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UGID:2727439     UniGene Hs.658121     Homo sapiens (human)   PDE6C
Phosphodiesterase 6C, cGMP-specific, cone, alpha prime (PDE6C)

Human protein-coding gene PDE6C. Represented by 12 ESTs from 5 cDNA libraries. EST representation biased toward connective tissue; soft tissue/muscle tissue tumor; adult. Corresponds to reference sequence NM_006204.3. [UniGene 2727439 - Hs.658121]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006195.3 PDE6C gene product H. sapiens 100.0 857
XP_001148438.1 PREDICTED: cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' P. troglodytes 99.7 857
NP_291092.1 Pde6c gene product M. musculus 88.4 860
NP_957165.1 pde6c gene product D. rerio 71.9 844
NP_650369.3 phosphodiesterase 6, isoform B D. melanogaster 46.5 198
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001092604.1 PREDICTED: cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' M. mulatta 98.7 857
XP_003904063.1 PREDICTED: cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' P. anubis 98.7 857

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: connective tissue [show more like this]
soft tissue/muscle tissue tumor [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; uterus; testis; uncharacterized tissue; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24
UniSTS entry: Chr 10 RH79144
UniSTS entry: Chr 10 SHGC-31657
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

NM_006204.3 Homo sapiens phosphodiesterase 6C, cGMP-specific, cone, alpha prime (PDE6C), mRNA PA
U31973.1 Human phosphodiesterase A' subunit (PDE6C) mRNA, complete cds P

EST sequences (12)

BX955557.1 Clone DKFZp781D2172 uncharacterized tissue 5' read
DB044208.1 Clone TESTI2032120 testis 5' read
DB263764.1 Clone UTERU2022316 uterus 5' read
BG199377.1 connective tissue P
BG203997.1 connective tissue
BG206143.1 connective tissue P
BG213437.1 connective tissue P
BG214519.1 connective tissue P
BG215073.1 connective tissue P
BG216846.1 connective tissue A
BG220856.1 connective tissue A
EL951443.1 eye 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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