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UGID:2139073     UniGene Hs.632179     Homo sapiens (human)   LAT
Linker for activation of T cells (LAT)

Human protein-coding gene LAT. Represented by 154 ESTs from 71 cDNA libraries. EST representation biased toward juvenile. Corresponds to 4 reference sequences (different isoforms). [UniGene 2139073 - Hs.632179]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001014989.2 LAT gene product H. sapiens 100.0 268
NP_034819.1 Lat gene product M. musculus 69.8 241
Other hits (2 of 9) [Show all]SpeciesId(%)Len(aa)
XP_001147360.2 PREDICTED: linker for activation of T-cells family member 1 P. troglodytes 99.2 267
XP_001102058.2 PREDICTED: linker for activation of T-cells family member 1 M. mulatta 96.6 233

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; thymus; uncharacterized tissue; mixed; intestine; thyroid; lung; uterus; mouth; mammary gland; spleen; ovary; tonsil; eye; heart; liver; kidney; pancreas; skin; larynx; nerve; testis; brain; muscle; bone; prostate
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 1 L17705
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_014387.3 Homo sapiens linker for activation of T cells (LAT), transcript variant 1, mRNA PA
NM_001014989.1 Homo sapiens linker for activation of T cells (LAT), transcript variant 4, mRNA PA
NM_001014988.1 Homo sapiens linker for activation of T cells (LAT), transcript variant 3, mRNA PA
NM_001014987.1 Homo sapiens linker for activation of T cells (LAT), transcript variant 2, mRNA PA
BC011563.1 Homo sapiens linker for activation of T cells, mRNA (cDNA clone MGC:20145 IMAGE:4644259), complete cds PA
AK307342.1 Homo sapiens cDNA, FLJ97290
AK093815.1 Homo sapiens cDNA FLJ36496 fis, clone THYMU2018819
FN432834.1 Homo sapiens mRNA for linker for activation of T-cells family member 1 (LAT gene), transcript variant Del116 P
FN432833.1 Homo sapiens mRNA for linker for activation of T-cells family member 1 (LAT gene), transcript variant Del30 P
FN432832.1 Homo sapiens mRNA for linker for activation of T-cells family member 1 (LAT gene), transcript variant Del3 P
FN432831.1 Homo sapiens mRNA for linker for activation of T-cells family member 1 (LAT gene), transcript variant Ins27 P
AJ223280.1 Homo sapiens mRNA for tyrosine-phosphorylated protein of 36 kD (pp36) (LAT gene) P
AF036905.1 Homo sapiens linker for activation of T cells (LAT) mRNA, complete cds PA
AF036906.1 Homo sapiens linker for activation of T cells (LAT) mRNA, alternatively spliced form, complete cds P

EST sequences (10 of 154) [Show all sequences]

AA987807.1 Clone IMAGE:1588864 kidney 3' read A
AI093373.1 Clone IMAGE:1695127 uterus 3' read
BX107839.1 Clone IMAGp998O16790_;_IMAGE:345831 heart A
CB160324.1 Clone L18POOL1n1-15-D09 liver 5' read
AI224538.1 Clone IMAGE:1858349 mixed 3' read A
AI288988.1 Clone IMAGE:1879237 mixed 3' read A
AI660754.1 Clone IMAGE:2346115 thymus 3' read A
AI765093.1 Clone IMAGE:2393455 intestine 3' read A
AI769822.1 Clone IMAGE:2403356 kidney 3' read
AI922013.1 Clone IMAGE:2452828 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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