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UGID:2139601     UniGene Hs.632707     Homo sapiens (human)   MARS
Methionyl-tRNA synthetase (MARS)

Human protein-coding gene MARS. Represented by 1651 ESTs from 416 cDNA libraries. Corresponds to reference sequence NM_004990.3. [UniGene 2139601 - Hs.632707]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004981.2 MARS gene product H. sapiens 100.0 899
XP_509164.2 PREDICTED: methionine--tRNA ligase, cytoplasmic P. troglodytes 99.9 899
NP_001003913.1 methionine--tRNA ligase, cytoplasmic isoform 2 M. musculus 92.8 901
NP_001079984.1 methionine--tRNA ligase, cytoplasmic X. laevis 80.4 904
NP_956370.1 mars gene product D. rerio 77.7 921
NP_001255572.1 Protein MARS-1, isoform b C. elegans 69.8 616
NP_193114.1 methionyl-tRNA synthetase A. thaliana 66.8 584
NP_011780.3 methionine--tRNA ligase MES1 S. cerevisiae 66.6 569
NP_611382.1 CG15100 D. melanogaster 64.3 876
XP_001701951.1 predicted protein C. reinhardtii 62.1 652
XP_964638.1 hypothetical protein NCU07451 N. crassa 59.1 661
Other hits (2 of 53) [Show all]SpeciesId(%)Len(aa)
XP_001116063.1 PREDICTED: methionyl-tRNA synthetase, cytoplasmic-like isoform 4 M. mulatta 99.4 899
XP_003906701.1 PREDICTED: LOW QUALITY PROTEIN: methionine--tRNA ligase, cytoplasmic P. anubis 99.4 898

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; muscle; testis; uncharacterized tissue; lung; intestine; embryonic tissue; mouth; connective tissue; uterus; skin; thymus; placenta; stomach; eye; liver; kidney; prostate; ascites; mixed; lymph; blood; pancreas; bone marrow; cervix; mammary gland; vascular; trachea; bone; spleen; heart; tonsil; thyroid; parathyroid; lymph node; larynx; bladder; ovary; umbilical cord; pharynx; esophagus; nerve; adrenal gland; salivary gland; ganglia; adipose tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13
UniSTS entry: Chr 12 RH17412 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BT007338.1 Homo sapiens methionine-tRNA synthetase mRNA, complete cds P
NM_004990.3 Homo sapiens methionyl-tRNA synthetase (MARS), mRNA PA
BC065187.1 Homo sapiens methionine-tRNA synthetase, mRNA (cDNA clone IMAGE:5021529), partial cds PA
D84224.1 Homo sapiens mRNA for methionyl tRNA synthetase, complete cds P
AK222767.1 Homo sapiens mRNA for methionine-tRNA synthetase variant, clone: HEP00371 P
BC002384.2 Homo sapiens methionyl-tRNA synthetase, mRNA (cDNA clone MGC:8646 IMAGE:2961615), complete cds PA
BC006328.2 Homo sapiens methionyl-tRNA synthetase, mRNA (cDNA clone MGC:12889 IMAGE:4139330), complete cds PA
BC011849.2 Homo sapiens methionyl-tRNA synthetase, mRNA (cDNA clone MGC:20313 IMAGE:4135154), complete cds PA
BC011639.2 Homo sapiens methionyl-tRNA synthetase, mRNA (cDNA clone MGC:12828 IMAGE:4120680), complete cds PA
BC015011.1 Homo sapiens methionyl-tRNA synthetase, mRNA (cDNA clone IMAGE:4864644), partial cds PA
AK290857.1 Homo sapiens cDNA FLJ76789 complete cds, highly similar to Homo sapiens methionine-tRNA synthetase (MARS), mRNA PA
Z49216.1 H.sapiens mitoxantrone-resistance associated mRNA PA
AK303349.1 Homo sapiens cDNA FLJ55046 complete cds, highly similar to Methionyl-tRNA synthetase (EC P
X94754.1 H.sapiens mRNA for yeast methionyl-tRNA synthetase homologue P

EST sequences (10 of 1651) [Show all sequences]

AA977362.1 Clone IMAGE:1588950 kidney 3' read PA
AI003458.1 Clone IMAGE:1414883 spleen 3' read A
R17591.1 Clone IMAGE:32132 brain 5' read P
AI034100.1 Clone IMAGE:1646285 parathyroid 3' read P
AI034103.1 Clone IMAGE:1646293 parathyroid 3' read PA
R21274.1 Clone IMAGE:35559 brain 5' read P
AI091754.1 Clone IMAGE:1694095 heart 3' read
AI123477.1 Clone IMAGE:1640711 testis 3' read PA
AI129052.1 Clone IMAGE:1663562 skin 3' read A
AI150434.1 Clone IMAGE:1752070 testis 3' read PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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