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UGID:3093876     UniGene Hs.701991     Homo sapiens (human)   CIITA
Class II, major histocompatibility complex, transactivator (CIITA)

Human protein-coding gene CIITA. Represented by 100 ESTs from 55 cDNA libraries. Corresponds to reference sequence NM_000246.3. [UniGene 3093876 - Hs.701991]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000237.2 CIITA gene product H. sapiens 100.0 1129
NP_031601.1 Ciita gene product M. musculus 77.3 1077
XP_001343072.2 PREDICTED: MHC class II transactivator D. rerio 46.7 244
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_510813.2 PREDICTED: MHC class II transactivator P. troglodytes 99.4 1129
XP_003916579.1 PREDICTED: MHC class II transactivator isoform 1 P. anubis 95.7 1129

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lymph node; mammary gland; lung; connective tissue; brain; blood; mixed; uncharacterized tissue; lymph; intestine; uterus; pancreas; spleen; testis; heart; kidney; stomach; ovary; adipose tissue; bone marrow; trachea; ganglia
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13
UniSTS entry: Chr 16 RH79123 [Map Viewer]
UniSTS entry: Chr 16 STS-U18288
UniSTS entry: Chr 16 SHGC-60649 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000246.3 Homo sapiens class II, major histocompatibility complex, transactivator (CIITA), mRNA P
AY699071.1 Homo sapiens CIITA IV (MHC2TA) mRNA, complete cds P
AY084055.1 Homo sapiens MHC class II transactivator CIITAlo mRNA, complete cds P
AY084054.1 Homo sapiens MHC class II transactivator CIITAmed mRNA, complete cds P
U18303.1 Human clone CIITA-1.23 MHC class II transactivator CIITA mRNA, intronic insert sequence
U18302.1 Human clone CIITA-2.11 MHC class II transactivator CIITA mRNA, intronic insert sequence
U18288.1 Human clone CIITA-10 MHC class II transactivator CIITA mRNA, complete cds P
X74301.1 H.sapiens mRNA for MHC class II transactivator PA
U31931.1 Human class II MHC mutant RJ2.2.5 mRNA, allele CIITA, complete cds P

EST sequences (10 of 100) [Show all sequences]

AI005200.1 Clone IMAGE:1632206 mammary gland 3' read P
BX108506.1 Clone IMAGp998E135766_;_IMAGE:2324724 pancreas P
AI220116.1 Clone IMAGE:1842399 mixed 3' read P
AI221405.1 Clone IMAGE:1842617 mixed 3' read P
AI337800.1 Clone IMAGE:1950429 lung 3' read A
AI439365.1 Clone IMAGE:2134337 lymph node 3' read
AI698228.1 Clone IMAGE:2301459 mixed 3' read P
AI701043.1 Clone IMAGE:2324724 pancreas 3' read P
AW016179.1 Clone IMAGE:2712190 uncharacterized tissue 3' read P
CF142463.1 Clone IMAGE:3101076 lymph node 5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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