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UGID:2138983     UniGene Hs.632089     Homo sapiens (human)   EXOSC1
Exosome component 1 (EXOSC1)

Human protein-coding gene EXOSC1. Represented by 255 ESTs from 135 cDNA libraries. Corresponds to reference sequence NM_016046.3. [UniGene 2138983 - Hs.632089]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001103710.1 PREDICTED: 3'-5' exoribonuclease CSL4 homolog M. mulatta 100.0 194
XP_003904125.1 PREDICTED: exosome complex component CSL4 P. anubis 100.0 194
XP_507960.2 PREDICTED: exosome complex component CSL4 P. troglodytes 100.0 194
NP_057130.1 EXOSC1 gene product H. sapiens 100.0 194
NP_079920.1 Exosc1 gene product M. musculus 97.4 194
NP_001139039.1 exosc1 gene product D. rerio 88.6 193
NP_001086901.1 exosome component 1 X. laevis 86.1 193
NP_609492.1 Csl4 D. melanogaster 48.1 187
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001501548.1 PREDICTED: exosome complex component CSL4-like E. caballus 98.5 194
NP_001015529.1 EXOSC1 gene product B. taurus 98.5 194

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; mixed; lung; embryonic tissue; placenta; testis; bone marrow; thyroid; spleen; prostate; kidney; pancreas; pharynx; mouth; skin; uterus; heart; ovary; uncharacterized tissue; esophagus; blood; parathyroid; connective tissue; liver; eye; thymus; lymph node; trachea; ascites; bone; pineal gland; mammary gland; stomach; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24
UniSTS entry: Chr 10 SHGC-132201
UniSTS entry: Chr 10 D10S2396 [Map Viewer]
UniSTS entry: Chr 10 WI-11032
UniSTS entry: Chr 10 EXOSC1
UniSTS entry: Chr 4 D1S3697
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_016046.3 Homo sapiens exosome component 1 (EXOSC1), mRNA P
BC022067.2 Homo sapiens exosome component 1, mRNA (cDNA clone MGC:33030 IMAGE:4817073), complete cds PA
AK313717.1 Homo sapiens cDNA, FLJ94310, Homo sapiens exosomal core protein CSL4 (CSL4), mRNA P
AK307229.1 Homo sapiens cDNA, FLJ97177 P

EST sequences (10 of 255) [Show all sequences]

AA983327.1 Clone IMAGE:1590405 kidney 3' read A
AA983509.1 Clone IMAGE:1598373 uncharacterized tissue 3' read
AA985684.1 Clone IMAGE:1601323 lung 3' read
AI031809.1 Clone IMAGE:1645966 parathyroid 3' read PA
AI039025.1 Clone IMAGE:1657810 embryonic tissue 3' read A
AI073584.1 Clone IMAGE:1665102 skin 3' read A
AI097008.1 Clone IMAGE:1707040 heart 3' read PA
AI129539.1 Clone IMAGE:1711539 uterus 3' read A
AI085120.1 Clone IMAGE:1665946 skin 3' read A
BX108906.1 Clone IMAGp998J04219_;_IMAGE:145635 placenta P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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