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UGID:2140403     UniGene Hs.633509     Homo sapiens (human)   RAD50
RAD50 homolog (S. cerevisiae) (RAD50)

Human protein-coding gene RAD50. Represented by 331 ESTs from 174 cDNA libraries. Corresponds to reference sequence NM_005732.3. [UniGene 2140403 - Hs.633509]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001163412.1 PREDICTED: DNA repair protein RAD50 isoform 1 P. troglodytes 100.0 1311
NP_005723.2 RAD50 gene product H. sapiens 100.0 1311
XP_001099384.2 PREDICTED: DNA repair protein RAD50-like M. mulatta 99.8 1310
NP_001162505.1 DNA repair protein RAD50 P. anubis 99.8 1310
NP_033038.2 Rad50 gene product M. musculus 96.1 1311
NP_001154855.1 RAD50 homolog X. laevis 80.6 1311
XP_696859.4 PREDICTED: DNA repair protein RAD50 D. rerio 78.4 1311
XP_001693249.1 DNA repair protein C. reinhardtii 63.1 233
NP_565733.1 DNA repair protein RAD50 A. thaliana 59.9 1309
NP_014149.1 Rad50p S. cerevisiae 57.8 1302
XP_963818.1 hypothetical protein NCU00901 N. crassa 56.0 1312
NP_726199.3 rad50, isoform D D. melanogaster 52.7 1304
NP_506070.1 Protein RAD-50, isoform a C. elegans 45.8 190
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_531901.2 PREDICTED: DNA repair protein RAD50 C. lupus familiaris 98.2 1311
NP_001164819.1 DNA repair protein RAD50 O. cuniculus 98.2 1311

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; testis; heart; thymus; lymph; bone marrow; skin; mouth; embryonic tissue; mammary gland; mixed; uncharacterized tissue; placenta; liver; stomach; muscle; adipose tissue; uterus; adrenal gland; pancreas; intestine; bone; ear; lung; ovary; lymph node; thyroid; kidney; connective tissue; salivary gland; blood; prostate; larynx; trachea; ascites; nerve; ganglia; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31
UniSTS entry: Chr 5 REN70734
UniSTS entry: Chr 5 REN70951
UniSTS entry: Chr 5 REN71093
UniSTS entry: Chr 5 ECD23431
UniSTS entry: Chr 5 REN71090
UniSTS entry: Chr 5 ECD17518
UniSTS entry: Chr 5 stSG601375
UniSTS entry: Chr 5 REN71091
UniSTS entry: Chr 5 REN71096
UniSTS entry: Chr 5 REN71094
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_005732.3 Homo sapiens RAD50 homolog (S. cerevisiae) (RAD50), mRNA P
BC062603.1 Homo sapiens RAD50 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:5493315), partial cds PA
BC073850.1 Homo sapiens RAD50 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:4385515), partial cds PA
AF057299.1 Homo sapiens RAD50-2 protein (RAD50) mRNA, alternatively spliced, complete cds PA
AF057300.1 Homo sapiens truncated RAD50 protein (RAD50) mRNA, complete cds PA
BC108282.1 Homo sapiens RAD50 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:3855371), partial cds PA
DQ655928.2 Homo sapiens clone UGL7g07, mRNA sequence P
BC140005.1 Homo sapiens RAD50 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:8860357), partial cds PA
AK290597.1 Homo sapiens cDNA FLJ75532 partial cds, highly similar to Homo sapiens RAD50 homolog (S. cerevisiae) (RAD50), transcript variant 1, mRNA PA
AK307439.1 Homo sapiens cDNA, FLJ97387 P
U63139.1 Homo sapiens Rad50 (Rad50) mRNA, complete cds PA
BC136436.1 Homo sapiens RAD50 homolog (S. cerevisiae), mRNA (cDNA clone MGC:168048 IMAGE:9020425), complete cds P

EST sequences (10 of 331) [Show all sequences]

AA908963.1 Clone IMAGE:1523103 mixed 3' read
AA927430.1 Clone IMAGE:1552522 uncharacterized tissue 3' read P
AI041744.1 Clone IMAGE:1660419 mixed 3' read A
AI080253.1 Clone IMAGE:1678516 mixed 3' read PA
AI188920.1 Clone IMAGE:1724012 placenta 3' read
AI189811.1 Clone IMAGE:1724157 placenta 3' read
CB105665.1 Clone L2HLK1-1-C03 liver 5' read PA
CB111439.1 Clone L5HLK1-11-E11 liver 5' read
CB122498.1 Clone L8SCK0-31-F11 liver 5' read
CB118735.1 Clone L8SCK0-21-D10 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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