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UGID:2142244     UniGene Hs.635350     Homo sapiens (human)   SPON2
Spondin 2, extracellular matrix protein (SPON2)

Human protein-coding gene SPON2. Represented by 570 ESTs from 160 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2142244 - Hs.635350]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001121797.1 SPON2 gene product H. sapiens 100.0 330
XP_001141954.1 PREDICTED: spondin-2 isoform 4 P. troglodytes 99.7 330
NP_598664.3 Spon2 gene product M. musculus 89.7 329
NP_001087070.1 spondin 2, extracellular matrix protein X. laevis 71.2 301
NP_571083.4 spondin-2 precursor D. rerio 68.5 313
NP_725407.1 M-spondin D. melanogaster 52.7 131
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_003890964.1 PREDICTED: spondin-2 isoform 1 P. anubis 99.1 330
XP_001092523.1 PREDICTED: spondin-2 M. mulatta 97.6 330

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: prostate; brain; placenta; uterus; mixed; uncharacterized tissue; kidney; intestine; lung; pancreas; skin; stomach; embryonic tissue; umbilical cord; cervix; blood; mammary gland; spleen; eye; ascites; salivary gland; testis; thymus; larynx; nerve; muscle; ovary; esophagus; connective tissue; heart; adrenal gland; trachea; liver; bone; bladder; bone marrow
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.3
UniSTS entry: Chr 4 WI-22263 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK130164.1 Homo sapiens cDNA FLJ26654 fis, clone MPE06871, highly similar to Homo sapiens spondin 2, extracellular matrix protein (SPON2) P
AK124606.1 Homo sapiens cDNA FLJ42615 fis, clone BRACE3014231
AY358948.1 Homo sapiens clone DNA53971 SPON2 (UNQ435) mRNA, complete cds PA
NM_012445.3 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 1, mRNA PA
AB027466.1 Homo sapiens SPON2 mRNA for spondin 2, complete cds P
BC002707.2 Homo sapiens spondin 2, extracellular matrix protein, mRNA (cDNA clone MGC:3472 IMAGE:3630467), complete cds PA
NM_001128325.2 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 2, mRNA PA
AK074770.1 Homo sapiens cDNA FLJ90289 fis, clone NT2RP1001004, highly similar to Spondin 2, extracellular matrix protein P
AK074618.1 Homo sapiens cDNA FLJ90137 fis, clone HEMBB1000881, weakly similar to Danio rerio mRNA for MINDIN2 P
BC036341.1 Homo sapiens spondin 2, extracellular matrix protein, mRNA (cDNA clone MGC:35367 IMAGE:5183118), complete cds PA
NM_001199021.1 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 3, mRNA PA

EST sequences (10 of 570) [Show all sequences]

AA864573.1 Clone IMAGE:1459408 kidney 3' read A
AI122890.1 Clone IMAGE:1695015 uterus 3' read
AI123203.1 Clone IMAGE:1566419 mixed 3' read A
AI129064.1 Clone IMAGE:1663569 skin 3' read A
CB048860.1 Clone IMAGE:3270934 prostate 3' read A
CB048861.1 Clone IMAGE:3270934 prostate 5' read A
CB050279.1 Clone IMAGE:3271647 prostate 3' read A
CB050515.1 Clone IMAGE:3271957 prostate 5' read
AI084783.1 Clone IMAGE:1681617 skin 3' read A
BX100033.1 Clone IMAGp998I121775_;_IMAGE:723923 ovary

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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