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UGID:2139448     UniGene Hs.632554     Homo sapiens (human)   SF3B1
Splicing factor 3b, subunit 1, 155kDa (SF3B1)

Human protein-coding gene SF3B1. Represented by 865 ESTs from 362 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2139448 - Hs.632554]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_112456.2 splicing factor 3B subunit 1 M. musculus 100.0 1303
NP_445878.1 splicing factor 3b, subunit 1 R. norvegicus 100.0 1303
XP_001086317.2 PREDICTED: splicing factor 3B subunit 1 M. mulatta 100.0 1303
XP_003907811.1 PREDICTED: splicing factor 3B subunit 1 P. anubis 100.0 1303
XP_516006.3 PREDICTED: splicing factor 3B subunit 1 isoform 2 P. troglodytes 100.0 1303
NP_036565.2 SF3B1 gene product H. sapiens 100.0 1303
XP_545578.2 PREDICTED: splicing factor 3B subunit 1 isoform 1 C. lupus familiaris 100.0 1303
XP_001500218.2 PREDICTED: splicing factor 3B subunit 1 isoform 1 E. caballus 100.0 1303
XP_001928829.1 PREDICTED: splicing factor 3B subunit 1 isoform 1 S. scrofa 100.0 1303
NP_001179923.1 splicing factor 3B subunit 1 B. taurus 100.0 1303
XP_004004838.1 PREDICTED: splicing factor 3B subunit 1 isoform 1 O. aries 100.0 1303
XP_001369944.1 PREDICTED: splicing factor 3B subunit 1 M. domestica 99.8 1302
XP_421912.3 PREDICTED: splicing factor 3B subunit 1 G. gallus 99.8 1300
XP_002192675.1 PREDICTED: splicing factor 3B subunit 1 T. guttata 99.8 1300
XP_003207495.1 PREDICTED: splicing factor 3B subunit 1-like M. gallopavo 99.6 1304
XP_003227044.1 PREDICTED: splicing factor 3B subunit 1-like A. carolinensis 99.5 1301
NP_001084150.1 splicing factor 3B subunit 1 X. laevis 98.9 1306
XP_684311.1 PREDICTED: splicing factor 3B subunit 1 isoform 1 D. rerio 97.6 1314
NP_608534.2 CG2807, isoform A D. melanogaster 88.5 1339
NP_201232.1 putative splicing factor A. thaliana 82.8 1266
NP_497853.1 Protein T08A11.2 C. elegans 80.6 1316
XP_964047.1 U2 snRNP component prp10 N. crassa 78.8 1079
XP_001700562.1 nuclear pre-mRNA splicing factor, component of splicing factor 3b C. reinhardtii 78.2 605
NP_014015.1 Hsh155p S. cerevisiae 61.6 899
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_002931569.1 PREDICTED: splicing factor 3B subunit 1 X. tropicalis 98.8 1301
XP_004085416.1 PREDICTED: splicing factor 3B subunit 1-like O. latipes 97.5 1313

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; mixed; mouth; lung; skin; liver; thyroid; uncharacterized tissue; kidney; placenta; embryonic tissue; mammary gland; uterus; stomach; connective tissue; heart; eye; lymph node; cervix; vascular; adrenal gland; testis; pancreas; ascites; lymph; spleen; bone; ear; blood; bone marrow; prostate; muscle; ovary; thymus; esophagus; larynx; pharynx; salivary gland; pineal gland; trachea; bladder; adipose tissue; spinal cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q33.1
UniSTS entry: Chr 2 EST23H7
UniSTS entry: Chr 2 RH66152
UniSTS entry: Chr 2 MARC_15343-15344:1013437555:1
UniSTS entry: Chr 2 G54156
UniSTS entry: A006O45
UniSTS entry: Chr 2 SF3B1-1
UniSTS entry: Chr 2 MARC_11487-11488:1000830916:1
UniSTS entry: Chr 2 RH118649
UniSTS entry: Chr 17 STS-X53683 [Map Viewer]
UniSTS entry: Chr 17 STS-M69203 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AF070540.1 Homo sapiens clone 24647 putative nuclear protein mRNA, partial cds PA
AF054284.1 Homo sapiens spliceosomal protein SAP 155 mRNA, complete cds PA
BC046140.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:5755022) PA
BC056155.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:3908845), partial cds PA
BC064335.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:3870300) PA
AL137410.1 Homo sapiens mRNA; cDNA DKFZp434M052 (from clone DKFZp434M052); partial cds PA
NM_012433.2 Homo sapiens splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 1, mRNA PA
NM_001005526.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2, mRNA PA
BC107883.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:6673680), partial cds PA
AK057684.1 Homo sapiens cDNA FLJ33122 fis, clone TRACH2001428, highly similar to Rattus norvegicus strain Sprague-Dawley spliceosomal protein SAP155 mRNA P
AK290470.1 Homo sapiens cDNA FLJ76385 complete cds, highly similar to Homo sapiens splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2, mRNA P
AK308122.1 Homo sapiens cDNA, FLJ98070 P
AK294851.1 Homo sapiens cDNA FLJ57368 complete cds, highly similar to Splicing factor 3B subunit 1 P
BC029418.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:4250539), partial cds PA
BC015530.1 Homo sapiens splicing factor 3b, subunit 1, 155kDa, mRNA (cDNA clone IMAGE:3913474), partial cds PA
AF086296.1 Homo sapiens full length insert cDNA clone ZD50B08 PA
BC039020.1 Homo sapiens, Similar to splicing factor 3b, subunit 1, 155 kDa, clone IMAGE:6043857, mRNA PA

EST sequences (10 of 865) [Show all sequences]

AA947549.1 Clone IMAGE:1374916 ovary A
AA968641.1 Clone IMAGE:1592240 kidney 3' read
AA910962.1 Clone IMAGE:1518996 uncharacterized tissue 3' read PA
AA923500.1 Clone IMAGE:1534571 kidney 3' read A
AI004713.1 Clone IMAGE:1624572 embryonic tissue 3' read A
AI018712.1 Clone IMAGE:1642033 testis 3' read P
AI025114.1 Clone IMAGE:1631752 mammary gland 3' read A
AI038034.1 Clone IMAGE:1657788 embryonic tissue 3' read A
AA947329.1 Clone IMAGE:1589714 kidney 3' read A
AI074527.1 Clone IMAGE:1672032 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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