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UGID:2724134     UniGene Hs.654816     Homo sapiens (human)   KDM4B
Lysine (K)-specific demethylase 4B (KDM4B)

Human protein-coding gene KDM4B. Represented by 364 ESTs from 158 cDNA libraries. Corresponds to reference sequence NM_015015.2. [UniGene 2724134 - Hs.654816]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055830.1 KDM4B gene product H. sapiens 100.0 1095
XP_001140341.2 PREDICTED: lysine-specific demethylase 4B isoform 1 P. troglodytes 99.7 1129
NP_742144.1 Kdm4b gene product M. musculus 89.2 1085
XP_001339664.2 PREDICTED: lysine-specific demethylase 4A D. rerio 64.3 1034
NP_788344.2 histone demethylase 4B, isoform A D. melanogaster 64.0 483
NP_011096.1 Rph1p S. cerevisiae 52.7 150
NP_496969.2 Protein JMJD-2 C. elegans 51.9 339
XP_955807.2 hypothetical protein NCU03505 N. crassa 51.7 203
XP_001701660.1 jumonji protein C. reinhardtii 51.0 293
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_003914759.1 PREDICTED: lysine-specific demethylase 4B P. anubis 99.0 1095
XP_002801080.1 PREDICTED: lysine-specific demethylase 4B isoform 2 M. mulatta 98.9 1129

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; testis; uncharacterized tissue; eye; ovary; mixed; blood; embryonic tissue; lung; intestine; prostate; kidney; lymph node; uterus; bone marrow; pancreas; adrenal gland; skin; placenta; vascular; pharynx; mouth; liver; muscle; thymus; bladder; cervix; lymph; spleen; stomach; ascites; connective tissue; nerve; bone; parathyroid; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 WI-15786 [Map Viewer]
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 19 RH65659
UniSTS entry: Chr 1 D16S325
UniSTS entry: STS-R38768
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AF052144.1 Homo sapiens clone 24573 and 24786 mRNA sequences A
AB020683.2 Homo sapiens mRNA for KIAA0876 protein, partial cds P
BC046167.1 Homo sapiens, clone IMAGE:4444834, mRNA A
AK126854.1 Homo sapiens cDNA FLJ44906 fis, clone BRAMY3007078, highly similar to JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) P
BC063889.1 Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone IMAGE:30389696), complete cds PA
NM_015015.2 Homo sapiens lysine (K)-specific demethylase 4B (KDM4B), mRNA P
AL133622.1 Homo sapiens mRNA; cDNA DKFZp434P1721 (from clone DKFZp434P1721) PA
AK026040.1 Homo sapiens cDNA: FLJ22387 fis, clone HRC07655 PA
AK090405.1 Homo sapiens mRNA for FLJ00291 protein A
AL831872.1 Homo sapiens mRNA; cDNA DKFZp547A1310 (from clone DKFZp547A1310) A
BC015378.1 Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone IMAGE:4432212), with apparent retained intron A
BC144292.1 Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone MGC:177829 IMAGE:9052812), complete cds P
BC136611.1 Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone MGC:168224 IMAGE:9020601), complete cds P
BC040014.1 Homo sapiens jumonji domain containing 2B, mRNA (cDNA clone IMAGE:5785435), partial cds A

EST sequences (10 of 364) [Show all sequences]

AI014892.1 Clone IMAGE:1622504 embryonic tissue 3' read A
R20034.1 Clone IMAGE:34071 brain 5' read
AI081306.1 Clone IMAGE:1661896 mixed 3' read A
BX113660.1 Clone IMAGp998L11157_;_IMAGE:34071 brain A
AI168823.1 Clone IMAGE:1661387 mixed 3' read A
AI184165.1 Clone IMAGE:1751533 testis 3' read A
R27570.1 Clone IMAGE:134505 placenta 3' read A
R27668.1 Clone IMAGE:134505 placenta 5' read
AI265747.1 Clone IMAGE:1928061 lung 3' read
CB158429.1 Clone L19N779227-1-A10 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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