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UGID:2481304     UniGene Hs.650680     Homo sapiens (human)   AIFM2
Apoptosis-inducing factor, mitochondrion-associated, 2 (AIFM2)

Human protein-coding gene AIFM2. Represented by 161 ESTs from 102 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2481304 - Hs.650680]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_116186.1 AIFM2 gene product H. sapiens 100.0 372
XP_003903882.1 PREDICTED: apoptosis-inducing factor 2 isoform 1 P. anubis 99.7 372
XP_001170716.1 PREDICTED: apoptosis-inducing factor 2 isoform 6 P. troglodytes 99.7 372
NP_835159.1 Aifm2 gene product M. musculus 93.0 372
NP_001091397.1 apoptosis-inducing factor 2 X. laevis 66.5 373
NP_001186939.1 LOC557507 gene product D. rerio 60.0 372
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001108816.2 PREDICTED: apoptosis-inducing factor 2-like isoform 3 M. mulatta 99.0 392
NP_001132955.1 apoptosis-inducing factor, mitochondrion-associated 2 R. norvegicus 93.3 372

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; uncharacterized tissue; adipose tissue; intestine; kidney; prostate; bone marrow; brain; embryonic tissue; liver; uterus; spinal cord; mouth; ovary; skin; pituitary gland; heart; testis; mammary gland; mixed; cervix; placenta; thyroid; stomach; connective tissue; spleen; bone; eye; thymus; pancreas; salivary gland; muscle
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q22.1
UniSTS entry: Chr 10 D10S2375
UniSTS entry: Chr 10 RH99102
UniSTS entry: Chr 10 STS-T93317 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BC006121.1 Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 2, mRNA (cDNA clone MGC:13000 IMAGE:3506309), complete cds PA
AK027403.1 Homo sapiens cDNA FLJ14497 fis, clone NT2RM1000039 P
NM_032797.5 Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 2 (AIFM2), transcript variant 2, mRNA PA
AF506757.1 Homo sapiens AMID protein mRNA, complete cds PA
BC023601.2 Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 2, mRNA (cDNA clone MGC:23230 IMAGE:4548458), complete cds PA
NM_001198696.1 Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 2 (AIFM2), transcript variant 1, mRNA PA

EST sequences (10 of 161) [Show all sequences]

AI056644.1 Clone IMAGE:1675725 mixed 3' read A
AI143457.1 Clone IMAGE:1690690 mixed 3' read P
AI216265.1 Clone IMAGE:1884109 lung 3' read A
AI261420.1 Clone IMAGE:1868367 kidney 3' read A
CB164713.1 Clone L17N670205n1-43-F08 liver 5' read A
AI270335.1 Clone IMAGE:1978918 stomach 3' read A
AI273631.1 Clone IMAGE:1876321 mixed 3' read A
AI340666.1 Clone IMAGE:2056059 bone marrow 3' read
AA724584.1 Clone IMAGE:1327298 mixed 3' read A
AI393971.1 Clone IMAGE:2107952 uncharacterized tissue 3' read PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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