NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:3880000     UniGene Hs.720221     Homo sapiens (human)   PRICKLE1
Prickle homolog 1 (Drosophila) (PRICKLE1)

Human protein-coding gene PRICKLE1. Represented by 223 ESTs from 113 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 3880000 - Hs.720221]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001166762.1 PREDICTED: prickle-like protein 1 isoform 5 P. troglodytes 100.0 830
NP_694571.2 PRICKLE1 gene product H. sapiens 100.0 830
XP_002798580.1 PREDICTED: prickle-like protein 1-like isoform 1 M. mulatta 99.9 830
XP_003906266.1 PREDICTED: prickle-like protein 1 isoform 1 P. anubis 99.6 830
NP_001028389.1 Prickle1 gene product M. musculus 96.0 831
NP_001082157.1 prickle-like protein 1-A X. laevis 85.6 834
NP_899185.2 prickle1a gene product D. rerio 77.5 784
NP_524990.1 espinas, isoform B D. melanogaster 70.5 352
NP_741435.2 Protein PRKL-1, isoform a C. elegans 52.1 330
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003640013.1 PREDICTED: prickle-like protein 1-like C. lupus familiaris 98.3 831
XP_001488253.1 PREDICTED: prickle-like protein 1 E. caballus 98.3 831

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mammary gland; embryonic tissue; ovary; placenta; thyroid; bone marrow; uterus; connective tissue; spleen; trachea; skin; thymus; eye; mixed; muscle; kidney; heart; lung; vascular; liver; prostate; stomach; intestine; ear; lymph; bone; ganglia; pancreas; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q12
UniSTS entry: Chr 12 D12S1781 [Map Viewer]
UniSTS entry: Chr 12 RH78229
UniSTS entry: Chr 12 WI-15796 [Map Viewer]
UniSTS entry: Chr 12 STS-N30055
UniSTS entry: Chr 12 PRICKLE1
UniSTS entry: Chr 12 PRICKLE1__5577
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK122881.1 Homo sapiens cDNA FLJ16528 fis, clone OCBBF2010841, highly similar to Prickle-like protein 1 P
AK122877.1 Homo sapiens cDNA FLJ16519 fis, clone NT2RI3007684, highly similar to Prickle-like protein 1 P
AF399844.1 Homo sapiens REST/NRSF-interacting lim domain protein (RILP) mRNA, complete cds PA
AF543760.1 Homo sapiens REST/NRSF-interacting LIM domain protein (RILP) mRNA, 5' UTR B and partial cds P
AF543759.1 Homo sapiens REST/NRSF-interacting LIM domain protein (RILP) mRNA, 5' UTR C and partial cds P
AK021728.1 Homo sapiens cDNA FLJ11666 fis, clone HEMBA1004672
BC114940.1 Homo sapiens prickle homolog 1 (Drosophila), mRNA (cDNA clone MGC:138903 IMAGE:40084893), complete cds P
BC114939.1 Homo sapiens prickle homolog 1 (Drosophila), mRNA (cDNA clone MGC:138902 IMAGE:40084889), complete cds P
AK056499.1 Homo sapiens cDNA FLJ31937 fis, clone NT2RP7006527, moderately similar to LIM-ONLY PROTEIN 6 P
AK056189.1 Homo sapiens cDNA FLJ31627 fis, clone NT2RI2003338 P
AK096233.1 Homo sapiens cDNA FLJ38914 fis, clone NT2NE2008639
NM_001144883.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 4, mRNA PA
NM_001144882.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 3, mRNA PA
NM_001144881.1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 2, mRNA PA
NM_153026.2 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 1, mRNA PA

EST sequences (10 of 223) [Show all sequences]

AA903424.1 Clone IMAGE:1517151 uncharacterized tissue 3' read A
AI028542.1 Clone IMAGE:1645562 testis 3' read
AI095049.1 Clone IMAGE:1686314 brain 3' read A
AI127699.1 Clone IMAGE:1710762 uterus 3' read
AI139257.1 Clone IMAGE:1710112 heart 3' read
AI142455.1 Clone IMAGE:1697475 uterus 3' read
AI160075.1 Clone IMAGE:1708992 heart 3' read
BX115680.1 Clone IMAGp998K181162_;_IMAGE:488585 uterus A
CB120645.1 Clone L8SCK0-36-D02 liver 5' read P
CB134289.1 Clone L14ChoiCK0-12-B06 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help