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UGID:2723722     UniGene Hs.654404     Homo sapiens (human)   HLA-B
Major histocompatibility complex, class I, B (HLA-B)

Human protein-coding gene HLA-B. Represented by 92 ESTs from 64 cDNA libraries. [UniGene 2723722 - Hs.654404]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005505.2 HLA-B gene product H. sapiens 89.2 148
XP_003946493.1 PREDICTED: h-2 class I histocompatibility antigen, D-D alpha chain-like isoform 10 M. musculus 56.5 147
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_003918690.1 PREDICTED: patr class I histocompatibility antigen, A-126 alpha chain-like P. anubis 77.7 148
XP_001115633.1 PREDICTED: HLA class I histocompatibility antigen, Cw-12 alpha chain-like, partial M. mulatta 76.9 129

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; lung; uterus; lymph node; pancreas; pharynx; mammary gland; vascular; bone marrow; ovary; prostate; brain; liver; mixed; amniotic fluid; skin; mouth; stomach; uncharacterized tissue; placenta; blood; spleen; adipose tissue; epididymis; pineal gland; thymus
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 HUM00TB019 [Map Viewer]
UniSTS entry: Chr 6 stD6S1124E.1
UniSTS entry: Chr 6 STS-X55711 [Map Viewer]
UniSTS entry: Chr 6 D6S2071 [Map Viewer]
UniSTS entry: Chr 6 D6S1895 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

J00192.1 human histocompatibility antigen mrna clone phla-1
X07061.1 Human M4-111 mRNA for HLA class I antigen
M64254.1 Human MHC class I HLA-B mRNA, partial cds P
M64258.1 Human MHC class I HLA-B mRNA, partial cds

EST sequences (10 of 92) [Show all sequences]

AI052404.1 Clone IMAGE:1671677 uncharacterized tissue 3' read
R23173.1 Clone IMAGE:131346 placenta 5' read
R23714.1 Clone IMAGE:131779 placenta 5' read
T25952.1 thymus
CD685557.1 pharynx
AW062474.1 intestine
AW195944.1 Clone IMAGE:2681472 pancreas 3' read A
AW361099.1 intestine
AW376423.1 intestine
AW378494.1 mouth

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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