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UGID:6126515     UniGene Hs.744182     Homo sapiens (human)   KLF2
Kruppel-like factor 2 (lung) (KLF2)

Human protein-coding gene KLF2. Represented by 447 ESTs from 67 cDNA libraries. EST representation biased toward leukemia. Corresponds to reference sequence NM_016270.2. [UniGene 6126515 - Hs.744182]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_057354.1 KLF2 gene product H. sapiens 100.0 354
NP_032478.2 Klf2 gene product M. musculus 91.0 353
NP_611747.2 CG42741 D. melanogaster 75.3 88
NP_001022204.1 Protein KLF-3, isoform a C. elegans 67.0 106
NP_001080430.1 Kruppel-like factor 2 (lung) X. laevis 63.8 372
NP_571932.1 klf2b gene product D. rerio 62.3 357
Other hits (2 of 40) [Show all]SpeciesId(%)Len(aa)
XP_003316222.1 PREDICTED: Krueppel-like factor 2 P. troglodytes 99.4 354
XP_001787418.2 PREDICTED: Krueppel-like factor 2 B. taurus 98.6 146

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: leukemia [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; lung; pancreas; mixed; kidney; heart; cervix; placenta; brain; prostate; mammary gland; ovary; skin; intestine; mouth; nerve; blood; connective tissue; eye; bone marrow; lymph node; stomach; embryonic tissue; muscle; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.11
UniSTS entry: Chr 19 KLF2
UniSTS entry: Chr 19 RH98967
UniSTS entry: Chr 19 SHGC-57513
UniSTS entry: Chr 19 RH41932
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BC071983.1 Homo sapiens Kruppel-like factor 2 (lung), mRNA (cDNA clone MGC:88680 IMAGE:5480246), complete cds PA
NM_016270.2 Homo sapiens Kruppel-like factor 2 (lung) (KLF2), mRNA PA
AF134053.1 Homo sapiens Kruppel-like factor LKLF mRNA, complete cds P
AF205849.1 Homo sapiens Kruppel-like factor mRNA, complete cds P
AK225820.1 Homo sapiens mRNA for Kruppel-like factor variant, clone: FCC128H02 PA
BC035342.1 Homo sapiens, Similar to Kruppel-like factor 2 (lung), clone IMAGE:5181011, mRNA, partial cds P

EST sequences (10 of 447) [Show all sequences]

AA863328.1 Clone IMAGE:1456789 kidney 3' read A
AA962275.1 Clone IMAGE:1602167 lung 3' read
AA962302.1 Clone IMAGE:1569906 lung 3' read
AA902268.1 Clone IMAGE:1522823 lung 3' read
AA907410.1 Clone IMAGE:1521745 lung 3' read
AA910819.1 Clone IMAGE:1520905 lung 3' read P
AI005011.1 Clone IMAGE:1625583 mixed 3' read P
AI028012.1 Clone IMAGE:1671432 uncharacterized tissue 3' read P
AI027839.1 Clone IMAGE:1671600 uncharacterized tissue 3' read P
AI032538.1 Clone IMAGE:1654779 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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