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UGID:2477702     UniGene Hs.647078     Homo sapiens (human)   CDK5
Cyclin-dependent kinase 5 (CDK5)

Human protein-coding gene CDK5. Represented by 168 ESTs from 96 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2477702 - Hs.647078]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031694.1 Cdk5 gene product M. musculus 100.0 291
XP_001363728.1 PREDICTED: cyclin-dependent kinase 5-like M. domestica 100.0 291
XP_001102523.1 PREDICTED: cell division protein kinase 5 isoform 1 M. mulatta 100.0 291
XP_003896922.1 PREDICTED: cyclin-dependent kinase 5 isoform 1 P. anubis 100.0 291
XP_519523.2 PREDICTED: cyclin-dependent kinase 5 isoform 2 P. troglodytes 100.0 291
NP_004926.1 CDK5 gene product H. sapiens 100.0 291
XP_001504704.1 PREDICTED: cyclin-dependent kinase 5-like isoform 1 E. caballus 100.0 291
NP_001038086.2 cyclin-dependent kinase 5 S. scrofa 100.0 291
NP_776442.1 CDK5 gene product B. taurus 100.0 291
NP_001129403.1 CDK5 gene product O. aries 100.0 291
XP_002715121.1 PREDICTED: cyclin-dependent kinase 5 isoform 1 O. cuniculus 100.0 291
NP_543161.1 Cdk5 gene product R. norvegicus 99.7 291
NP_001084086.1 cyclin-dependent kinase 5 X. laevis 99.0 291
NP_571794.1 cdk5 gene product D. rerio 98.6 291
NP_477080.1 Cyclin-dependent kinase 5 D. melanogaster 87.2 288
NP_499783.1 Protein CDK-5 C. elegans 81.2 288
XP_958274.1 negative regulator of the PHO system N. crassa 65.3 291
NP_015294.1 Pho85p S. cerevisiae 63.9 299
XP_001698637.1 cyclin dependent protein kinase C. reinhardtii 63.7 303
NP_566911.1 cyclin-dependent kinase A-1 A. thaliana 61.2 289
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_532760.3 PREDICTED: cyclin-dependent kinase 5 C. lupus familiaris 99.0 316
XP_003975303.1 PREDICTED: cyclin-dependent kinase 5-like isoform 1 T. rubripes 99.0 291

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; kidney; pancreas; ovary; heart; bone marrow; adrenal gland; skin; pharynx; eye; prostate; lung; embryonic tissue; testis; liver; uterus; mammary gland; thyroid; ascites; connective tissue; salivary gland; bone; muscle; tonsil; blood; intestine
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q36
UniSTS entry: Chr 7 SGC30025 [Map Viewer]
UniSTS entry: Chr 19 SHGC-33210 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BT006680.1 Homo sapiens cyclin-dependent kinase 5 mRNA, complete cds P
NM_004935.3 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 1, mRNA PA
CR457041.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0318D for gene CDK5, cyclin-dependent kinase 5; complete cds, incl. stopcodon P
AY927560.1 Homo sapiens mRNA sequence P
AK026533.1 Homo sapiens cDNA: FLJ22880 fis, clone KAT03552, highly similar to HSSTHPKE Homo sapiens mRNA PSSALRE for serine/threonine protein kinase PA
BC005115.1 Homo sapiens cyclin-dependent kinase 5, mRNA (cDNA clone MGC:1469 IMAGE:3537202), complete cds PA
DQ411039.1 Homo sapiens protein kinase CDK5 splicing variant mRNA, complete cds, alternatively spliced P
AY049778.1 Homo sapiens cyclin-dependent kinase 5 (CDK5) mRNA, complete cds P
NM_001164410.1 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 2, mRNA PA
X66364.1 H.sapiens mRNA PSSALRE for serine/threonine protein kinase P
L04658.1 Homo sapiens gene sequence PA

EST sequences (10 of 168) [Show all sequences]

AA902452.1 Clone IMAGE:1519327 uncharacterized tissue 3' read P
AI016846.1 Clone IMAGE:1627468 mixed 3' read P
AI039961.1 Clone IMAGE:1659701 embryonic tissue 3' read
AI124023.1 Clone IMAGE:1691490 heart 3' read PA
CB054785.1 Clone IMAGE:3291627 brain 5' read P
AI086997.1 Clone IMAGE:1680506 skin 3' read PA
BX112764.1 Clone IMAGp998C121824_;_IMAGE:742595 testis P
CB114175.1 Clone L3SNU475s1-8-D12 liver 5' read P
CB144453.1 Clone L11SNU354s1-8-C02 liver 5' read P
CB142671.1 Clone L11SNU354s1-12-F06 liver 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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