_;_IMAGE:281731 brain P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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