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UGID:2139449     UniGene Hs.632555     Homo sapiens (human)   AP1S3
Adaptor-related protein complex 1, sigma 3 subunit (AP1S3)

Human protein-coding gene AP1S3. Represented by 70 ESTs from 51 cDNA libraries. Corresponds to reference sequence NM_001039569.1. [UniGene 2139449 - Hs.632555]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001098858.2 PREDICTED: AP-1 complex subunit sigma-3-like M. mulatta 100.0 153
XP_003908058.1 PREDICTED: AP-1 complex subunit sigma-3 P. anubis 100.0 153
XP_516121.2 PREDICTED: AP-1 complex subunit sigma-3 P. troglodytes 100.0 153
NP_001034658.1 AP1S3 gene product H. sapiens 100.0 153
NP_898848.1 Ap1s3 gene product M. musculus 97.4 153
NP_001180334.1 adaptor-related protein complex 1, sigma 3 subunit X. laevis 88.3 153
NP_001004635.1 ap1s3b gene product D. rerio 80.5 153
NP_001247273.1 AP-1sigma, isoform B D. melanogaster 79.5 151
NP_504559.1 Protein APS-1 C. elegans 75.2 149
NP_565415.1 AP-1 complex subunit sigma-1 A. thaliana 62.6 147
XP_001694476.1 Sigma1-Adaptin C. reinhardtii 60.8 157
XP_962659.1 AP-2 complex subunit sigma N. crassa 48.2 142
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
NP_001096766.1 AP1S3 gene product B. taurus 98.0 153
XP_004005490.1 PREDICTED: AP-1 complex subunit sigma-3 O. aries 97.5 156

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; mammary gland; thyroid; lymph node; embryonic tissue; skin; cervix; brain; prostate; mixed; placenta; kidney; uncharacterized tissue; liver; vascular; lymph; bone; tonsil; bladder; blood; stomach; muscle; eye; lung
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q36.1
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 1 D1S1423
UniSTS entry: Chr 1 D8S2279
UniSTS entry: Chr 1 L17709
UniSTS entry: Chr 1 L17971
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 GDB:434012
UniSTS entry: Chr 1 D15S1477
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AK025338.1 Homo sapiens cDNA: FLJ21685 fis, clone COL09372 A
NM_001039569.1 Homo sapiens adaptor-related protein complex 1, sigma 3 subunit (AP1S3), mRNA P
AF393369.1 Homo sapiens sigma 1C adaptin (AP1S3) mRNA, complete cds P
BC009606.1 Homo sapiens adaptor-related protein complex 1, sigma 3 subunit, mRNA (cDNA clone MGC:14759 IMAGE:4284350), complete cds PA
AK299026.1 Homo sapiens cDNA FLJ56679 complete cds, highly similar to Adapter-relatedprotein complex 1 sigma- 1C subunit P

EST sequences (10 of 70) [Show all sequences]

CB144134.1 Clone L16HLK3-7-A11 liver 5' read
CB113572.1 Clone L6ChoCK0-22-F08 liver 5' read P
AI474433.1 Clone IMAGE:2118831 prostate 3' read A
AI478514.1 Clone IMAGE:2161806 kidney 3' read A
AI826972.1 Clone IMAGE:2419286 prostate 3' read
CB994892.1 Clone IMAGE:30338907 placenta 5' read P
CB998235.1 Clone IMAGE:30348527 placenta 5' read P
CB998243.1 Clone IMAGE:30348479 placenta 5' read P
AI972826.1 Clone IMAGE:2490513 prostate 3' read A
AW044128.1 Clone IMAGE:2553883 mixed 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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