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UGID:3880000     UniGene Hs.720221     Homo sapiens (human)   PRICKLE1
Prickle homolog 1 (Drosophila) (PRICKLE1)

Human protein-coding gene PRICKLE1. Represented by 223 ESTs from 113 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 3880000 - Hs.720221]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001166762.1 PREDICTED: prickle-like protein 1 isoform 5 P. troglodytes 100.0 830
NP_694571.2 PRICKLE1 gene product H. sapiens 100.0 830
XP_002798580.1 PREDICTED: prickle-like protein 1-like isoform 1 M. mulatta 99.9 830
XP_003906266.1 PREDICTED: prickle-like protein 1 isoform 1 P. anubis 99.6 830
NP_001028389.1 Prickle1 gene product M. musculus 96.0 831
NP_001082157.1 prickle-like protein 1-A X. laevis 85.6 834
NP_899185.2 prickle1a gene product D. rerio 77.5 784
NP_524990.1 espinas, isoform B D. melanogaster 70.5 352
NP_741435.2 Protein PRKL-1, isoform a C. elegans 52.1 330
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003640013.1 PREDICTED: prickle-like protein 1-like C. lupus familiaris 98.3 831
XP_001488253.1 PREDICTED: prickle-like protein 1 E. caballus 98.3 831

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mammary gland; embryonic tissue; ovary; placenta; thyroid; bone marrow; uterus; connective tissue; spleen; trachea; skin; thymus; eye; mixed; muscle; kidney; heart; lung; vascular; liver; prostate; stomach; intestine; ear; lymph; bone; ganglia; pancreas; nerve
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q12
UniSTS entry: Chr 12 D12S1781 [Map Viewer]
UniSTS entry: Chr 12 RH78229
UniSTS entry: Chr 12 WI-15796 [Map Viewer]
UniSTS entry: Chr 12 STS-N30055
UniSTS entry: Chr 12 PRICKLE1
UniSTS entry: Chr 12 PRICKLE1__5577
UniSTS entry: Chr 1 D11S2921
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK122881.1 Homo sapiens cDNA FLJ16528 fis, clone OCBBF2010841, highly similar to Prickle-like protein 1 P
AK122877.1 Homo sapiens cDNA FLJ16519 fis, clone NT2RI3007684, highly similar to Prickle-like protein 1 P
AF399844.1 Homo sapiens REST/NRSF-interacting lim domain protein (RILP) mRNA, complete cds PA
AF543760.1 Homo sapiens REST/NRSF-interacting LIM domain protein (RILP) mRNA, 5' UTR B and partial cds P
AF543759.1 Homo sapiens REST/NRSF-interacting LIM domain protein (RILP) mRNA, 5' UTR C and partial cds P
AK021728.1 Homo sapiens cDNA FLJ11666 fis, clone HEMBA1004672
BC114940.1 Homo sapiens prickle homolog 1 (Drosophila), mRNA (cDNA clone MGC:138903 IMAGE:40084893), complete cds P
BC114939.1 Homo sapiens prickle homolog 1 (Drosophila), mRNA (cDNA clone MGC:138902 IMAGE:40084889), complete cds P
AK056499.1 Homo sapiens cDNA FLJ31937 fis, clone NT2RP7006527, moderately similar to LIM-ONLY PROTEIN 6 P
AK056189.1 Homo sapiens cDNA FLJ31627 fis, clone NT2RI2003338 P
AK096233.1 Homo sapiens cDNA FLJ38914 fis, clone NT2NE2008639
NM_001144883.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 4, mRNA PA
NM_001144882.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 3, mRNA PA
NM_001144881.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 2, mRNA PA
NM_153026.2 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 1, mRNA PA

EST sequences (10 of 223) [Show all sequences]

AA903424.1 Clone IMAGE:1517151 uncharacterized tissue 3' read A
AI028542.1 Clone IMAGE:1645562 testis 3' read
AI095049.1 Clone IMAGE:1686314 brain 3' read A
AI127699.1 Clone IMAGE:1710762 uterus 3' read
AI139257.1 Clone IMAGE:1710112 heart 3' read
AI142455.1 Clone IMAGE:1697475 uterus 3' read
AI160075.1 Clone IMAGE:1708992 heart 3' read
BX115680.1 Clone IMAGp998K181162_;_IMAGE:488585 uterus A
CB120645.1 Clone L8SCK0-36-D02 liver 5' read P
CB134289.1 Clone L14ChoiCK0-12-B06 liver 5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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