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UGID:2224092     UniGene Hs.642874     Homo sapiens (human)   RAB8A
RAB8A, member RAS oncogene family (RAB8A)

Human protein-coding gene RAB8A. Represented by 671 ESTs from 295 cDNA libraries. Corresponds to reference sequence NM_005370.4. [UniGene 2224092 - Hs.642874]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_075615.2 Rab8a gene product M. musculus 100.0 206
NP_446450.2 Rab8a gene product R. norvegicus 100.0 206
XP_003915146.1 PREDICTED: ras-related protein Rab-8A isoform 2 P. anubis 100.0 206
NP_001229300.1 RAB8A gene product P. troglodytes 100.0 206
NP_005361.2 RAB8A gene product H. sapiens 100.0 206
NP_001003152.1 RAB8A gene product C. lupus familiaris 100.0 206
XP_001914834.1 PREDICTED: ras-related protein Rab-8A-like E. caballus 100.0 206
NP_001230731.1 RAB8A gene product S. scrofa 100.0 206
NP_001098951.1 RAB8A gene product B. taurus 100.0 206
NP_001155332.1 RAB8A gene product O. aries 100.0 206
XP_001368638.2 PREDICTED: ras-related protein Rab-8A-like M. domestica 99.5 206
NP_001083031.1 rab8a gene product D. rerio 97.6 206
NP_001087181.1 RAB8B, member RAS oncogene family X. laevis 93.2 206
NP_524172.1 Rab8, isoform A D. melanogaster 91.3 206
NP_491199.2 Protein RAB-8 C. elegans 87.7 210
NP_195972.1 RAB GTPase-8C A. thaliana 78.1 214
XP_962242.1 GTP-binding protein SAS1 N. crassa 77.7 202
XP_001703081.1 small rab-related GTPase C. reinhardtii 67.6 213
NP_116650.1 Sec4p S. cerevisiae 66.3 207
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_002934841.1 PREDICTED: ras-related protein Rab-8A X. tropicalis 98.5 206
XP_003974173.1 PREDICTED: ras-related protein Rab-8A-like T. rubripes 97.6 205

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; testis; skin; uncharacterized tissue; placenta; intestine; prostate; blood; embryonic tissue; thyroid; uterus; bladder; liver; mixed; eye; kidney; cervix; bone; pancreas; connective tissue; lymph; muscle; stomach; mammary gland; vascular; ovary; spleen; esophagus; bone marrow; pituitary gland; thymus; lymph node; mouth; pharynx; adrenal gland; tonsil; ascites; salivary gland; trachea; nerve; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.1
UniSTS entry: Chr 19 SHGC-36999
UniSTS entry: Chr 19 RH78768 [Map Viewer]
UniSTS entry: Chr 19 RH103628
UniSTS entry: Chr 19 STS-H77454 [Map Viewer]
UniSTS entry: Chr 19 RAB8A_8465
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BT007184.1 Homo sapiens mel transforming oncogene (derived from cell line NK14)- RAB8 homolog mRNA, complete cds P
NM_005370.4 Homo sapiens RAB8A, member RAS oncogene family (RAB8A), mRNA PA
CR536583.1 Homo sapiens full open reading frame cDNA clone RZPDo834C0322D for gene RAB8A, RAB8A, member RAS oncogene family; complete cds, incl. stopcodon P
CR542274.1 Homo sapiens full open reading frame cDNA clone RZPDo834F0726D for gene RAB8A, RAB8A, member RAS oncogene family; complete cds, without stopcodon P
AY927516.1 Homo sapiens mRNA sequence
AB209767.1 Homo sapiens mRNA for mel transforming oncogene variant protein P
AK025165.1 Homo sapiens cDNA: FLJ21512 fis, clone COL05769 PA
BC002977.1 Homo sapiens RAB8A, member RAS oncogene family, mRNA (cDNA clone MGC:2196 IMAGE:3547214), complete cds PA
AF498943.1 Homo sapiens small GTP binding protein RAB8 (RAB8) mRNA, complete cds P
AK095221.1 Homo sapiens cDNA FLJ37902 fis, clone CD34C3000494
AK293676.1 Homo sapiens cDNA FLJ53028 complete cds, highly similar to Ras-related protein Rab-8A P
X56741.1 H.sapiens mRNA for rab8 gene P

EST sequences (10 of 671) [Show all sequences]

AA995825.1 Clone IMAGE:1611934 uncharacterized tissue 3' read A
AI049970.1 Clone IMAGE:1700971 kidney 3' read A
AI082781.1 Clone IMAGE:1662029 mixed 3' read P
AI091663.1 Clone IMAGE:1566685 mixed 3' read A
AI091860.1 Clone IMAGE:1690985 mixed 3' read A
AI125741.1 Clone IMAGE:1736826 testis 3' read A
AI126505.1 Clone IMAGE:1713156 uterus 3' read A
AI129748.1 Clone IMAGE:1712115 uterus 3' read A
AI138457.1 Clone IMAGE:1713318 placenta 3' read A
AI150894.1 Clone IMAGE:1703365 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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