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UGID:3124800     UniGene Hs.706355     Homo sapiens (human)   ILK
Integrin-linked kinase (ILK)

Human protein-coding gene ILK. Represented by 620 ESTs from 291 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 3124800 - Hs.706355]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_034692.2 Ilk gene product M. musculus 100.0 451
NP_596900.1 Ilk gene product R. norvegicus 100.0 451
XP_001109041.1 PREDICTED: integrin-linked protein kinase isoform 3 M. mulatta 100.0 451
XP_001164277.2 PREDICTED: integrin-linked protein kinase isoform 1 P. troglodytes 100.0 451
NP_004508.1 ILK gene product H. sapiens 100.0 451
XP_534040.1 PREDICTED: integrin-linked protein kinase isoform 1 C. lupus familiaris 100.0 451
XP_001504649.2 PREDICTED: integrin-linked protein kinase-like isoform 1 E. caballus 100.0 451
XP_003357179.1 PREDICTED: integrin-linked protein kinase S. scrofa 100.0 451
NP_001029865.1 ILK gene product B. taurus 100.0 451
XP_002708812.1 PREDICTED: integrin-linked kinase-like O. cuniculus 100.0 451
NP_001254807.1 ILK gene product O. aries 99.6 451
NP_001085985.1 MGC82989 protein X. laevis 93.6 451
NP_956865.1 ilk gene product D. rerio 92.9 451
NP_525001.2 integrin linked kinase, isoform A D. melanogaster 66.7 447
NP_497139.1 Protein PAT-4 C. elegans 64.7 447
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001363471.1 PREDICTED: integrin-linked protein kinase-like M. domestica 98.5 451
NP_989525.1 ILK gene product G. gallus 95.6 451

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; intestine; mixed; pancreas; uncharacterized tissue; placenta; eye; mouth; uterus; embryonic tissue; stomach; skin; prostate; pituitary gland; blood; testis; lymph; mammary gland; liver; kidney; adipose tissue; thyroid; bone; cervix; muscle; heart; umbilical cord; ovary; bone marrow; spleen; salivary gland; pharynx; connective tissue; larynx; esophagus; ascites; nerve; lymph node; tonsil; thymus; adrenal gland; ganglia; pineal gland; vascular; parathyroid
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.4
UniSTS entry: Chr 11 A002C40
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_004517.2 Homo sapiens integrin-linked kinase (ILK), transcript variant 1, mRNA PA
CR407673.1 Homo sapiens full open reading frame cDNA clone RZPDo834B113D for gene ILK, integrin-linked kinase complete cds, without stopcodon P
CR749220.1 Homo sapiens mRNA; cDNA DKFZp686F1765 (from clone DKFZp686F1765) PA
NM_001014795.1 Homo sapiens integrin-linked kinase (ILK), transcript variant 3, mRNA PA
NM_001014794.1 Homo sapiens integrin-linked kinase (ILK), transcript variant 2, mRNA PA
U40282.1 Homo sapiens integrin-linked kinase (ILK) mRNA, complete cds PA
BC001554.1 Homo sapiens integrin-linked kinase, mRNA (cDNA clone MGC:5051 IMAGE:3457801), complete cds PA
AK314843.1 Homo sapiens cDNA, FLJ95734 P
AK296628.1 Homo sapiens cDNA FLJ50979 complete cds, moderately similar to Integrin-linked protein kinase (EC PA
AK293474.1 Homo sapiens cDNA FLJ53825 complete cds, highly similar to Integrin-linked protein kinase 1 (EC PA

EST sequences (10 of 620) [Show all sequences]

AA962461.1 Clone IMAGE:1553591 kidney 3' read A
AA969070.1 Clone IMAGE:1580734 mixed 3' read A
AA973280.1 Clone IMAGE:1536931 kidney 3' read A
R14703.1 Clone IMAGE:30066 brain 5' read P
AI037857.1 Clone IMAGE:1664686 skin 3' read PA
AI077857.1 Clone IMAGE:1665504 skin 3' read A
CA976008.1 Clone IMAGE:6202413 nerve 5' read P
AI125341.1 Clone IMAGE:1736984 testis 3' read A
AI219509.1 Clone IMAGE:1845601 mixed 3' read A
AI201729.1 Clone IMAGE:1943985 prostate 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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