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UGID:2477742     UniGene Hs.647118     Homo sapiens (human)   ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8)

Human protein-coding gene ABCB8. Represented by 500 ESTs from 218 cDNA libraries. Corresponds to reference sequence NM_007188.3. [UniGene 2477742 - Hs.647118]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_009119.2 ABCB8 gene product H. sapiens 100.0 717
XP_519524.3 PREDICTED: ATP-binding cassette sub-family B member 8, mitochondrial P. troglodytes 99.9 717
NP_083296.2 Abcb8 gene product M. musculus 89.5 716
NP_001017544.1 abcb8 gene product D. rerio 72.5 676
NP_198720.2 ABC transporter B family member 27 A. thaliana 60.3 320
NP_572810.1 CG1824 D. melanogaster 58.9 601
NP_001081394.1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 X. laevis 58.2 888
NP_490828.3 Protein HAF-6 C. elegans 58.2 580
XP_001692124.1 hypothetical protein CHLREDRAFT_100930 C. reinhardtii 54.6 226
XP_965328.2 hypothetical protein NCU03228 N. crassa 49.8 259
NP_014030.1 ATP-binding cassette Fe/S cluster precursor transporter ATM1 S. cerevisiae 45.5 224
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_001101229.1 PREDICTED: ATP-binding cassette sub-family B member 8, mitochondrial isoform 2 M. mulatta 98.0 734
XP_003896912.1 PREDICTED: ATP-binding cassette sub-family B member 8, mitochondrial isoform 3 P. anubis 97.7 734

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; skin; placenta; kidney; adipose tissue; stomach; lung; thyroid; lymph node; esophagus; cervix; spleen; mouth; pharynx; adrenal gland; thymus; umbilical cord; mixed; intestine; prostate; liver; heart; eye; mammary gland; uterus; embryonic tissue; bone marrow; connective tissue; blood; ascites; vascular; bone; muscle; trachea; salivary gland; nerve; pancreas; ovary; tonsil; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q36
UniSTS entry: Chr 7 MARC_15633-15634:1017248647:1
UniSTS entry: Chr 7 SHGC-34711
UniSTS entry: SHGC-57908
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AF047690.1 Homo sapiens ATP-binding cassette protein M-ABC1 mRNA, nuclear gene encoding mitochondrial protein, complete cds P
NM_007188.3 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8), nuclear gene encoding mitochondrial protein, mRNA PA
AK002018.1 Homo sapiens cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to ATP-DEPENDENT PERMEASE MDL1 P
AK222911.1 Homo sapiens mRNA for ATP-binding cassette, sub-family B, member 8 variant, clone: HRC04144 P
AK024401.1 Homo sapiens cDNA FLJ14339 fis, clone SKNMC1000013, highly similar to ATP-binding cassette sub-family B member 8,mitochondrial precursor P
BC141836.1 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8, mRNA (cDNA clone MGC:165100 IMAGE:40148945), complete cds PA
BC141814.1 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8, mRNA (cDNA clone MGC:164861 IMAGE:40147981), complete cds PA
BC151235.1 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8, mRNA (cDNA clone MGC:167097 IMAGE:8860430), complete cds PA
AK310796.1 Homo sapiens cDNA, FLJ17838 P
AK314721.1 Homo sapiens cDNA, FLJ95580, highly similar to Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 8 (ABCB8), nuclear gene encoding mitochondrial protein, mRNA P
AK094636.1 Homo sapiens cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to Homo sapiens ATP-binding cassette protein M-ABC1 mRNA P
AK094005.1 Homo sapiens cDNA FLJ36686 fis, clone UTERU2008027, highly similar to ATP-binding cassette sub-family B member 8, mitochondrial precursor P
AK294344.1 Homo sapiens cDNA FLJ56066 complete cds, highly similar to ATP-binding cassette sub-family B member 8, mitochondrial precursor P
U66688.1 Homo sapiens clone EST328128 mRNA sequence P
AL117497.1 Homo sapiens mRNA; cDNA DKFZp434C1435 (from clone DKFZp434C1435) A
AF086382.1 Homo sapiens full length insert cDNA clone ZD70D07 A

EST sequences (10 of 500) [Show all sequences]

AA974073.1 Clone IMAGE:1586199 uncharacterized tissue 3' read
AI083583.1 Clone IMAGE:1660779 mixed 3' read
CB045359.1 Clone IMAGE:3218534 intestine 3' read A
CB045360.1 Clone IMAGE:3218534 intestine 5' read P
CB046770.1 Clone IMAGE:3253035 kidney 3' read P
CB046771.1 Clone IMAGE:3253035 kidney 5' read P
BX110915.1 Clone IMAGp998F02298_;_IMAGE:167041 brain P
BX107751.1 Clone IMAGp998F14791_;_IMAGE:345997 heart A
AI168486.1 Clone IMAGE:1565827 mixed 3' read A
CB111887.1 Clone L5HLK1-22-H01 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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