NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:2142244     UniGene Hs.635350     Homo sapiens (human)   SPON2
Spondin 2, extracellular matrix protein (SPON2)

Human protein-coding gene SPON2. Represented by 570 ESTs from 160 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2142244 - Hs.635350]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001121797.1 SPON2 gene product H. sapiens 100.0 330
XP_001141954.1 PREDICTED: spondin-2 isoform 4 P. troglodytes 99.7 330
NP_598664.3 Spon2 gene product M. musculus 89.7 329
NP_001087070.1 spondin 2, extracellular matrix protein X. laevis 71.2 301
NP_571083.4 spondin-2 precursor D. rerio 68.5 313
NP_725407.1 M-spondin D. melanogaster 52.7 131
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_003890964.1 PREDICTED: spondin-2 isoform 1 P. anubis 99.1 330
XP_001092523.1 PREDICTED: spondin-2 M. mulatta 97.6 330

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: prostate; brain; placenta; uterus; mixed; uncharacterized tissue; kidney; intestine; lung; pancreas; skin; stomach; embryonic tissue; umbilical cord; cervix; blood; mammary gland; spleen; eye; ascites; salivary gland; testis; thymus; larynx; nerve; muscle; ovary; esophagus; connective tissue; heart; adrenal gland; trachea; liver; bone; bladder; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.3
UniSTS entry: Chr 4 WI-22263 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK130164.1 Homo sapiens cDNA FLJ26654 fis, clone MPE06871, highly similar to Homo sapiens spondin 2, extracellular matrix protein (SPON2) P
AK124606.1 Homo sapiens cDNA FLJ42615 fis, clone BRACE3014231
AY358948.1 Homo sapiens clone DNA53971 SPON2 (UNQ435) mRNA, complete cds PA
NM_012445.3 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 1, mRNA PA
AB027466.1 Homo sapiens SPON2 mRNA for spondin 2, complete cds P
BC002707.2 Homo sapiens spondin 2, extracellular matrix protein, mRNA (cDNA clone MGC:3472 IMAGE:3630467), complete cds PA
NM_001128325.2 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 2, mRNA PA
AK074770.1 Homo sapiens cDNA FLJ90289 fis, clone NT2RP1001004, highly similar to Spondin 2, extracellular matrix protein P
AK074618.1 Homo sapiens cDNA FLJ90137 fis, clone HEMBB1000881, weakly similar to Danio rerio mRNA for MINDIN2 P
BC036341.1 Homo sapiens spondin 2, extracellular matrix protein, mRNA (cDNA clone MGC:35367 IMAGE:5183118), complete cds PA
NM_001199021.1 Homo sapiens spondin 2, extracellular matrix protein (SPON2), transcript variant 3, mRNA PA

EST sequences (10 of 570) [Show all sequences]

AA864573.1 Clone IMAGE:1459408 kidney 3' read A
AI122890.1 Clone IMAGE:1695015 uterus 3' read
AI123203.1 Clone IMAGE:1566419 mixed 3' read A
AI129064.1 Clone IMAGE:1663569 skin 3' read A
CB048860.1 Clone IMAGE:3270934 prostate 3' read A
CB048861.1 Clone IMAGE:3270934 prostate 5' read A
CB050279.1 Clone IMAGE:3271647 prostate 3' read A
CB050515.1 Clone IMAGE:3271957 prostate 5' read
AI084783.1 Clone IMAGE:1681617 skin 3' read A
BX100033.1 Clone IMAGp998I121775_;_IMAGE:723923 ovary


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help