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UGID:3349708     UniGene Hs.712553     Homo sapiens (human)   MS4A1
Membrane-spanning 4-domains, subfamily A, member 1 (MS4A1)

Human protein-coding gene MS4A1. Represented by 271 ESTs from 53 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 3349708 - Hs.712553]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_068769.2 MS4A1 gene product H. sapiens 100.0 296
NP_031667.1 Ms4a1 gene product M. musculus 77.7 290
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
XP_001139556.1 PREDICTED: B-lymphocyte antigen CD20 isoform 1 P. troglodytes 99.3 296
XP_001086364.1 PREDICTED: b-lymphocyte antigen CD20 isoform 3 M. mulatta 98.0 296

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lymph node; spleen; blood; thymus; intestine; pharynx; connective tissue; lung; prostate; uncharacterized tissue; mixed; mammary gland; pancreas; brain; lymph; vascular; testis; parathyroid; skin; kidney; trachea; stomach; tonsil
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q12
UniSTS entry: Chr 11 RH93627
UniSTS entry: Chr 11 SHGC-60212
UniSTS entry: Chr 11 SHGC-133022
UniSTS entry: Chr 11 D11S4377
UniSTS entry: Chr 11 RH11466 [Map Viewer]
UniSTS entry: Chr 11 STS-L23419
UniSTS entry: Chr 11 RH93595
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_021950.3 Homo sapiens membrane-spanning 4-domains, subfamily A, member 1 (MS4A1), transcript variant 3, mRNA P
BC002807.2 Homo sapiens membrane-spanning 4-domains, subfamily A, member 1, mRNA (cDNA clone MGC:3969 IMAGE:3634040), complete cds PA
AK225630.1 Homo sapiens mRNA for membrane-spanning 4-domains, subfamily A, member 1 variant, clone: SPL06949 PA
AK292168.1 Homo sapiens cDNA FLJ76926 complete cds, highly similar to Homo sapiens membrane-spanning 4-domains, subfamily A, member 1(MS4A1), transcript variant 3, mRNA P
AK310118.1 Homo sapiens cDNA, FLJ17160 P
X12530.1 Human mRNA for B lymphocyte antigen CD20 (B1, Bp35) P
X07203.1 Human mRNA for CD20 receptor (S7) P
AK300025.1 Homo sapiens cDNA FLJ51650 complete cds, moderately similar to B-lymphocyte antigen CD20 P
X07204.1 Human mRNA for CD20 receptor (10.20) 5'-end
NM_152866.2 Homo sapiens membrane-spanning 4-domains, subfamily A, member 1 (MS4A1), transcript variant 1, mRNA P

EST sequences (10 of 271) [Show all sequences]

AI004799.1 Clone IMAGE:1626113 mixed 3' read
AI080700.1 Clone IMAGE:1678466 mixed 3' read A
BX097504.1 Clone IMAGp998D14687_;_IMAGE:306013 parathyroid
BX092708.1 Clone IMAGp998L081724_;_IMAGE:704407 lymph node
AI253701.1 Clone IMAGE:2032133 prostate 3' read
AI224077.1 Clone IMAGE:2001211 lymph node 3' read
AI281592.1 Clone IMAGE:1967938 lymph node 3' read A
AI370360.1 Clone IMAGE:1967761 lymph node 3' read
AI377713.1 Clone IMAGE:2091321 mixed 3' read
AI416965.1 Clone IMAGE:2117071 uncharacterized tissue 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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